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Article
Mars Oxygen ISRU Experiment (MOXIE)
MOXIE is a technology demonstration that addresses the Mars 2020 (Perseverance) objective of preparing for future human exploration by demonstrating In Situ Resource Utilization (ISRU) in the form of dissociating...
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Reference Work Entry In depth
International Federation on Ageing
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Chapter and Conference Paper
Thinking Bias: The Hidden Talent Excluder
Large numbers of organisations use interviews and psychometric tests as methods of recruiting new employees. The inherent biases of these approaches are examined here for a number of common scenarios and the i...
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Article
Open AccessCorrection: Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Living Reference Work Entry In depth
International Federation on Ageing
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Article
Open AccessErratum: Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups
Correction to: Leukemia (2018) 32, 332–342; doi: 10.1038/leu.2017.177; published online 27 June 2017 Since the publication of this article, the authors have identified an omission in their paper, namely that t...
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Article
Open AccessWhole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups
Chronic lymphocytic leukaemia (CLL) consists of two biologically and clinically distinct subtypes defined by the abundance of somatic hypermutation (SHM) affecting the Ig variable heavy-chain locus (IgHV). The...
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Article
Targeted deep sequencing reveals clinically relevant subclonal IgHV rearrangements in chronic lymphocytic leukemia
The immunoglobulin heavy-chain variable region gene (IgHV) mutational status is considered the gold standard of prognostication in chronic lymphocytic leukemia (CLL) and is currently determined by Sanger seque...
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Article
Open AccessTargeted resequencing analysis of 31 genes commonly mutated in myeloid disorders in serial samples from myelodysplastic syndrome patients showing disease progression
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Article
Whole-exome sequencing in del(5q) myelodysplastic syndromes in transformation to acute myeloid leukemia
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Article
Open AccessQuantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia
Genome-wide array approaches and sequencing analyses are powerful tools for identifying genetic aberrations in cancers, including leukemias and lymphomas. However, the clinical and biological significance of s...
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Article
Partitioned EDF scheduling for multiprocessors using a C=D task splitting scheme
An EDF-based task-splitting scheme for scheduling multiprocessor systems is presented in this paper. For m processors at most m−1 tasks are split. The first part of a split task is constrained to have a deadline ...
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Article
Follow-up for Alzheimer patients: European Alzheimer disease consortium position paper
Alzheimer disease (AD) is one of the leading causes of dependence in the elderly. Providing care for patients with AD is complex and the type of care required depends on the stage of the disease and varies ove...
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Article
Exact scheduling analysis of non-accumulatively monotonic multiframe tasks
In this paper, we present exact analysis for the worst case response time of the general multiframe (MF) task model executing on a uniprocessor according to the fixed priority scheduling scheme. The analysis i...
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Article
An engineering process for the verification of real-time systems
The complete verification of the timing properties of a large critical system cannot be undertaken in a single step or with a single method. In this paper we present a process that links together a number of t...
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Article
Timing Analysis of Real-Time Communication Under Electromagnetic Interference
This paper discusses aspects of dependability of real-time communication. In particular, we consider timing behaviour under fault conditions for Controller Area Network (CAN) and the extension Time-triggered C...
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Article
Right-hemisphere encephalopathy in elderly subjects with schizophrenia: evidence from neuropsychological and brain imaging studies
Cognitive impairment is a recognised feature of schizophrenia. Elderly patients with early-acquired schizophrenia are seriously affected, with a proportion of them showing clinically significant dementia, not ...
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Article
The Valid Use of Utility in Adaptive Real-Time Systems
Real-time systems that must adapt their behavior to changes in internal and external circumstances require flexibility in their scheduling. One approach that has been advocated for achieving this flexibility i...
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Article
An Integrated Approach to Scheduling in Safety-Critical Embedded Control Systems
This paper describes an approach that has been developed over a number of years for the job of scheduling systems and providing evidence that timing requirements are met. The approach has been targeted at the ...
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Article
How to Verify a Safe Real-Time System: The Application of Model Checking and Timed Automata to the Production Cell Case Study*
The formal verification of a real-time system requires either a proof theoretic or model theoretic approach. Both being applicable to a model of the proposed behavior of the concurrent real-time system. This p...
