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Article
Efficacy and safety of dabigatran and rivaroxaban in atrial fibrillation patients with impaired liver function: a multicenter retrospective cohort study
The efficacy and safety of direct oral anticoagulants (DOACs) in atrial fibrillation (AF) patients with impaired liver function (ILF) have not been sufficiently studied. The aim of this study was to evaluate t...
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Article
MgO-Modified Activated Carbon Fibers for Enhanced Adsorption of Toluene: Efficiency and Mechanism
To enhance the surface functionalities of activated carbon fiber (ACF), the impregnation and high-temperature calcination methods were utilized to effectively load magnesium oxide on ACF. Dynamic adsorption te...
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Article
Significantly enhanced thermostability and inhibitory resistance of Aspergillus usamii xylanase by modifying its N-terminus and thumb regions
To improve the inhibitory insensitivity towards Aspergillus usamii E001 GH11F xylanase (Auxyn11A) towards xylanase inhibitor protein (XIP-I), and Triticum aestivum xylanase inhibitor (TAXI-I) the site-directed mu...
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Article
Diverse amdoparvoviruses infection of farmed Asian badgers (Meles meles)
Amdoparvoviruses infect various carnivores, including mustelids, canids, skunks, and felids. Aleutian mink disease virus (AMDV) belongs to the prototypical species Amdoparvovirus carnivoran1. Here, we identified ...
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Article
Open AccessDyadic effects of financial toxicity and social support on the fear of cancer recurrence in breast cancer patients and caregivers: an actor–partner interdependence mediation model
In this study, the actor–partner interdependence mediation model (APIMeM) was applied to breast cancer patients and their caregivers to assess the factors that affect the fear of cancer recurrence. In particul...
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Article
Open AccessThe chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis
Synovial tissue inflammation is a hallmark of rheumatoid arthritis (RA). Recent work has identified prominent pathogenic cell states in inflamed RA synovial tissue, such as T peripheral helper cells; however, ...
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Article
Cloning and characterization of a novel mesophilic xylanase gene Fgxyn3 from Fusarium graminearum Z-1
In order to search for high specific activity and the resistant xylanases to XIP-I and provide more alternative xylanases for industrial production, a strain of Fusarium graminearum from Triticum aestivum grains ...
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Article
Open AccessComprehensive analysis of T-cell regulatory factors and tumor immune microenvironment in stomach adenocarcinoma
Gastric cancer (GC) is one of the most prevalent malignant tumors worldwide and is associated with high morbidity and mortality rates. However, the specific biomarkers used to predict the postoperative prognos...
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Article
MPC-based Lateral Motion Control for Autonomous Vehicles Through Serially Cascaded Discretization Method Considering Path Preview
Autonomous vehicles have gained popularity over the past few years. In this paper, an MPC-based lateral motion controller for autonomous vehicles through serially cascade discretization method is developed. A ...
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Article
Open AccessMetformin normalizes mitochondrial function to delay astrocyte senescence in a mouse model of Parkinson’s disease through Mfn2-cGAS signaling
Senescent astrocytes play crucial roles in age-associated neurodegenerative diseases, including Parkinson’s disease (PD). Metformin, a drug widely used for treating diabetes, exerts longevity effects and neuro...
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Article
Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles
Translating genome-wide association study (GWAS) loci into causal variants and genes requires accurate cell-type-specific enhancer–gene maps from disease-relevant tissues. Building enhancer–gene maps is essent...
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Article
Efficient intraoral photogrammetry using self-identifying projective invariant marker
The re-measurement of full-arch implant digital impressions is an important step in denture restoration. This paper provides an efficient oral photogrammetry technology using projective invariant marker, appli...
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Article
Open AccessLongitudinal assessment of the relationship between frailty and social relationships among Japanese older adults: a random intercept cross-lagged panel model
This study aimed to explore the bidirectional association between frailty and social relationships in older adults while distinguishing between interpersonal and intrapersonal effects.
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Article
Distributed visual positioning for surgical instrument tracking
In clinical operations, it is crucial for surgeons to know the location of the surgical instrument. Traditional positioning systems have difficulty dealing with camera occlusion, marker occlusion, and environm...
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Article
Temporal feature markers for event cameras
In this paper, a marker and its real-time tracking method are proposed. Different from existing technologies that recognize the markers by spatial event features, which lead to many practical problems, we disc...
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Article
Open AccessMetagenomic next-generation sequencing of plasma cell-free DNA improves the early diagnosis of suspected infections
Metagenomic next-generation sequencing (mNGS) could improve the diagnosed efficiency of pathogens in bloodstream infections or sepsis. Little is known about the clinical impact of mNGS test when used for the e...
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Article
Open AccessFabrication of levofloxacin-loaded porcine acellular dermal matrix hydrogel and functional assessment in urinary tract infection
Bacterial cystitis, a commonly occurring urinary tract infection (UTI), is renowned for its extensive prevalence and tendency to recur. Despite the extensive utilization of levofloxacin as a conventional thera...
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Article
Open AccessSynaptic-like transmission between neural axons and arteriolar smooth muscle cells drives cerebral neurovascular coupling
Neurovascular coupling (NVC) is important for brain function and its dysfunction underlies many neuropathologies. Although cell-type specificity has been implicated in NVC, how active neural information is con...
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Article
Open AccessLaparoscopic hepatectomy for hepatocellular carcinoma in patients with clinically significant portal hypertension: a systematic review and meta-analysis
To compare the effects of laparoscopic hepatectomy (LH) on the short-term and long-term outcomes in hepatocellular carcinoma (HCC) patients with and without clinically significant portal hypertension (CSPH).
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Article
Robotic versus laparoscopic liver resection for liver malignancy: a systematic review and meta-analysis of propensity score-matched studies
How different surgical procedures, including the robotic-assisted liver resection (RLR) and laparoscopic liver resection (LLR), can affect the prognosis of patients with liver malignancies is unclear. Thus, in...
