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  1. Article

    Open Access

    Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer

    The transforming growth factor-beta (TGF- β) pathway has been implicated in proliferation, migration and invasion of various cancers. Endoglin is a TGF-β accessory receptor that modulates signalling. We identifie...

    K O’Leary, A Shia, F Cavicchioli, V Haley, A Comino, M Merlano… in British Journal of Cancer (2015)

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  2. Article

    Open Access

    NT5E CpG island methylation is a favourable breast cancer biomarker

    Relapse risk assessment and individual treatment recommendations remain suboptimal for breast cancer patients. In the light of existing preclinical and clinical data, we studied NT5E (5′-nucleotidase, ecto) expre...

    C Lo Nigro, M Monteverde, S Lee, L Lattanzio, D Vivenza… in British Journal of Cancer (2012)

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  3. Article

    Open Access

    High frequency of complex TP53 mutations in CNS metastases from breast cancer

    Brain metastasis from breast cancer is usually associated with a poor prognosis and early death. Alteration of p53 may contribute to malignant progression by abrogation of apoptosis induced by oncogene activat...

    C Lo Nigro, D Vivenza, M Monteverde, L Lattanzio, O Gojis… in British Journal of Cancer (2012)

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  4. No Access

    Article

    Prolonged survival in poor-risk diffuse large B-cell lymphoma following front-line treatment with rituximab-supplemented, early-intensified chemotherapy with multiple autologous hematopoietic stem cell support: a multicenter study by GITIL (Gruppo Italiano Terapie Innovative nei Linfomi)

    A prospective multicenter program was performed to evaluate the combination of rituximab and high-dose (hd) sequential chemotherapy delivered with multiple autologous peripheral blood progenitor cell (PBPC) su...

    C Tarella, M Zanni, M Di Nicola, C Patti, R Calvi, A Pescarollo, V Zoli… in Leukemia (2007)

  5. No Access

    Article

    Cell proliferation indices, morphometry and DNA flow cytometry provide objective criteria for distinguishing low and high grade bladder carcinomas

    Argyrophilic nucleolar organizer region (Ag-NOR) analysis, proliferating cell nuclear antigen (PC-NA/PC10) and MIB-1 immunohistochemistry, nuclear morphometry and DNA flow cytometry have been performed on form...

    A. Pich, L. Chiusa, R. Navone, A. Comino in Virchows Archiv (1994)