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  1. No Access

    Article

    Prognostic value of monitoring a candidate immunophenotypic leukaemic stem/progenitor cell population in patients allografted for acute myeloid leukaemia

    C Bradbury, A E Houlton, S Akiki, R Gregg, M Rindl, J Khan, J Ward, N Khan… in Leukemia (2015)

  2. No Access

    Article

    Copeptin and arginine vasopressin at high altitude: relationship to plasma osmolality and perceived exertion

    A diuresis is a key part of acclimatisation to high altitude (HA). Arginine vasopressin (AVP) is a hormone involved in salt and water balance and may potentially have a role in the development of altitude illn...

    A. J. Mellor, C. J. Boos, S. Ball, A. Burnett… in European Journal of Applied Physiology (2015)

  3. No Access

    Article

    EMMEL: a framework for historical manuscript analysis and presentation

    In this paper, a generic framework for historical manuscript image and data processing, visualisation and analysis is introduced with a focus on the modelling of manuscript metadata underpinning the interactio...

    Y. Liang, R. M. Guest, M. C. Fairhurst… in Universal Access in the Information Society (2014)

  4. No Access

    Article

    Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia

    Epigenetic therapies demonstrate significant clinical activity in acute myeloid leukemia (AML) and myelodysplasia (MDS) and constitute an important new class of therapeutic agents. However hematological respon...

    C Craddock, L Quek, N Goardon, S Freeman, S Siddique, M Raghavan, A Aztberger… in Leukemia (2013)

  5. Article

    Open Access

    Analysis of the interaction of induction regimens with p-glycoprotein expression in patients with acute myeloid leukaemia: results from the MRC AML15 trial

    Retrospective analyses in non-randomised cohorts suggest that regimens containing fludarabine/Ara C and/or idarubicin/ara C may be more effective than daunorubicin/AraC (DA)-containing regimens in cases of acu...

    M Pallis, R Hills, P White, M Grundy, N Russell, A Burnett in Blood Cancer Journal (2011)

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  6. No Access

    Article

    Fludarabine phosphate and melphalan: a reduced intensity conditioning regimen suitable for allogeneic transplantation that maintains the graft versus malignancy effect

    Reduced intensity conditioning (RIC) for allogeneic stem cell transplantation allows stable donor cell engraftment with the maintenance of a graft versus malignancy effect. Many different regimens exist employ...

    R K Dasgupta, S Rule, P Johnson, J Davies, A Burnett… in Bone Marrow Transplantation (2006)

  7. Article

    Open Access

    Gene expression fingerprint of uterine serous papillary carcinoma: identification of novel molecular markers for uterine serous cancer diagnosis and therapy

    Uterine serous papillary cancer (USPC) represents a rare but highly aggressive variant of endometrial cancer, the most common gynecologic tumour in women. We used oligonucleotide microarrays that interrogate t...

    A D Santin, F Zhan, S Cane', S Bellone, M Palmieri, M Thomas… in British Journal of Cancer (2005)

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  8. No Access

    Article

    Post-Younger Dryas climate interval linked to circumpolar vortex variability: isotopic evidence from Fayetteville Green Lake, New York

    The late-Glacial/Holocene transition in the North Atlantic-European sectors has long been known to be a period of rapid climate change. There is, however, a continued need for acquiring and develo** paleocli...

    M. Kirby, W. Patterson, H. Mullins, A. Burnett in Climate Dynamics (2002)

  9. No Access

    Article

    Identification of PML/RARα rearrangements in suspected acute promyelocytic leukemia using fluorescence in situ hybridization of bone marrow smears: a comparison with cytogenetics and RT-PCR in MRC ATRA trial patients

    S Iqbal, D Grimwade, A Chase, A Goldstone, A Burnett, JM Goldman, D Swirsky in Leukemia (2000)

  10. No Access

    Article

    What happens subsequently in AML when cytogenetic abnormalities persist at bone marrow harvest? Results of the 10th UK MRC AML Trial

    Cytogenetic analysis performed at diagnosis is widely recognised to provide one of the most valuable prognostic indicators in AML. Yet any role for this technique in residual disease assessment, particularly i...

    D Grimwade, H Walker, F Oliver, K Wheatley, R Clack… in Bone Marrow Transplantation (1997)

  11. No Access

    Chapter

    Administering Rule Development in Rule-based Expert Systems

    One recommended approach to the building of expert systems is to start with a very simple system and to expand the level of detail as the system evolves. With this approach there is the practical problem of or...

    P. N. Finlay, Malcolm King, A. Burnett in Artificial Intelligence in Operational Research (1992)

  12. No Access

    Article

    Administering Rule Development in Rule-Based Expert Systems

    One recommended approach to the building of expert systems is to start with a very simple system and to expand the level of detail as the system evolves. With this approach there is the practical problem of or...

    P. N. Finlay, Malcolm King, A. Burnett in Journal of the Operational Research Society (1989)

  13. No Access

    Chapter

    Analysis of Rejection in HLA Matched T-Depleted Bone Marrow Transplants

    In February 1984 a collaborative trial was begun using the Royal Free (RF) cocktail of MBG6 and RFT8 monoclonal antibodies to T-deplete donor marrow for allogeneic BMT for leukaemia. The trial followed the suc...

    J. Patterson, H. G. Prentice, M. Gilmore, H. Blacklock… in 11th Annual meeting of the EBMT (1985)