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Article
Impact of allogeneic stem cell transplantation on thyroid function
Primary hypothyroidism is a main endocrine complication after allogeneic stem cells transplantation (allo-SCT) in children, but in adults data on post-SCT hypothyroidism are limited. The aims of this observati...
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Article
Long-term follow-up of allogeneic stem cell transplantation in relapsed/refractory Hodgkin lymphoma
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Article
Open AccessSuccessful management of chronic disseminated candidiasis in hematologic patients treated with high-dose liposomal amphotericin B: a retrospective study of the SEIFEM registry
Chronic disseminated candidiasis (CDC) is a complication of Candida infection in immunocompromised patients, involving the liver and spleen, and rarely other organs. The aim of the study is to identify the best a...
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Article
The reversed halo sign as the initial radiographic sign of pulmonary zygomycosis
Zygomycosis is an emerging fungal infection that is associated with high mortality in hematological patients and stem cell transplantation (SCT) recipients. Radiology—computed tomography (CT) imaging in partic...
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Article
Significance of CTLA-4 and CD14 genetic polymorphisms in clinical outcome after allogeneic stem cell transplantation
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Article
Efficacy of caspofungin as secondary prophylaxis in patients undergoing allogeneic stem cell transplantation with prior pulmonary and/or systemic fungal infection
Transplanted patients with a history of invasive fungal infection (IFI) are at high risk of develo** relapse and fatal complications. Eighteen patients affected by hematological malignancies and a previous I...
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Article
Impact of marrow unrelated donor search duration on outcome of children with acute lymphoblastic leukemia in second remission
We analyzed the outcome of 167 consecutive children with second CR acute lymphoblastic leukemia (ALL), for whom an unrelated donor (UD) search was activated between 1989 and 1998 at a median time of 2 months a...
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Article
Transplant-related toxicity and mortality: an AIEOP prospective study in 636 pediatric patients transplanted for acute leukemia
Hematopoietic stem cell transplantation can cure high-risk acute leukemia (AL), but the occurrence of non-leukemic death is still high. The AIEOP conducted a prospective study in order to assess incidence and ...
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Article
Safety profile of mycophenolate mofetil: a response
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Article
Impact of thrombotic thrombocytopenic purpura on leukemic children undergoing bone marrow transplantation
Thrombotic thrombocytopenic purpura (TTP) has emerged as one of the main transplant-related complications over the last 15 years. The current study defines the incidence and the risk factors for the occurrence...
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Article
Cytotoxic T lymphocyte precursor frequency as a predictor of acute graft-versus-host disease in bone marrow transplantation from HLA-identical siblings
the measurement of precursor frequencies of donor anti-recipient cytotoxic t lymphocytes (ctl-p) has been shown to predict the incidence and the severity of acute graft-versus-host disease (agvhd) in unrelated...
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Article
Mycophenolate mofetil (MMF) as therapy for refractory chronic GVHD (cGVHD) in children receiving bone marrow transplantation
Mycophenolate mofetil (MMF) is an alternative immunosuppressant which inhibits the proliferation of T and B lymphocytes. The purpose of the present study was to evaluate the safety and efficacy of MMF as salva...
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Chapter
Autologous Peripheral Blood Stem Cell Transplantation in Childhood Metastatic Osteosarcoma
Over the past few years the outcome of patients with high grade osteosarcoma (OST) improved dramatically, with survival rates rising from 15% up to 70% [1]. The relatively large series of subjects reported by ...
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Chapter
Autologous Peripheral Blood Stem Cell Transplantation in Childhood Metastatic Osteosarcoma
Over the past few years the outcome of patients with high grade osteosarcoma (OST) has improved dramatically with survival rates rising from 15% up to 70% [1]. The relatively large series of subjects reported ...
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Article
Analysis of early infectious complications in pediatric patients undergoing bone marrow transplantation
The purpose of the present study was to analyze the characteristics of infectious complications occurring during the first 100 days after bone marrow transplantation (BMT) in a cohort of 123 pediatric patient...
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Article
Long-term persistence of hemopoietic chimerism following sex-mismatched bone marrow transplantation
Fifty-eight samples of bone marrow (31), whole peripheral blood (8) and separated fractions of circulating mononuclear (11) and polymorphonuclear (8) cells from 18 male patients, transplanted for hematological...
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Article
Etoposide-containing regimens with autologous bone marrow transplantation in children with malignant brain tumors
Despite improvements in neurosurgical and neuroradiotherapeutic techniques, children with malignant brain tumors have a dismal prognosis. In an attempt to improve the efficacy of cytotoxic therapy, dose intens...
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Article
Second allogeneic bone marrow transplantation in acute leukemia: a multicenter study from the Gruppo Italiano Trapianto Di Midollo Osseo (GITMO)
Thirty-eight second allogeneic bone marrow transplants (BMT) for acute leukemia relapsed after first BMT were performed in 13 Italian centers between 1987 and 1994. Twenty-one patients had acute myelogenous le...
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Article
Bone marrow transplantation in Hunter syndrome