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Article

Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor

Pain places a devastating burden on patients and society and current pain therapeutics exhibit limitations in efficacy, unwanted side effects and the potential for drug abuse and diversion. Although genetic ev...

M. Flinspach, Q. Xu, A. D. Piekarz, R. Fellows, R. Hagan, A. Gibbs… in Scientific Reports (2017)