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    Chapter

    Epigenetic Causes of Obesity

    Obesity is a multifactorial disorder in which genetics, epigenetics and the environment all act and interact with each other. Through a number of investigative techniques, including linkage analysis, genome-wi...

    Özlem Naciye Şahin, Samim Ozen in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Breast Milk and Leptin Resistance

    Leptin, an endocrine signalling molecule released by fat tissue in proportion to the body fat mass, was discovered in 1994. It is a protein with a molecular mass of 160 kDa. The investigative focus following d...

    Özlem Naciye Şahin, Muhittin Abdülkadir Serdar in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Maternal PUFA Supplementation and Epigenetic Influences on Fat Tissue

    Brown adipose tissue (BAT) has the unique ability amongst fat cells of generating heat without causing muscular movement (i.e. shivering). It achieves this by converting surplus chemical energy into heat via U...

    Özlem Naciye Şahin, Aysel Özpınar in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Programming Molecules in Early Life

    Children whose mothers suffered from obesity, diabetes mellitus, or who had feeding difficulties face an increased risk of metabolic disorders, research has shown [1, 2]. Furthermore, being bottle fed or start...

    Özlem Naciye Şahin, Despina D. Briana in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    The Metabolome of Breast Milk and Its Potential Long-Term Effects on the Child

    Current recommendations suggest that the optimal way to feed a neonate is by breastfeeding alone. Human breast milk supplies the complete nutritional requirements of the rapidly growing and develo** infant u...

    Özlem Naciye Şahin, Despina D. Briana in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Gestational Diabetes and Variety in the Composition of Breast Milk

    Diabetes commonly occurs in pregnant women and may cause a number of complications both for the mother and the child, including in the neonatal period. The effects that abnormal maternal metabolism may have on...

    Özlem Naciye Şahin, Gian Carlo Di Renzo in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    The Effects of Metabolic Alteration on Embryonic Stem Cells

    Stem cells exist in multicellular organisms as a reservoir of precursor cells which are pluripotent and can renew themselves multiple times. More differentiated cell types develop from these stem cells. In the...

    Özlem Naciye Şahin, Muhittin Abdülkadir Serdar in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Breast Milk Proteases

    The proteins contained in milk carry out a broad array of complicated biological functions. Some proteins in milk have one function in their intact form, whilst also containing a sequence of latent function th...

    Özlem Naciye Şahin, Despina D. Briana in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Human Milk Composition: Nutrients and Bioactive Factors

    It is widely accepted that the ideal way for a human infant to be nourished up to the age of 6 months is exclusive breastfeeding. Thereafter, breastfeeding with additional sources of nutrition is suitable up t...

    Senem Alkan Özdemir, Özlem Naciye Şahin in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    The Evolution and Genomic Aspects of Milk

    Lactation can be defined as a process by which milk is secreted in large amounts by mammary glands in order to nourish the organism’s offspring. It plays a key role in the reproductive strategy of mammals, so ...

    Özlem Naciye Şahin, Gian Carlo Di Renzo in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Breast Milk Oligosaccharides

    Oligosaccharides are polymeric molecules typically consisting of between three and around ten monosaccharide subunits. Human breast milk differs from that found in the majority of mammalian species by virtue o...

    Özlem Naciye Şahin, Aysel Özpınar in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Genetic Causes of Obesity and Bioactive Substances

    Obesity has many different causes. Although rates of obesity are higher in developed countries, its incidence has recently undergone a sharp rise in develo** countries [1, 2]. Unless the current trend alters...

    Özlem Naciye Şahin, Samim Ozen in Breastfeeding and Metabolic Programming (2023)

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    Book

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    Chapter

    The Part Breast Milk Plays in Epigenetic Programming

    For mammals, following birth, the source of their entire nutrition is milk. Milk provides a transition between placental nutrition and an adult diet. Weaning is the stage of moving onto an adult diet. Evolutio...

    Özlem Naciye Şahin in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    The Infant–Mother Molecular Conversation Involving Breast Milk mRNA

    In mammalian species, there is an ongoing biological dialogue between the mother and offspring from the moment the blastocyst first implants up to the end of breastfeeding. In utero, signals pass via the place...

    Özlem Naciye Şahin, Despina D. Briana in Breastfeeding and Metabolic Programming (2023)

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    Chapter

    Complementary Medicine Products for Use in Pregnancy and the Postpartum Period

    The utilisation of complementary and alternative medical (CAM) products during pregnancy has been addressed by a number of reviews of the scientific literature, although these are limited in extent [1–3]. Ther...

    Atakan Özturan, Sevilay Aynacı in ENT Diseases: Diagnosis and Treatment duri… (2022)

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    Chapter

    Principles of Allergy Skin Testing

    For the diagnosis of allergic rhinitis (AR), the allergen-specific IgE is assumed to be the factor responsible for eliciting inflammation and the symptoms. Therefore, the objective of the diagnostic test is to...

    Özlem Naciye Şahin, Cemal Cingi, Jennifer Derebery in All Around the Nose (2020)