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Open AccessComparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study)
The effectiveness of ranibizumab in the treatment of diabetic macular edema has been proven with large clinical trials. For bevacizumab only two clinical trials have been published and a head-to-head compariso...
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Article
Fasting proinsulin levels are significantly associated with 20 year cancer mortality rates. The Hoorn Study
Proinsulin is possibly associated with cancer through activation of insulin receptor isoform A. We sought to investigate the associations between proinsulin and 20 year cancer mortality rates.
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Article
Open AccessDiffusion tensor imaging in type 1 diabetes: decreased white matter integrity relates to cognitive functions
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16 Tumoren van het oog
De uvea van het oog bestaat uit drie delen: choroidea, corpus ciliare en iris. In de gepigmenteerde cellen van de uvea (melanocyten) kan een kwaadaardige tumor ontstaan: het uveamelanoom.
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Article
Diabetische retinopathie
Diabetische retinopathie is een ziekte van de kleine bloedvaten in het netvlies van patiënten met diabetes mellitus waarbij vaatwandlekkage en nieuwvorming van vaten de functie van het oog en daarmee het gezic...
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Article
Evaluation of Cross-sectional and Longitudinal Construct Validity of Two Vision-related Quality of Life Questionnaires: The LVQOL and VCM1
The Low Vision Quality of Life (LVQOL) questionnaire and the Vision-related Quality of Life Core Measure (VCM1) are two of the many vision-related quality of life (QOL) questionnaires that have been developed ...
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Article
Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study
The exact pathogenesis of retinopathy in diabetic and non-diabetic individuals is incompletely understood, but may involve chronic low-grade inflammation and dysfunction of the vascular endothelium. The aim of...
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35th Annual Meeting of the European Association for the Study of Diabetes
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Article
Second primary tumours in hereditary- and nonhereditary retinoblastoma patients treated with megavoltage external beam irradiation
The purpose of this retrospective study is to investigate the influence of 45 Gy megavoltage external beam radiotherapy on the occurrence of second primary tumours in hereditary- and non-hereditary retinoblast...
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Article
High parental age is associated with sporadic hereditary retinoblastoma: the Dutch retinoblastoma register 1862–1994
We wished to determine the influence of parental age at the birth of a retinoblastoma patient on the risk of sporadic hereditary retinoblastoma. The parental age at birth of 941 patients of the Dutch retinobl...
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Article
Effect of donor cornea preservation in tissue culture and in McCarey-Kaufmann medium on corneal graft rejection and visual acuity
In a retrospective study the rate of rejection and clouding of the donor cornea for other reasons was investigated in 230 penetrating keratoplasties performed between 1984–1986. Donor corneas were stored in Mc...
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Article
Anticoagulant therapy and cataract surgery
A questionnaire was sent round to the 200 members of the Netherlands Intraocular Implant Club (NIOIC), in which they were asked about the policy followed in 1988 with regard to anticoagulant therapy (ACT) and ...