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Article
The growth hormone response to hexarelin in patients with Prader-Willi syndrome
Hexarelin (Hex) is a synthetic hexapeptide with potent GH-releasing activity in both animals and men. Aim of this study was to evaluate the GH response to a maximal dose of Hex and GH-releasing hormone (GHRH) ...
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Article
Growth hormone binding protein activity in obese children
We evaluated growth hormone binding protein (GHBP) activity in a group of obese children (12 boys and 12 girls, age 3.1–14.7 years, BMI 21.1–33.3, 11 prepubertal and 13 early pubertal) and in 26 age-matched no...
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Article
Growth hormone (GH) response to GH-releasing hormone in short children: Lack of correlation with endogenous nocturnal GH secretion
The growth hormone (GH) response to iv administration of GH-releasing hormone (GHRH, 0.3 µg/Kg) was evaluated in 21 short children (13 boys and 8 girls, age 6.7–13.8 yr). Fourteen had familial short stature an...
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Article
Growth hormone response to oral clonidine test in normal and short children
We evaluated the growth hormone (GH) response to an acute Clonidine test (0.15 mg/m2 po) in 30 normal prepubertal children (stature between the 3rd and 97th centile), in 29 short children (stature <3rd centile fo...
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Article
Secretion of growth hormone releasing hormone in obese children
We have evaluated baseline and I-dopa-stimulated peripheral growth hormone releasing hormone (pGHRH) secretion in 6 obese prepubertal children and in 7 age-matched controls. Baseline pGHRH levels were no diffe...
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Article
The growth hormone response to pyridostigmine plus growth hormone releasing hormone is not influenced by pubertal maturation
We have evaluated the effect of pubertal maturation on the GH response to growth hormone releasing hormone (GHRH), pyridostigmine (PD), and the combined administration of PD + GHRH in a group of short normal c...
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Article
Sexual maturation and adrenal function in girls with thalassemia
Adrenal steroid production was evaluated in 12 thalassemic girls aged between 18 and 22 years and at stage P1 of sexual maturation according to Tanner. The values found in these patients were compared with tho...
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Article
Adrenal and testicular function in boys affected by thalassemia
The adrenal androgen secretion and testicular function were studied in 6 thalassemic boys aged between 16 and 20 years. Six normal boys of the same age and 6 at the same pubertal stage (P1 according to Tanner)...
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Article
Effect of short dexamethasone suppression on plasma steroids in prepubertal and pubertal girls
In 40 girls aged from 2 to 14 years, subdivided into groups according to age and pubertal development, and in 6 adult female volunteers, plasma Cortisol (F), pregnenolone (δ5), de-hydroepiandrosterone (DHA), prog...
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Article
Adrenal and gonadal steroids and pituitary response to LHRH in girls. I. Delayed puberty
Plasma levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), dehydroepiandrosterone (DHA), dehydroepiandrosterone-sulphate (DHA-S), 17-hydroxyprogesterone (17P), androstenedione (A), testoste...
