43 Result(s)

Article

CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in Anterior Cingulate Cortex

Previous studies have shown that the C-C motif chemokine ligand 2 (CCL2) is widely expressed in the nervous system and involved in regulating the development of chronic pain and related anxiety-like behaviors,...

Huan Guo, Wen-chao Hu, Hang **an, Yun-xin Shi, Yuan-ying Liu… in Molecular Neurobiology (2023)

Article

Shared and Distinct Topographic Alterations of Alpha-Range Resting EEG Activity in Schizophrenia, Bipolar Disorder, and Depression

Rui Xue, **ao**g Li, Jianning Chen, Sugai Liang, Hua Yu… in Neuroscience Bulletin (2023)

Article

Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease

Depression is among the most frequent psychiatric comorbid conditions in Alzheimer disease (AD). However, pharmacotherapy for depressive disorders in AD is still a big challenge, and the data on the efffcacy o...

Meng Zhang, Li-yuan Liu, Yong Xu, Wen-zhi Wang, Nian-zhuang Qiu… in Metabolic Brain Disease (2023)

Article

Longitudinal study of multi-parameter quantitative magnetic resonance imaging in Duchenne muscular dystrophy: hyperresponsiveness of gluteus maximus and detection of subclinical disease progression in functionally stable patients

To describe the disease progression of Duchenne muscular dystrophy (DMD) in the pelvic and thigh muscles over 1-year using multiple-parameter quantitative magnetic resonance imaging (qMRI), and to determine th...

Fei Peng, Huayan Xu, Yu Song, Ke Xu, Shuhao Li, **aotang Cai… in Journal of Neurology (2023)

Article

Isobavachalcone’s Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3

Glioblastoma multiforme (GBM) is the most malignant intracranial tumor with high mortality rates and invariably poor prognosis due to its limited clinical treatments. There is an urgent need to develop new the...

Yueshan Wu, **g Chang, Juanjuan Ge, Kangyan Xu, Quan Zhou… in Molecular Neurobiology (2022)

Article

Combined influence of ABCB1 genetic polymorphism and DNA methylation on aspirin resistance in Chinese ischemic stroke patients

Genetic variants of ABCB1 may affect intestinal absorption of aspirin (ASA). However, it is unclear whether ABCB1 polymorphisms and DNA methylation are associated with ASA efficacy for ischemic stroke. Our aim...

Liyan Xu, Yan Wang in Acta Neurologica Belgica (2022)

Article

Association Study Between Genetic Variation in Whole Mitochondrial Genome and Ischemic Stroke

Mitochondrial DNA (mtDNA) affects the mitochondrial function, which is potentially related to susceptibility to ischemic stroke (IS). However, study on IS genetics by whole mitochondrial genome sequencing has ...

Yingying Luan, Dongzhi Yang, Zhao**g Zhang… in Journal of Molecular Neuroscience (2021)

Article

Nucleoprotein (P40) Binding to 5HT2C Receptors (5HT2CR) is the Key Point in the Pathogenesis of BoDV-1-Infected Hosts

Nucleoprotein (P40) is one of the most important proteins of Borna disease virus 1 (BoDV-1), but which proteins it would bind to in the pathogenesis of BoDV-1-infected hosts is unknown. We used lentivirus LV5-...

Yuanxin Li, Lixin Wang, Xueni Liu, Ying Huang, **aomei Li… in Neurochemical Research (2021)

Article

Down-Regulation of ID2-AS1 Alleviates the Neuronal Injury Induced by 1-Methy1-4-Phenylpyridinium in Human Neuroblastoma Cell Line SH-SY5Y Cells Through Regulating miR-199a-5p/IFNAR1/JAK2/STAT1 Axis

We aimed to illustrate the roles and molecular mechanisms of ID2-AS1 in parkinson’s disease (PD). Methods: qRT-PCR detected the expression of ID2-AS1. CCK-8, LDH release assays the effect of ID2-AS1 knockdown ...

Furong Xu, Hui Wang, Ju Tian, Haiyan Xu in Neurochemical Research (2021)

Article

Circ_0132817 facilitates cell proliferation, migration, invasion and glycolysis by regulating the miR-432-5p/NOL4L axis in neuroblastoma

Neuroblastoma (NB) is one of the most common extracranial solid tumors in children. Circular RNAs (circRNAs) have been shown to be involved in the development of NB. However, the function of circ_0132817 in NB...

Yafei Fang, Yuqian Yao, Kangwei Mao, Yanyan Zhong, Yan Xu in Experimental Brain Research (2021)

Article

3-Hz Postural Tremor in MSA-C and SCA: Revisiting an Old but Underestimated Cerebellar Sign by Posturography

The aim of this study is to evaluate the prevalence and electrophysiological features of 3-Hz postural tremor in multiple system atrophy-cerebellar type and spinocerebellar ataxia. A static posturography exami...

**aodi Li, **ao Lv, Churong Liu, **long Ye, Yan Xu, Gengmao Ma, Zhong Li… in The Cerebellum (2021)

Article

Adjuvant therapy with Astragalus membranaceus for post-stroke fatigue: a systematic review

Post-stroke fatigue (PSF) is a common symptom after stroke and interferes with the rehabilitation. There are limited pharmacological therapies for managing PSF. Astragalus membranaceus (Huangqi) is a frequently u...

Li Xu, **ao-Yan Xu, Xue-Qin Hou, Fu-Gang Wang, Shan Gao… in Metabolic Brain Disease (2020)

Article

Biallelic INTS1 Mutations Cause a Rare Neurodevelopmental Disorder in Two Chinese Siblings

This study presents two Chinese siblings with a rare neurodevelopmental disorder (NDD) caused by biallelic INTS1 mutations and investigates the clinical features of this disease by means of in silico analysis. Tw...

Xuemin Zhang, Yajian Wang, Fang Yang, Jiulai Tang… in Journal of Molecular Neuroscience (2020)