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  1. No Access

    Article

    Integrating developmental signals: a Hippo in the (path)way

    The Hippo pathway, a signaling cascade that controls cell cycle progression, apoptosis and cell differentiation, has emerged as a fundamental regulator of many physiological and pathological processes. Recent ...

    A Mauviel, F Nallet-Staub, X Varelas in Oncogene (2012)

  2. Article

    Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients

    As a component of the apoptosome, a caspase-activating complex, Apaf-1 plays a central role in the mitochondrial caspase activation pathway of apoptosis. We report here the identification of a novel Apaf-1 int...

    V Piddubnyak, P Rigou, L Michel, J-C Rain, O Geneste… in Cell Death & Differentiation (2007)

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    Article

    Physical and functional cooperation between AP-1 and β-catenin for the regulation of TCF-dependent genes

    Stabilization of cytoplasmic β-catenin is a hallmark of a variety of cancers. The stabilized β-catenin is able to translocate to the nucleus, where it acts as a transcriptional activator of T-cell factor (TCF)-re...

    K Toualbi, M C Güller, J-L Mauriz, C Labalette, M-A Buendia, A Mauviel… in Oncogene (2007)

  4. No Access

    Article

    Mitogen- and stress-activated protein kinase 1 is critical for interleukin-1-induced, CREB-mediated, c-fos gene expression in keratinocytes

    c-fos, which encodes a transcription factor of the AP-1 family, is a prototypical immediate-early gene induced by a number of proinflammatory cytokines including interleukin-1 (IL-1), the latter being an importan...

    M Schiller, M Böhm, S Dennler, J M Ehrchen, A Mauviel in Oncogene (2006)

  5. No Access

    Article

    Modulation of extracellular matrix metabolism in rabbit articular chondrocytes and human rheumatoid synovial cells by the non-steroidal anti-inflammatory drug etodolac. I: Collagen synthesis

    Cultures of human rheumatoid synovial cells and rabbit articular chondrocytes were exposed to various concentrations of Etodolac (from 0.01 to 10 μg/ml) in presence or absence of 500 pg/ml (5 U/ml) human recom...

    A. Mauviel, F. Redini, G. Loyau, J. -P. Pujol in Agents and Actions (1990)

  6. No Access

    Article

    Modulation of extracellular matrix metabolism in rabbit articular chondrocytes and human rheumatoid synovial cells by the non-steroidal anti-inflammatory drug etodolac. II: Glycosaminoglycan synthesis

    The effect of Etodolac on glycosaminoglycan (GAG) synthesis by human synovial cells and rabbit articular chondrocytes in culture was studied at doses ranging from 0.01 to 10 μg/ml.

    F. Redini, A. Mauviel, G. Loyau, J. -P. Pujol in Agents and Actions (1990)