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    Article

    CCL2 Potentiates Inflammation Pain and Related Anxiety-Like Behavior Through NMDA Signaling in Anterior Cingulate Cortex

    Previous studies have shown that the C-C motif chemokine ligand 2 (CCL2) is widely expressed in the nervous system and involved in regulating the development of chronic pain and related anxiety-like behaviors,...

    Huan Guo, Wen-chao Hu, Hang **an, Yun-xin Shi, Yuan-ying Liu in Molecular Neurobiology (2023)

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    Article

    Isobavachalcone’s Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3

    Glioblastoma multiforme (GBM) is the most malignant intracranial tumor with high mortality rates and invariably poor prognosis due to its limited clinical treatments. There is an urgent need to develop new the...

    Yueshan Wu, **g Chang, Juanjuan Ge, Kangyan Xu, Quan Zhou in Molecular Neurobiology (2022)

  3. Article

    Correction to: 3-Hz Postural Tremor in MSA-C and SCA: Revisiting an Old but Underestimated Cerebellar Sign by Posturography

    **aodi Li, **ao Lv, Churong Liu, **long Ye, Yan Xu, Gengmao Ma, Zhong Li in The Cerebellum (2022)

  4. Article

    Open Access

    Astrocyte reactivation in medial prefrontal cortex contributes to obesity-promoted depressive-like behaviors

    Little is known about how the obesogenic environment influences emotional states associated with glial responses and neuronal function. Here, we investigated glial reactivation and neuronal electrophysiologica...

    Gang Yu, Feng Cao, Tingting Hou, Yunsheng Cheng, Benli Jia in Journal of Neuroinflammation (2022)

  5. No Access

    Article

    3-Hz Postural Tremor in MSA-C and SCA: Revisiting an Old but Underestimated Cerebellar Sign by Posturography

    The aim of this study is to evaluate the prevalence and electrophysiological features of 3-Hz postural tremor in multiple system atrophy-cerebellar type and spinocerebellar ataxia. A static posturography exami...

    **aodi Li, **ao Lv, Churong Liu, **long Ye, Yan Xu, Gengmao Ma, Zhong Li in The Cerebellum (2021)

  6. Article

    Open Access

    Bioinformatics analysis of glial inflammatory responses to air pollution

    Chenyu Li, Wei Jiang, Nina Tang, Yan Xu in Journal of Neuroinflammation (2017)

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    Article

    SYD-1 Promotes Multiple Developmental Steps Leading to Neuronal Connectivity

    The establishment of neuronal connectivity requires precise orchestration of multiple developmental steps, including axon specification, axon guidance, selection of synaptic target sites, and development of sy...

    Yan Xu, Christopher C. Quinn in Molecular Neurobiology (2016)

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    Article

    The Pivotal Role of Ca2+ Homeostasis in PBDE-47-Induced Neuronal Apoptosis

    Polybrominated diphenyl ethers (PBDEs) are widely used flame retardants and are ubiquitous in the environment and human tissues. Recent evidence has demonstrated that PBDE-induced neurotoxicity is associated w...

    Shun Zhang, Yihu Chen, Xue Wu, Hui Gao, Rulin Ma, Chunyang Jiang in Molecular Neurobiology (2016)

  9. Article

    Open Access

    Sexually dimorphic outcomes and inflammatory responses in hypoxic-ischemic encephalopathy

    Neonatal hypoxic-ischemic encephalopathy (HIE) is an important cause of motor and cognitive impairment in children. Clinically, male infants are more vulnerable to ischemic insults and suffer more long-term de...

    Mehwish A Mirza, Rodney Ritzel, Yan Xu, Louise D McCullough in Journal of Neuroinflammation (2015)

  10. Article

    Open Access

    Met-CCL5 represents an immunotherapy strategy to ameliorate rabies virus infection

    Infection of rabies virus (RABV) causes central nervous system (CNS) dysfunction and results in high mortality in human and animals. However, it is still unclear whether and how CNS inflammation and immune res...

    Ying Huang, Shaozhuo Jiao, **aoyan Tao, Qing Tang in Journal of Neuroinflammation (2014)

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    Article

    Prefrontal Control of Cerebellum-Dependent Associative Motor Learning

    Behavioral studies have demonstrated that both medial prefrontal cortex (mPFC) and cerebellum play critical roles in trace eyeblink conditioning. However, little is known regarding the mechanism by which the t...

    Hao Chen, Li Yang, Yan Xu, Guang-yan Wu, Juan Yao, Jun Zhang, Zhi-ru Zhu in The Cerebellum (2014)

  12. No Access

    Chapter

    White Matter Injury in Global Cerebral Ischemia

    In chronic cerebral hypoperfusion due to aging, global cerebral ischemia after cardiac arrest, acute and chronic hypoxia in asymptomatic stroke, and diffuse axonal injury after traumatic brain injury, white ma...

    Shinichi Nakao M.D., Ph.D., Yan Xu Ph.D. in White Matter Injury in Stroke and CNS Disease (2014)