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Article
Open AccessEbola virus infection induces autoimmunity against dsDNA and HSP60
Ebola virus (EBOV) survivors are affected by a variety of serious illnesses of unknown origin for years after viral clearance from the circulation. Identifying the causes of these persistent illnesses is param...
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Article
Survey of laboratory-acquired infections around the world in biosafety level 3 and 4 laboratories
Laboratory-acquired infections due to a variety of bacteria, viruses, parasites, and fungi have been described over the last century, and laboratory workers are at risk of exposure to these infectious agents. ...
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Article
Open AccessLongitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection
Data on immune responses during human Ebola virus disease (EVD) are scanty, due to limitations imposed by biosafety requirements and logistics. A sustained activation of T-cells was recently described but func...
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Article
Open AccessMolecular mechanisms of Ebola virus pathogenesis: focus on cell death
Ebola virus (EBOV) belongs to the Filoviridae family and is responsible for a severe disease characterized by the sudden onset of fever and malaise accompanied by other non-specific signs and symptoms; in 30–50% ...
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Article
Bcl-2 inhibits the caspase-dependent apoptosis induced by SARS-CoV without affecting virus replication kinetics
Vero cells transfected with either neo- or bcl-2-plasmid were infected with SARS-CoV at a high multiplicity of infection. Apoptosis appeared after the onset of CPE and completion of virus replication, and could b...
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Chapter and Conference Paper
Influence of Waste Water Disinfection Treatments on Some Genotoxic Chemical Micropollutants
This study compares the effects of different waste water treatments using sodium hypochlorite, chlorine dioxide and ozone on some chemical and biological parameters. The samples studied were obtained from an a...