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Chapter and Conference Paper
A Mathematical Model of Cell Clustering
This paper presents a numerical method for modelling cell migration. The aim of this research is to generate a model that accurately simulates to what can be observed in a experimental work. In the model prese...
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Article
Open AccessCorrection to: Digital messaging to support control for type 2 diabetes (StAR2D): a multicentre randomised controlled trial
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Article
Open AccessDigital messaging to support control for type 2 diabetes (StAR2D): a multicentre randomised controlled trial
Failure to take medicines for diabetes as prescribed contributes to poor outcomes from the condition. Mobile phones are ubiquitous and short message service (SMS) texts have shown promise as a low-cost interve...
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Article
Open AccessProcess evaluation of a brief messaging intervention to improve diabetes treatment adherence in sub-Saharan Africa
The SMS text Adherence suppoRt for people with type 2 diabetes (StAR2D) intervention is a pragmatic randomised controlled trial, testing the effectiveness of brief text messaging for improving clinical outcome...
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Article
Open AccessFeasibility, user experiences, and preliminary effect of Conversation Cards for Adolescents© on collaborative goal-setting and behavior change: protocol for a pilot randomized controlled trial
Adolescents and providers can benefit from practical tools targeting lifestyle modification for obesity prevention and management. We created Conversation Cards for Adolescents© (CCAs), a patient-centered communi...
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Article
New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation
Genome-wide association studies have generally failed to identify polymorphisms associated with antidepressant response. Possible reasons include limited coverage of genetic variants that this study tried to a...
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Article
Open AccessSecondary prevention of fractures after hip fracture: a qualitative study of effective service delivery
There is variation in how services to prevent secondary fractures after hip fracture are delivered and no consensus on best models of care. This study identifies healthcare professionals’ views on effective ca...
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Article
Open AccessInvestigation of blood mRNA biomarkers for suicidality in an independent sample
Changes in the blood expression levels of SAT1, PTEN, MAP3K3 and MARCKS genes have been reported as biomarkers of high versus low suicidality state (Le-Niculescu et al.). Here, we investigate these expression bio...
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Article
A genome-wide association study of anorexia nervosa
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome-wide association study (GWAS) have yielded si...
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Article
Copy number variants and therapeutic response to antidepressant medication in major depressive disorder
It would be beneficial to find genetic predictors of antidepressant response to help personalise treatment of major depressive disorder (MDD). Rare copy number variants (CNVs) have been implicated in several p...
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Article
Common variant at 16p11.2 conferring risk of psychosis
Epidemiological and genetic data support the notion that schizophrenia and bipolar disorder share genetic risk factors. In our previous genome-wide association study, meta-analysis and follow-up (totaling as m...
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Article
Association at SYNE1 in both bipolar disorder and recurrent major depression
Genome-wide association studies (GWAS) have identified a number of loci that have strong support for their association with bipolar disorder (BD). The Psychiatric Genome-Wide Association Study (GWAS) Consortiu...
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Article
Open AccessAntileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells
Drugs that target the chief mediator of nuclear export, chromosome region maintenance 1 protein (CRM1) have potential as therapeutics for leukemia, but existing CRM1 inhibitors show variable potencies and a br...
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Article
Open Accesshttp://www.euro-wabb.org: an EU Register for Alstrom, Bardet Biedl andother rare syndromes
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Article
Open AccessNeurotrophic gene polymorphisms and response to psychological therapy
Therapygenetics, the study of genetic determinants of response to psychological therapies, is in its infancy. Here, we investigate whether single-nucleotide polymorphisms in nerve growth factor (NGF) (rs6330) and...
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Article
Therapygenetics: the 5HTTLPR and response to psychological therapy
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Article
Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project
Suicidal thoughts during antidepressant treatment have been the focus of several candidate gene association studies. The aim of the present genome-wide association study was to identify additional genetic vari...
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Article
Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder
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Article
Erratum: Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype
Correction to: Molecular Psychiatry (2010) 15, 146–153; published online 1 July 2008; doi:10.1038/mp.2008.66 In the abstract of the published version of this article it was stated that association signals were...
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Article
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha
We earlier reported a genome-wide significant linkage to schizophrenia at chromosome 17 that was identified in a single pedigree (C702) consisting of six affected, male siblings with DSM-IV schizophrenia and p...
