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  1. Article

    Open Access

    Author Correction: Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott–Aldrich syndrome

    A. Magnani, M. Semeraro, F. Adam, C. Booth, L. Dupré, E. C. Morris… in Nature Medicine (2022)

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  2. Article

    Open Access

    Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott–Aldrich syndrome

    Patients with Wiskott–Aldrich syndrome (WAS) lacking a human leukocyte antigen-matched donor may benefit from gene therapy through the provision of gene-corrected, autologous hematopoietic stem/progenitor cell...

    A. Magnani, M. Semeraro, F. Adam, C. Booth, L. Dupré, E. C. Morris… in Nature Medicine (2022)

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  3. Article

    Open Access

    Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia

    Precise classification of acute leukemia (AL) is crucial for adequate treatment. EuroFlow has previously designed an AL orientation tube (ALOT) to guide towards the relevant classification panel (T-cell acute ...

    L Lhermitte, E Mejstrikova, A J van der Sluijs-Gelling, G E Grigore, L Sedek… in Leukemia (2018)

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  4. No Access

    Article

    TCRα rearrangements identify a subgroup of NKL-deregulated adult T-ALLs associated with favorable outcome

    T-cell acute lymphoblastic leukemia (T-ALL) results from leukemic transformation of T-cell precursors arrested at specific differentiation stages, including an ‘early-cortical’ thymic maturation arrest charact...

    P Villarese, C Lours, A Trinquand, S Le Noir, M Belhocine, L Lhermitte… in Leukemia (2018)

  5. No Access

    Article

    Age-related clinical and biological features of PTEN abnormalities in T-cell acute lymphoblastic leukaemia

    The tumour suppressor gene PTEN is commonly altered in T-cell acute lymphoblastic leukaemia but its prognostic impact is still debated. We screened a cohort of 573 fully characterised adult and paediatric T-cell ...

    M Tesio, A Trinquand, P Ballerini, G Hypolite, L Lhermitte, A Petit, N Ifrah… in Leukemia (2017)

  6. Article

    Open Access

    Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality

    M Artesi, A Marçais, K Durkin, N Rosewick, V Hahaut, F Suarez, A Trinquand… in Leukemia (2017)

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  7. No Access

    Article

    Oncogenic PTEN functions and models in T-cell malignancies

    PTEN is a protein phosphatase that is crucial to prevent the malignant transformation of T-cells. Although a numerous mechanisms regulate its expression and function, they are often altered in T-cell acute lym...

    M Tesio, A Trinquand, E Macintyre, V Asnafi in Oncogene (2016)

  8. No Access

    Article

    Receptor kinase profiles identify a rationale for multitarget kinase inhibition in immature T-ALL

    Constitutively activated FLT3 signaling is common in acute myeloid leukemia, and is currently under evaluation for targeted therapy, whereas little data is available in T-cell acute lymphoblastic leukemia (T-A...

    L Lhermitte, R Ben Abdelali, P Villarèse, N Bedjaoui, V Guillemot, A Trinquand… in Leukemia (2013)