27 Result(s)
within
A R Genazzani
Internal Medicine
-
Article
Polymorphisms of the FTO and MTHFR genes and vascular, inflammatory and metabolic marker levels in postmenopausal women
To determine the prevalence of three single nucleotide polymorphisms (SNPs) in postmenopausal women with and without the metabolic syndrome (METS) and to explore levels of circulating biomarkers of inflammatio...
-
Article
Pivagabine decreases stress-related hormone secretion in women with hypothalamic amenorrhea
Stress-induced neuroendocrine activities influence the regulation of endocrine glands and axes. Weight loss-related hypothalamic amenorrhea is a typical stress-induced physiopathological condition. It is chara...
-
Article
Activin A stimulates insulin secretion in cultured human pancreatic islets
Activin A is a dimeric glycoprotein showing a high sequence homology with transforming growth factor-ß (TGF-ß) and playing autocrine/ paracrine actions in reproductive tissues. However, since the synthesis of ...
-
Article
Hypothalamic amenorrhea and cardiovascular hormones: Changes of plasma calcitonin gene-related peptide and atrial natriuretic peptide levels
Typical modifications of cardiovascular activity and water and salt homeostasis throughout female reproductive life are well known. Differences in plasma levels of calcitonin gene-related peptide (CGRP) and at...
-
Article
Serum levels of dimeric activin A are not a marker of placental tumors in the course of chemotherapy
The aim of the present study was to evaluate whether serum activin A levels may represent, in addition to intact human chorionic gonadotrophin, a marker of placental tumors in the course of chemotherapy. Seria...
-
Article
Peritoneal fluid levels of immunoreactive corticotropin-releasing factor (CRF) and CRF-binding protein (CRF-BP) in healthy and endometriosic women
Corticotropin-releasing factor (CRF) is a 41-amino acid neurohormone involved in the neuroendocrine response to stress, also playing a role in cell-mediated immune functions and in inflammation. In the light o...
-
Article
Interrelationships between follicle stimulating hormone and the growth hormone - insulin-like growth factor - IGF-binding proteins axes in human granulosa cells in culture
As it has been hypothesized that IGF-binding proteins (IGFBPs) may have a role as autocrine/paracrine factors in regulating the local actions of the insulin-like growth factors (IGFs) in the ovary, we studied ...
-
Article
Involvement of μ-opioid receptors in the modulation of pituitary-adrenal axis in normal and stressed rats
The availability of the most selective, high-affinity, natural opioid agonists for μ-receptors (dermorphin-DM) and δ-receptors (deltorphin-DT) has provided the possibility for in vivo studying of the role of acut...
-
Article
A comparative, randomized study of three different progesterone support of the luteal phase following IVF/ET program
The use of luteal phase support has been demonstrated in patients undergoing IVF/ET in cycles stimulated after pituitary desensitization with gonadotrophin releasing hormone agonists. However, it is still not ...
-
Article
Ontogeny of the circadian rhythm in medial basal hypothalamic ß-endorphin content in female rat
The present study evaluated the possible role of estrogens in generating the circadian rhythm of medial basal hypothalamus content at the time of puberty in female rats. Accordingly, changes in medial basal hy...
-
Article
Maternal decidua and fetal membranes contain immunoreactive neuropeptide Y
The aim of the present study was to evaluate whether the various intrauterine tissues contain immunoreactive neuropeptide Y (NPY). Previous observations showed that human placenta produces NPY and that it may ...
-
Chapter
β-Endorphin in Human Reproduction
Of the endogenous opioid peptides, β-endorphin (β-EP) is the most deeply involved in endocrine function, as reflected by the neuroendocrine action of hypothalamic β-EP in the control of pituitary hormone relea...
-
Article
Effect of naltrexone treatment on the treadmill exercise-induced hormone release in amenorrheic women
The effect of an acute physical stress on hormone secretions before and after a 10-day naltrexone treatment in untrained healthy and amenorrheic women was investigated. Plasma levels of pituitary (LH, FSH, pro...
-
Article
Relationship between cerebrospinal fluid β-endorphin and plasma pituitary-gonadal hormone levels in women
Brain β-endorphin (β-EP) plays an important role in regulating the hypothalamus-pituitary-gonadal axis activity. Cerebrospinal fluid (CSF) β-EP levels seem to reflect the central rather than pituitary secretion. ...
-
Article
Plasma beta-endorphin and beta-lipotropin levels increase in well trained athletes after competition and non competitive exercise
Plasma ß-endorphin (ß-EP) and ß-lipotropin (ß-LPH) levels were measured in 15 healthy trained marathon runners. These hormones were evaluated in two different conditions: 1 — before (1 h) and after a marathon ...
-
Article
Oocyte fertilization in vitro is associated with high follicular immunoreactive ß-endorphin levels
Follicular fluid (FF) levels of immuno reactive ß-Endorphin (i.r. ß-EP), i.r. γ-Endorphin (i.r. γ-EP), i.r. α-melanocyte-stimulating hormone (i.r. α-MSH), androgens and estrogens were measured in 76 preovulato...
-
Article
Effects of bromocriptine on pituitary and adrenal cortex in pre-adrenarchal rabbits
The effect of bromocriptine on the morphological picture and steroid content of the adrenal gland, and on certain pro-opiomelanocortin (C) peptides in the pituitary gland was evaluated in preadrenarchal rabbit...
-
Article
Plasma B-endorphin resistance to dexamethasone suppression in obese patients
Patients with simple exogenous obesity are characterized by increased B-endorphin (B-EP) plasma levels, despite normal ACTH and B-Lipotropin (B-LPH). To evaluate the origin of such an hyperendorphinemia, 42 ob...
-
Article
Plasma β-endorphin, free fatty acids and blood lipid changes in type 2 (non-insulin dependent) diabetic patients
A lipolytic activity for β-endorphin (βEP) has been recently suggested both in vitro and in vivo. In our study we evaluated the relationship between βEP and blood lipid pattern in Type 2 (non-insulin dependent) d...
-
Article
Dissociation between CSF and plasma B-endorphin in major depressive disorders: evidence for a different regulation
Plasma and cerebrospinal fluid (CSF) levels of ACTH, B-lipotropin (B-LPH) and B-endorphin (B-EP) were simultaneously measured in 10 patients with major depression (35–57 yr) with a disease history of 10–34 yr,...
