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Article
Open AccessIs there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis?
We provide an evidence base and guidance for the use of menopausal hormone therapy (MHT) for the maintenance of skeletal health and prevention of future fractures in recently menopausal women. Despite controve...
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Article
Polymorphisms of the FTO and MTHFR genes and vascular, inflammatory and metabolic marker levels in postmenopausal women
To determine the prevalence of three single nucleotide polymorphisms (SNPs) in postmenopausal women with and without the metabolic syndrome (METS) and to explore levels of circulating biomarkers of inflammatio...
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Article
Sex hormonal regulation and hormesis in aging and longevity: role of vitagenes
Aging process is accompanied by hormonal changes characterized by an imbalance between catabolic hormones, such as cortisol and thyroid hormones which remain stable and hormones with anabolic effects (testoste...
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Article
Brain derived neurotrophic factor circulating levels in patients undergoing IVF
The aim of the study was to measure circulating BDNF levels, a neurotrophin recently identified in the ovary, in parallel with estradiol, to verify if assessing this factor could add any predictive value to th...
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Article
Pivagabine decreases stress-related hormone secretion in women with hypothalamic amenorrhea
Stress-induced neuroendocrine activities influence the regulation of endocrine glands and axes. Weight loss-related hypothalamic amenorrhea is a typical stress-induced physiopathological condition. It is chara...
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Article
Longitudinal Evaluation of Perimenopausal Femoral Bone Loss: Effects of a Low-Dose Oral Contraceptive Preparation on Bone Mineral Density and Metabolism
To characterize the pattern of biochemical markers of bone metabolism and femoral bone mineral density in eumenorrheic and oligomenorrheic perimenopausal women, and assess the effects of a low-dose oral contr...
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Article
Activin A stimulates insulin secretion in cultured human pancreatic islets
Activin A is a dimeric glycoprotein showing a high sequence homology with transforming growth factor-ß (TGF-ß) and playing autocrine/ paracrine actions in reproductive tissues. However, since the synthesis of ...
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Chapter
Central Nervous System
Gonadal hormones exert several effects on the central nervous system (CNS) throughout the lifespan and go beyond the traditional control of the reproductive function and the modulation of sexual behavior. The ...
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Article
Hypothalamic amenorrhea and cardiovascular hormones: Changes of plasma calcitonin gene-related peptide and atrial natriuretic peptide levels
Typical modifications of cardiovascular activity and water and salt homeostasis throughout female reproductive life are well known. Differences in plasma levels of calcitonin gene-related peptide (CGRP) and at...
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Article
Serum levels of dimeric activin A are not a marker of placental tumors in the course of chemotherapy
The aim of the present study was to evaluate whether serum activin A levels may represent, in addition to intact human chorionic gonadotrophin, a marker of placental tumors in the course of chemotherapy. Seria...
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Article
Peritoneal fluid levels of immunoreactive corticotropin-releasing factor (CRF) and CRF-binding protein (CRF-BP) in healthy and endometriosic women
Corticotropin-releasing factor (CRF) is a 41-amino acid neurohormone involved in the neuroendocrine response to stress, also playing a role in cell-mediated immune functions and in inflammation. In the light o...
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Article
Estrogens as neuromodulators
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Article
Clinical utility of adjuvant growth hormone in the treatment of patients with polycystic ovaries undergoing in vitro fertilization
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Article
Ipriflavone prevents the loss of bone mass in pharmacological menopause induced by GnRH-agonists
In a double-blind, placebo controlled study, ipriflavone (600 mg/day, T.D.D.) or identical placebo tablets were given with 500 mg/day of calcium to patients treated with the gonadotropin hormone-releasing horm...
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Article
Ipriflavone prevents the loss of bone mass in pharmacological menopause induced by GnRH-Agonist
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Article
Interrelationships between follicle stimulating hormone and the growth hormone - insulin-like growth factor - IGF-binding proteins axes in human granulosa cells in culture
As it has been hypothesized that IGF-binding proteins (IGFBPs) may have a role as autocrine/paracrine factors in regulating the local actions of the insulin-like growth factors (IGFs) in the ovary, we studied ...
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Article
Treatment of postmenopausal vertebral osteopenia with monofluorophospate: A long-term calcium-controlled study
The aim of the present study was to assess the effects of the new fluorine pro-drug monofluorophos-phate (MFP) in postmenopausal women with vertebral osteopenia and high bone turnover. We enrolled postmenopaus...
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Article
Involvement of μ-opioid receptors in the modulation of pituitary-adrenal axis in normal and stressed rats
The availability of the most selective, high-affinity, natural opioid agonists for μ-receptors (dermorphin-DM) and δ-receptors (deltorphin-DT) has provided the possibility for in vivo studying of the role of acut...
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Article
A comparative, randomized study of three different progesterone support of the luteal phase following IVF/ET program
The use of luteal phase support has been demonstrated in patients undergoing IVF/ET in cycles stimulated after pituitary desensitization with gonadotrophin releasing hormone agonists. However, it is still not ...
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Article
Ontogeny of the circadian rhythm in medial basal hypothalamic ß-endorphin content in female rat
The present study evaluated the possible role of estrogens in generating the circadian rhythm of medial basal hypothalamus content at the time of puberty in female rats. Accordingly, changes in medial basal hy...
