64 Result(s)

Article

CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in Anterior Cingulate Cortex

Previous studies have shown that the C-C motif chemokine ligand 2 (CCL2) is widely expressed in the nervous system and involved in regulating the development of chronic pain and related anxiety-like behaviors,...

Huan Guo, Wen-chao Hu, Hang **an, Yun-xin Shi, Yuan-ying Liu… in Molecular Neurobiology (2023)

Article

Shared and Distinct Topographic Alterations of Alpha-Range Resting EEG Activity in Schizophrenia, Bipolar Disorder, and Depression

Rui Xue, **ao**g Li, Jianning Chen, Sugai Liang, Hua Yu… in Neuroscience Bulletin (2023)

Article

Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease

Depression is among the most frequent psychiatric comorbid conditions in Alzheimer disease (AD). However, pharmacotherapy for depressive disorders in AD is still a big challenge, and the data on the efffcacy o...

Meng Zhang, Li-yuan Liu, Yong Xu, Wen-zhi Wang, Nian-zhuang Qiu… in Metabolic Brain Disease (2023)

Article

Supramaximal resection based on en-bloc technique reduces tumor burden and prolongs survival in primary supratentorial lobar glioblastoma

Resection beyond the contrast-enhanced zone contributed to reduce tumor burden and prolong survival in glioblastomas. The optimal extent of resection (EOR) and how to achieve it are worthy of continuous invest...

Tianshi Que, Guanglong Huang, Jian-er Tan, Peidong Zhang… in Journal of Neuro-Oncology (2023)

Article

Research trends in hypertension associated with obstructive sleep apnea: a bibliometric analysis

The purpose of this study was to systematically analyze the studies of hypertension associated with obstructive sleep apnea to assess the current status and hot spots in this field.

Yirou Niu, Hongwei Cai, Wei Zhou, Haiyan Xu, **aodan Dong… in Sleep and Breathing (2023)

Article

Longitudinal study of multi-parameter quantitative magnetic resonance imaging in Duchenne muscular dystrophy: hyperresponsiveness of gluteus maximus and detection of subclinical disease progression in functionally stable patients

To describe the disease progression of Duchenne muscular dystrophy (DMD) in the pelvic and thigh muscles over 1-year using multiple-parameter quantitative magnetic resonance imaging (qMRI), and to determine th...

Fei Peng, Huayan Xu, Yu Song, Ke Xu, Shuhao Li, **aotang Cai… in Journal of Neurology (2023)

Article

miR-485-5p alleviates obstructive sleep apnea syndrome with hypertension by inhibiting PI3K/AKT signaling pathway via downregulating HIF3A expression

The obstructive sleep apnea syndrome (OSAS) is a risk factor for hypertension. MiRNAs are key regulators in hypertension. However, their roles in OSAS with hypertension remain unclear. This study aimed to clar...

Yan Xu, Tao Hu, Huizhen Ding, Yi Yuan, Rui Chen in Sleep and Breathing (2023)

Article

Elevated systemic immune inflammation level increases the risk of total and cause-specific mortality among patients with chronic kidney disease: a large multi-center longitudinal study

Chronic kidney disease (CKD) is inherently a complex immune-inflammatory condition, and heightened inflammation and immune dysfunction are closely related to an increased risk of death. However, evidence regar...

Wenguang Lai, Yun **e, **aoli Zhao, **ayan Xu, Sijia Yu, Hongyu Lu… in Inflammation Research (2023)

Article

Isobavachalcone’s Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3

Glioblastoma multiforme (GBM) is the most malignant intracranial tumor with high mortality rates and invariably poor prognosis due to its limited clinical treatments. There is an urgent need to develop new the...

Yueshan Wu, **g Chang, Juanjuan Ge, Kangyan Xu, Quan Zhou… in Molecular Neurobiology (2022)

Article

Combined influence of ABCB1 genetic polymorphism and DNA methylation on aspirin resistance in Chinese ischemic stroke patients

Genetic variants of ABCB1 may affect intestinal absorption of aspirin (ASA). However, it is unclear whether ABCB1 polymorphisms and DNA methylation are associated with ASA efficacy for ischemic stroke. Our aim...

Liyan Xu, Yan Wang in Acta Neurologica Belgica (2022)

Article

Association Study Between Genetic Variation in Whole Mitochondrial Genome and Ischemic Stroke

Mitochondrial DNA (mtDNA) affects the mitochondrial function, which is potentially related to susceptibility to ischemic stroke (IS). However, study on IS genetics by whole mitochondrial genome sequencing has ...

Yingying Luan, Dongzhi Yang, Zhao**g Zhang… in Journal of Molecular Neuroscience (2021)

Article

Nucleoprotein (P40) Binding to 5HT2C Receptors (5HT2CR) is the Key Point in the Pathogenesis of BoDV-1-Infected Hosts

Nucleoprotein (P40) is one of the most important proteins of Borna disease virus 1 (BoDV-1), but which proteins it would bind to in the pathogenesis of BoDV-1-infected hosts is unknown. We used lentivirus LV5-...

Yuanxin Li, Lixin Wang, Xueni Liu, Ying Huang, **aomei Li… in Neurochemical Research (2021)