99 Result(s)

Article

SRSF9 promotes cell proliferation and migration of glioblastoma through enhancing CDK1 expression

Glioblastoma (GBM) is a highly aggressive and prevalent brain tumor that poses significant challenges in treatment. SRSF9, an RNA-binding protein, is essential for cellular processes and implicated in cancer p...

Chunyuan Luo, Juan He, Yang Yang, Ke Wu… in Journal of Cancer Research and Clinical On… (2024)

Article

Effect of Infusion Set Replacement Intervals on Central Line-Associated Bloodstream Infection in the Intensive Care Unit: Study Protocol of the INSPIRATION Study

The replacement intervals for infusion sets may differ among healthcare institutions, which may have an impact on the occurrence of central line-associated bloodstream infections (CLABSI). Nevertheless, there ...

Dandan Xu, Chang Hu, Jie **ong, Haiyan Huang… in Infectious Diseases and Therapy (2024)

Article

Correction: ROR1-targeting switchable CAR-T cells for cancer therapy

Haiyong Peng, Thomas Nerreter, Katrin Mestermann, Jakob Wachter, **g Chang… in Oncogene (2024)

Article

Expert Consensus on the Clinical Utilization of Ketamine and Its Isomers in Intensive Care Units

Analgesia and sedation are important treatment strategies in the intensive care unit (ICU). Due to the opioid crisis, opioid-sparing medications become the focus of clinical studies. Ketamine and its isomers (...

Zhiyong Peng, Tongwen Sun, ****g Zhang, Haibo Zhang in Intensive Care Research (2024)

Article

A Longitudinal Clinical Trajectory Analysis Examining the Accumulation of Co-morbidity in People with Type 2 Diabetes (T2D) Compared with Non-T2D Individuals

Type 2 diabetes mellitus (T2D) is commonly associated with an increasing complexity of multimorbidity. While some progress has been made in identifying genetic and non-genetic risk factors for T2D, understandi...

Adrian Heald, Rui Qin, Richard Williams, John Warner-Levy… in Diabetes Therapy (2023)

Article

Clinical application of a fixed reference line in the ultrasound quantitative diagnosis of female pelvic organ prolapse

This study explored using an improved ultrasound (US) for quantitative evaluation of the degree of pelvic organ prolapse(POP).

**aojuan Cao, Yuwen Qiu, Zhiyong Peng, Lan Chen, Li Zhou, Anwei Lu… in BMC Medical Imaging (2023)

Article

Polo-like kinase 1 promotes pulmonary hypertension

Pulmonary hypertension (PH) is a lethal vascular disease with limited therapeutic options. The mechanistic connections between alveolar hypoxia and PH are not well understood. The aim of this study was to inve...

Rongrong Chen, Hongfei Wang, Cuiting Zheng, **yu Zhang, Li Li… in Respiratory Research (2023)

Article

Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function: implication of miRNAs and microvesicles

Vascular hyporeactivity and leakage are key pathophysiologic features that produce multi-organ damage upon sepsis. We hypothesized that pericytes, a group of pluripotent cells that maintain vascular integrity ...

Zi-Sen Zhang, Yi-Yan Liu, Shuang-Shuang He, Dai-Qin Bao… in Military Medical Research (2023)

Article

Leukemogenic SHP2 mutations lead to erythropoietin independency of HCD-57 cells: a novel model for preclinical research of SHP2-mutant JMML

Leukemogenic SHP2 mutations occur in 35% of patients with juvenile myelomonocytic leukemia (JMML), a rare but fatal hematopoietic malignancy without representative cell models, which are urgently needed to inv...

Yuming Zhao, Chunxiao He, Dengyang Zhang, Yao Guo… in Experimental Hematology & Oncology (2023)

Article

The safety and efficacy of mesenchymal stromal cells in ARDS: a meta-analysis of randomized controlled trials

Mesenchymal stromal cells (MSC) have shown potential efficacy in both animal and human trials of acute respiratory distress syndrome (ARDS). Especially during the COVID-19 pandemic, MSC was intensely studied f...

Fengyun Wang, Yiming Li, Bingqing Wang, Jianguo Li, Zhiyong Peng in Critical Care (2023)

Article

COVID-19 Vaccination and Diabetes Mellitus: How Much Has It Made a Difference to Outcomes Following Confirmed COVID-19 Infection?

Since early 2020 the whole world has been challenged by the SARS-CoV-2 virus (COVID-19), its successive variants and the associated pandemic caused. We have previously shown that for people living with type 2 ...

Adrian H. Heald, David A. Jenkins, Richard Williams… in Diabetes Therapy (2023)

Article

Diagnostic pitfalls: a case of prostate cancer and rectal cancer accompanied by prostate cancer invasion of the rectum

Case of double primary cancer of the prostate and rectum is rare, prostate cancer involving the postoperative intestinal anastomotic mucosal tissue is even rarer.

Qiongxian Long, Ji Wu, Yong Peng, Xuqian Zhang, … in Diagnostic Pathology (2022)

Article

Application of Machine Learning for Clinical Subphenotype Identification in Sepsis

Sepsis is a heterogeneous clinical syndrome. Identification of sepsis subphenotypes could lead to allowing more precise therapy. However, there is a lack of models to identify the subphenotypes in such patient...

Chang Hu, Yiming Li, Fengyun Wang, Zhiyong Peng in Infectious Diseases and Therapy (2022)