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Article
Identification of Differentially Expressed Genes in Lung Tissues of Nickel-Exposed Rats Using Suppression Subtractive Hybridization
Occupational exposure to nickel compound, such as nickel refining, electroplating, and in conjunction with other metals, is harmful to the health, causing respiratory distress, and lung and nasal cancer. In th...
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Article
Molecular characterization of β-lactam-resistant Escherichia coli isolated from Fu River, China
The present study aims to demonstrate the β-lactam resistance phenotypes and genotypes of Escherichia coli isolates from the Fu River in Chengdu, southwestern China. We obtained 108 E. coli isolates from nine sam...
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Article
A single nucleotide polymorphism at the Vrn-D1 promoter region in common wheat is associated with vernalization response
Facultative wheat varieties adapt to a particular environment. But the molecular basis for the facultative growth habit is not clear relative to winter and spring growth habit. Two sets of wheat varieties were...
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Article
Isolation and Characterization of a Novel Noncoding RNA from Nickel-Induced Lung Cancer
Noncoding RNAs have drawn significant attention in carcinogenesis. In this study, we identified a novel gene named nickel-related gene1 (NRG1) associated with nickel-induced cancer. By using rapid amplificatio...
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Article
The Alteration of MiR-222 and Its Target Genes in Nickel-Induced Tumor
Nickel is an important kind of metal and a necessary trace element in people’s production and livelihood; it is also a well-confirmed human carcinogen. In the past few years, researchers did a large number of ...
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Article
Effects of wet and dry seasons on the aquatic bacterial community structure of the Three Gorges Reservoir
This study investigated effects of wet and dry seasons on the bacterial community structure of the Three Gorges Reservoir by using denaturing gradient gel electrophoresis analysis of the PCR-amplified bacteria...
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Article
Pluripotent-related gene expression analyses in single porcine recloned embryo
The developmental ability among embryos produced by three different techniques were examined: there were no significant differences in the developmental rate in porcine embryos produced by in vitro fertilizati...
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Article
Extending the linker region increases the activity of the Bacillus subtilis cellulase CelI15
To investigate the effect of the linker region (LR) on the enzymatic activity, stability, and flexibility of Bacillus subtilis cellulase CelI15, six mutants were constructed that contained increasing numbers of t...
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Article
Artificial induction of genetic competence in Bacillus amyloliquefaciens isolates
To induce natural genetic competence in Bacillus amyloliquefaciens isolates through overexpression of the master regulator, ComK, from B. subtilis (ComK Bsu ).
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Article
Development and application of a T7 RNA polymerase-dependent expression system for antibiotic production improvement in Streptomyces
To develop a reliable and easy to use expression system for antibiotic production improvement of Streptomyces.
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Article
Pm61: a recessive gene for resistance to powdery mildew in wheat landrace Xuxusanyuehuang identified by comparative genomics analysis
A single recessive powdery mildew resistance gene Pm61 from wheat landrace Xuxusanyuehuang was mapped within a 0.46-cM genetic interval spanning a 1.3-Mb interval of the genomic region of chromosome arm 4AL.
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Article
Fine map** of the wheat powdery mildew resistance gene Pm52 using comparative genomics analysis and the Chinese Spring reference genomic sequence
A high-resolution genetic linkage map was constructed using the comparative genomics analysis approach and the wheat reference genome, which placed wheat powdery mildew resistance gene Pm52 in a 0.21-cM genetic i...
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Article
Neural Differentiation of Mouse Neural Stem Cells as a Tool to Assess Developmental Neurotoxicity of Drinking Water in Taihu Lake
In this study, we used neural stem cells (NSCs) as a toxicology tool to assess the potential developmental neurotoxicity of drinking water from Taihu Lake. We found that the condensed drinking water could inhi...
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Article
Identification and characterization of an acetyl esterase from Paenibacillus sp. XW-6-66 and its novel function in 7-aminocephalosporanic acid deacetylation
To obtain a new acetyl esterase from Paenibacillus sp. XW-6-66 and apply the enzyme to 7-aminocephalosporanic acid (7-ACA) deacetylation.
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Article
Germplasms, genetics and genomics for better control of disastrous wheat Fusarium head blight
Fusarium head blight (FHB), or scab, for its devastating nature to wheat production and food security, has stimulated worldwide attention. Multidisciplinary efforts have been made to fight against FHB for a lo...
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Article
Nephrotoxicity Profile of Cadmium Revealed by Proteomics in Mouse Kidney
Cadmium (Cd) is a highly toxic metal and kidney is its main target. However, the molecular effects and associated potential impacts of Cd-accumulated kidney have not been well investigated. In this study, mous...
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Article
Isolation of protein-free chitin spore coats of Nosema ceranae and its application to screen the interactive spore wall proteins
Nosema ceranae is the pathogen of nosemosis in the honey bee, which can bring great economic loss to apiculture. Chitin acts as a major component of the endospore of microsporidia and plays an essential role to f...
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Article
Genetic control of Fusarium head blight resistance in two Yangmai 158-derived recombinant inbred line populations
Stably expressed type I and type II resistance QTL were identified using two Yangmai 158-derived RIL populations, and plant-height and flowering-time QTL intervals detected did not contribute to the FHB resist...
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Article
Corallococcus silvisoli sp. nov., a novel myxobacterium isolated from subtropical forest soil
An orange-pigmented myxobacterium, designated strain c25j21T, was isolated from subtropical forest soil collected from the Chebaling National Nature Reserve in Guangdong Province, China. Phylogenetic analysis bas...
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Article
Open AccessAdvances in the Mechanistic Study of the Control of Oxidative Stress Injury by Modulating HDAC6 Activity
Oxidative stress is defined as an injury resulting from a disturbance in the dynamic equilibrium of the redox environment due to the overproduction of active/radical oxygen exceeding the antioxidative ability ...