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Article
Open AccessAn activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina
Recent studies on the endoplasmic reticulum stress have shown that the unfolded protein response (UPR) is involved in the pathogenesis of inherited retinal degeneration caused by mutant rhodopsin. However, the...
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Article
Open AccessDerivation of neural stem cells from an animal model of psychiatric disease
Several psychiatric and neurological diseases are associated with altered hippocampal neurogenesis, suggesting differing neural stem cell (NSC) function may play a critical role in these diseases. To investiga...
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Article
Open AccessDetection of an immature dentate gyrus feature in human schizophrenia/bipolar patients
Hippocampus-associated cognitive impairments are a common, highly conserved symptom of both schizophrenia (SCZ) and bipolar disorder (BPD). Although the hippocampus is likely an impacted region in SCZ/BPD pati...
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Chapter
Creep and Static Fatigue of Magnesia-Partially-Stabilized Zirconia at Room Temperature
Room temperature creep tests under uniaxial loading have been done on two batches of thermal shock grade MgO-partially-stabilized zirconia. Transient creep was observed at stresses between 175 and 280MPa with ...