33 Result(s)

Article

Phenoty** normal kidney function in elderly patients with type 2 diabetes: a cross-sectional multicentre study

Type 2 diabetes (T2D) accelerates the decline in glomerular function; however, some individuals do not develop chronic kidney disease despite advanced age and long-lasting T2D. We aimed to phenotype patients w...

G P Fadini, A Solini, M L Manca, G Zatti, I Karamouzis… in Acta Diabetologica (2018)

Article

hMENA^11a contributes to HER3-mediated resistance to PI3K inhibitors in HER2-overexpressing breast cancer cells

Human Mena (hMENA), an actin regulatory protein of the ENA/VASP family, cooperates with ErbB receptor family signaling in breast cancer. It is overexpressed in high-risk preneoplastic lesions and in primary br...

P Trono, F Di Modugno, R Circo, S Spada, A Di Benedetto, R Melchionna… in Oncogene (2016)

Article

TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells

Metastatic growth in breast cancer (BC) has been proposed as an exclusive property of cancer stem cells (CSCs). However, formal proof of their identity as cells of origin of recurrences at distant sites and th...

M Bartucci, R Dattilo, C Moriconi, A Pagliuca, M Mottolese, G Federici… in Oncogene (2015)

Article

Management of mineral metabolism in haemodialysis patients: need for new strategies

P Esposito, A Di Benedetto, T Rampino, S Stuard… in European Journal of Clinical Nutrition (2014)

Article

ATM kinase activity modulates ITCH E3-ubiquitin ligase activity

Ataxia Telangiectasia Mutated (ATM) kinase, a central regulator of the DNA damage response, regulates the activity of several E3-ubiquitin ligases, and the ubiquitination-proteasome system is a consistent targ...

S Santini, V Stagni, R Giambruno, G Fianco, A Di Benedetto, M Mottolese… in Oncogene (2014)

Article

Phalangeal quantitative ultrasound and metabolic control in pre-menopausal women with Type 1 diabetes mellitus

Background: Several studies have reported increased fracture risk in Type 1 diabetes mellitus (T1 DM). Quantitative Ultrasound (QUS) provides information on the structure and elastic properties o...

A. Catalano MD, N. Morabito, G. Di Vieste… in Journal of Endocrinological Investigation (2013)

Chapter and Conference Paper

Software para Controle do Desempenho Escolar

Given the teachers’ needs to explore and monitor the students’ responses to a given teaching-learning methodology, computational tools may be used to compare the assessment scores in order to identify learning...

V. S. Sato, A. Di Benedetto, J. J. Bonvent… in V Latin American Congress on Biomedical En… (2013)

Article

Direct regulation of microRNA biogenesis and expression by estrogen receptor beta in hormone-responsive breast cancer

Estrogen effects on mammary epithelial and breast cancer (BC) cells are mediated by the nuclear receptors ERα and ERβ, transcription factors that display functional antagonism with each other, with ERβ acting ...

O Paris, L Ferraro, O M V Grober, M Ravo, M R De Filippo, G Giurato, G Nassa… in Oncogene (2012)

Article

Mass Transfer Velocity and Momentum Vertical Exchange in Simulated Deep Street Canyons

A box model to simulate mass transfer inside deep street canyons and with atmospheric flow above is introduced and discussed. Two ideal deep street canyons with aspect ratios of 3 and 5 (the aspect ratio being...

F. Murena, A. Di Benedetto, M. D’Onofrio, G. Vitiello in Boundary-Layer Meteorology (2011)

Chapter and Conference Paper

LES and Laser Measurements of Dynamic Flame/Vortex Interactions

The dynamic interaction that occurs between a propagating flame front and a rotating vortex structure is one of the key mechanisms within turbulent combustion [1]. As such, it is found within many applications...

V. Di Sarli, A. Di Benedetto, G. Russo, E. J. Long… in Direct and Large-Eddy Simulation VII (2010)

Article

Large Eddy Simulation and PIV Measurements of Unsteady Premixed Flames Accelerated by Obstacles

In gas explosions, the unsteady coupling of the propagating flame and the flow field induced by the presence of blockages along the flame path produces vortices of different scales ahead of the flame front. Th...

V. Di Sarli, A. Di Benedetto, G. Russo, S. Jarvis… in Flow, Turbulence and Combustion (2009)

Article

Menopause modulates homocysteine levels in diabetic and non-diabetic women

High total homocysteine (tHcy) plasma levels may contribute to the increased cardiovascular risk of Type 2 diabetic women. However, to date, data on factors modulating tHcy concentration in this population are...

G. T. Russo MD, A. Di Benedetto, E. Alessi… in Journal of Endocrinological Investigation (2008)

Article

Functional study of the transplanted kidney with power Doppler US and time/intensity curves

Power Doppler ultrasound (US) with time-intensity curves was used to study renal graft function both in the absence of disease and with complications (acute tubular necrosis and chronic rejection) in an attemp...

R. Farina, F. Pennisi, M. La Rosa, C. Puglisi, A. Di Benedetto… in La radiologia medica (2007)

Article

Mild hyperhomocysteinemia and the common C677T polymorphism of methylene tetrahydrofolate reductase gene are not associated with the metabolic syndrome in Type 2 diabetes

A moderate increase of total homocysteine (tHcy) plasma levels seems to increase cardiovascular disease (CVD) risk in Type 2 diabetic subjects, but its relationship with diabetes and insulin-resistance is stil...

G. T. Russo MD, A. Di Benedetto, E. Alessi… in Journal of Endocrinological Investigation (2006)