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Article
Venous thromboembolism in patients with Cushing’s syndrome: need of a careful investigation of the prothrombotic risk profile
A high incidence of venous thromboembolic (VTE) complications has been reported in Cushing’s syndrome (CS), mostly post-operatively and attributable to hypercoagulability. The prevalence of symptomatic VTE was...
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Article
Arterial and venous thrombosis in patients with von Willebrand’s disease: A critical review of the literature
All patients with von Willebrand’s disease (vWD) who showed an arterial or venous thrombosis and were reported in the literature have been evaluated. 11 patients had arterial thrombosis while 19 had venous thr...
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Article
Different organization of von Willebrand factor oligomers in type-2A and -2B von Willebrand disease variants: effects of DDAVP infusion and protease inhibitors
Plasma von Willebrand factor (vWf) displays a complex pattern of repeating multimers, whose heterogeneous size distribution seems to depend on the proteolytic cleavage of the constituent vWf subunit. Smaller v...
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Article
Detection of two missense mutations and characterization of a repeat polymorphism in the factor VII gene (F7)
The 3′ portion of the coagulation factor VII gene, containing the activation and serine protease domains, was investigated in four subjects with factor VII deficiency by temperature gradient gel electrophoresi...
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Article
A frequent factor XII gene mutation in Hageman trait
An additionalTaqI restriction site was mapped in intron 2 of the factor XII gene. The site was found only in subjects with total or partial factor XII deficiency and thus represents the true gene lesion or a very...
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Article
Discrepancies between von willebrand factor multimeric composition and other tests in some von willebrand's disease variants
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Article
Increased factor VIII/vWf levels in patients with reduced platelet number
Factor VIII/von Willebrand factor (VIII/vWf) related properties were studied in twenty six patients with thrombocytopenia. Fifteen patients were affected by idiophatic thrombocytopenic purpura (ITP) and 11 pat...
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Chapter
Abnormal Platelet Aggregation in Patients with Bartter’s Syndrome
Bartter’s syndrome is characterized by hypokalemia, hyperreninemia, hyperaldosteronism without hypertension, and juxtaglomerular cell hyperplasia.1 Recent studies have demonstrated an increase of the urinary excr...
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Article
The possible value of platelet aggregation studies in patients with increased platelet number
ADP, adrenalin and collagen platelet aggregation studies were performed in 54 patients with elevated platelet counts: 38 patients showed primary thrombocythemia and 16 secondary thrombocytosis. Patients with p...