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Article
Open AccessConsideration of the Accuracy of Empirical and Indirect Laboratory Methods for the Characterisation of Tension Strength
This research explores the results of the most common laboratory based indirect tension strength methods over the range of UCS strengths 0.1 MPa (cemented paste backfill) to 100 MPa (concrete). The accuracy of...
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Article
Open AccessThe bifurcation and topography of the posterior tibial artery within the tarsal tunnel
The tarsal tunnel (TT) is a fibro-osseous anatomical space coursing from the medial ankle to the medial midfoot. This tunnel acts as a passage for both tendinous and neurovascular structures, including the neu...
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Article
Metallization of Porous Polyethylene Using a Wire-Arc Spray Process for Heat Transfer Applications
Metallization of polyethylene (PE) using thermal spray techniques has proved difficult due to its low melting point and softness. In this study, metallic coatings were applied on porous polyethylene substrates...
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Article
Open AccessAchieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: protocol for a randomised patient-focused pilot trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma
Melanoma is common; 15,906 people in the UK were diagnosed with melanoma in 2015 and incidence has increased fivefold in 30 years. Melanoma affects old and young people, with poor prognosis once metastatic. UK...
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Article
Open AccessProtocol for a Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose FLuoride toothpaste in preventing and treating dEntal Caries in high-risk older adulTs (reflect trial)
Dental caries in the expanding elderly, predominantly-dentate population is an emerging public health concern. Elderly individuals with heavily restored dentitions represent a clinical challenge and significan...
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Article
Open AccessBeyond Traditional Coatings: A Review on Thermal-Sprayed Functional and Smart Coatings
Thermal spraying has been present for over a century, being greatly refined and optimized during this time. It has become nowadays a reliable and cost-efficient method to deposit thick coatings with a wide var...
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Article
Open AccessElectroluminescence TPCs at the thermal diffusion limit
The NEXT experiment aims at searching for the hypothetical neutrinoless double-beta decay from the 136Xe isotope using a high-purity xenon TPC. Efficient discrimination of the events through pattern recognition o...
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Article
Open AccessMeasurement of radon-induced backgrounds in the NEXT double beta decay experiment
The measurement of the internal 222Rn activity in the NEXT-White detector during the so-called Run-II period with 136Xe-depleted xenon is discussed in detail, together with its implications for double beta decay ...
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Article
Open AccessLong-term results and recurrence patterns from SCALOP: a phase II randomised trial of gemcitabine- or capecitabine-based chemoradiation for locally advanced pancreatic cancer
SCALOP, a randomised, phase II trial, tested the activity and safety of gemcitabine (GEM)-based and capecitabine (CAP)-based chemoradiation (CRT) for locally advanced pancreatic cancer (LAPC). Here we present ...
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Article
A Review of Thermal Spray Metallization of Polymer-Based Structures
A literature review on the thermal spray deposition of metals onto polymer-based structures is presented. The deposition of metals onto polymer-based structures has been developed to enhance the thermal and el...
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Article
Deposition of Electrically Conductive Coatings on Castable Polyurethane Elastomers by the Flame Spraying Process
Deposition of metallic coatings on elastomeric polymers is a challenging task due to the heat sensitivity and soft nature of these materials and the high temperatures in thermal spraying processes. In this stu...
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Article
Colonisation of dentures by Staphylococcus aureus and MRSA in out-patient and in-patient populations
Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen, and colonisation with this organism can result in localised or systemic infections which may be fatal. One hundred in-patients ad...
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Article
Results of a 7-day aprepitant schedule for the prevention of nausea and vomiting in 5-day cisplatin-based germ cell tumor chemotherapy
The purpose of this study was to determine the efficacy of adding a 7-day aprepitant schedule to a 5HT3 receptor antagonist and dexamethasone for patients with germ cell tumors receiving first-line 5-day cisplati...
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Article
Open AccessRoot cause analysis of hypoglycemic events in critically ill patients
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Article
Resistance of Nanostructured Environmental Barrier Coatings to the Movement of Molten Salts
Corrosion of components in a recovery boiler is a major problem faced by the pulp and paper industry. The superheater tubes become severely corroded due to the presence of sulfidic gases in the boiler and molt...
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Article
Bactericidal Performance of Flame-Sprayed Nanostructured Titania-Copper Composite Coatings
A large concern surrounding stainless steel surfaces is the ability of bacteria to grow and attach to them quite easily. One possible solution to destroy these pathogens is to coat surfaces with a biocidal age...
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Article
Ablation of AMP-activated protein kinase α1 and α2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo
AMP-activated protein kinase (AMPK) is an evolutionarily conserved enzyme and a target of glucose-lowering agents, including metformin. However, the precise role or roles of the enzyme in controlling insulin s...
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Article
Bactericidal Effects of HVOF-Sprayed Nanostructured TiO2 on Pseudomonas aeruginosa
Titanium dioxide (TiO2) has been shown to exhibit photocatalytic bactericidal activity. This preliminary study focused on examining the photocatalytic activity of high-velocity oxy-fuel (HVOF) sprayed nanostructu...
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Article
Reduced-intensity conditioning for severe aplasia using fludarabine and CY followed by infusion of ex vivo T-cell-depleted grafts leads to excellent engraftment and absence of GVHD
We studied the outcome of individuals with aplastic anaemia (AA) who received reduced-intensity conditioning followed by the infusion of stem cell grafts that had been T-cell depleted ex vivo with alemtuzumab. Co...
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Article
New experimental method for the determination of single-component isotherms: an application of the flow-rate retention time
In this paper, we investigate adsorption of a single component (refrigerant) from the variation in the flow rate leaving the column. This requires evaluation of the flow-rate retention time—a measure of the ne...
