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Article
COVID-19 in patients with myasthenia gravis: a single-center retrospective study in China
Coronavirus disease 2019 (COVID-19) has been a great concern since 2019. Patients with myasthenia gravis (MG) may be at higher risk of COVID-19 and a more severe disease course. We examined the associations be...
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Article
Decreased retinal vascular density is associated with cognitive impairment in CADASIL: an optical coherence tomography angiography study
This study aimed to assess alterations in retinal vascular density in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) patients using optical coherence tomog...
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Article
ULK1-dependent phosphorylation of PKM2 antagonizes O-GlcNAcylation and regulates the Warburg effect in breast cancer
Pyruvate kinase M2 (PKM2) is a central metabolic enzyme driving the Warburg effect in tumor growth. Previous investigations have demonstrated that PKM2 is subject to O-linked β-N-acetylglucosamine (O-GlcNAc) m...
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Article
A Novel Robust Flexible Minimum Cost Consensus Model with Consensus Granule
In the consensus reaching process of group decision making (GDM), consensus measures do not require the consensus opinions of all decision makers. Meanwhile, unit adjustment cost is one of the important and of...
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Article
Analysis of blood methylation quantitative trait loci in East Asians reveals ancestry-specific impacts on complex traits
Methylation quantitative trait loci (mQTLs) are essential for understanding the role of DNA methylation changes in genetic predisposition, yet they have not been fully characterized in East Asians (EAs). Here ...
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Article
Open AccessConstruction and application of the core competence course training system for infectious disease specialist nurses
This study aims to construct and apply a training course system which was scientific and comprehensive to foster the core competence of infectious disease specialist nurses.
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Open AccessAuthor Correction: Clinical predictors of prognosis in stroke patients after endovascular therapy
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Article
Open AccessPathological findings with vacuoles in anti-mitochondrial antibody-positive inflammatory myopathy
A few patients with inflammatory myopathy showed anti-mitochondrial antibody (AMA) positivity. This study aimed to report the clinical and pathological findings with vacuoles in 3 cases of such patients.
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Article
Crocin Administration Represses Depressive-Like Behaviors in Rats by Targeting the Hippocampal miRNA-99A/FKBP51/PSD-95 Level
We investigated the role of miR-99a in regulating depressant activity by administering crocin in an animal model of chronic unpredictable mild stress (CUMS). A CUMS rat model was built and crocin was intraperi...
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Article
Open AccessThe Association of Metabolic Risk Factors with Advanced Adenomas in Hispanic Patients
Obesity and metabolic syndrome (MetS) have been implicated as rising risk factors for the development of colorectal cancers. A rapid increase in the prevalence of obesity and severe obesity among Hispanic pati...
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Article
Impact of work connectivity behavior after-hours on employees’ unethical pro-family behavior
With the increasing maturity of supportive office technologies and applied software represented by instantaneous communication and online office, work connectivity behavior after-hours has emerged in various i...
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Article
Open AccessClinical and genetic interpretation of uncertain DMD missense variants: evidence from mRNA and protein studies
Pathogenic missense variants in the dystrophin (DMD) gene are rarely reported in dystrophinopathies. Most DMD missense variants are of uncertain significance and their pathogenicity interpretation remains complic...
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Article
Open AccessPLA2G4A and ACHE modulate lipid profiles via glycerophospholipid metabolism in platinum-resistant gastric cancer
Bioactive lipids involved in the progression of various diseases. Nevertheless, there is still a lack of biomarkers and relative regulatory targets. The lipidomic analysis of the samples from platinum-resistan...
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Article
Direct Conversion of Methane to Methanol by CuN3 Supported on Graphene
Reaction mechanisms of direct conversion of methane to methanol (DCMM) catalyzed by single vacancy graphene supported single Cu atoms (Cu/C3-Gr and Cu/N3-Gr) were investigated using first principles calculations,...
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Article
Why and when innovation performance is available: the role of fell responsibility for constructive change and creative self-efficacy
Combining Gen Z and millennial employee groups, the current study aims to explore the mechanism of felt responsibility for constructive change, taking charge and innovation performance based on the theory of p...
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Article
Open AccessCOASY variant as a new genetic cause of riboflavin-responsive lipid storage myopathy
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Article
Open AccessPhotonic neuromorphic architecture for tens-of-task lifelong learning
Scalable, high-capacity, and low-power computing architecture is the primary assurance for increasingly manifold and large-scale machine learning tasks. Traditional electronic artificial agents by conventional...
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Article
A Projection Method Based on Discrete Normalized Dynamical System for Computing C-eigenpairs
The largest C-eigenvalue of piezoelectric tensors determines the highest piezoelectric coupling constant, which reflects the coupling between the elastic and dielectric properties of crystal. Here, a projectio...
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Article
MET exon 14 skip** mutation drives cancer progression and recurrence via activation of SMAD2 signalling
c-Met encoded by the proto-oncogene MET, also known as hepatocyte growth factor (HGF) receptor, plays a crucial role in cellular processes. MET exon 14 skip** alteration (METΔ14EX) is a newly discovered MET ...
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Article
Open AccessA cost-effectiveness analysis of the combination of serplulimab with chemotherapy for advanced esophageal squamous cell carcinoma: insights from the ASTRUM-007 trial
Combined serplulimab and chemotherapy demonstrated improved clinical survival outcomes in patients with advanced esophageal squamous cell carcinoma (ESCC) and PD-L1 combined positive scores (CPS) ≥ 1. The pres...
