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Article
Priming effects by cellulose inputs decrease with warming regardless of the decomposition stages of soil carbon pools
Soil comprises diverse carbon (C) pools undergoing various decomposition stages, each characterized by distinct stability and turnover rates. The response of these C pools to warming with the input of plant re...
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Article
Response of Potato Growth and Yield to Drought Scenarios Based on APSIM-Potato in the Single-Crop** Region in Northern China
As a result of climate warming, the frequency and intensity of droughts have increased. Potato planting and production activities in the single-crop** region in Northern China are affected by drought, which ...
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Article
Open AccessFibronectin mediates activin A-promoted human trophoblast migration and acquisition of endothelial-like phenotype
During human early placentation, a proportion of extravillous trophoblasts (EVTs) migrate to the maternal decidua, differentiating into endovascular EVTs to remodel spiral arteries and ensure the establishment...
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Article
Crosstalk between ferroptosis and macrophages: potential value for targeted treatment in diseases
Ferroptosis is a newly identified form of programmed cell death that is connected to iron-dependent lipid peroxidization. It involves a variety of physiological processes involving iron metabolism, lipid metab...
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Article
Dioscorea composita WRKY5 positively regulates AtSOD1 and AtABF2 to enhance drought and salt tolerances
DcWRKY5 increases the antioxidant enzyme activity and proline accumulation, oppositely, reduces the accumulation of ROS and MDA, through directly activating the genes expression, finally enhances the salt and dro...
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Article
Design, synthesis and mechanism study of novel natural-derived isoquinoline derivatives as antifungal agents
In screening for natural fungicidal leads, two series of novel 3-aryl-isoquinoline derivatives 8 and 9 were designed and synthesized based on sanguinarine, chelerythrine and berberine. Their structures were confi...
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Article
Evaluation of Copper Levels in Dental Calculus of OSF Patients with Chewing Dried Areca-Nut Quids in Hunan Province of Mainland China
Dental calculus is a potential material that can be used for assessing chronic exposure to trace heavy metals in oral cavity as it is a long-term reservoir. The aim of this study was to investigate the correla...
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Article
The effects of dietary supplementation of ginseng stem and leaf saponins on the antioxidant capacity, immune response, and disease resistance of crucian carp, Carassius auratus
This is the first study to explore the positive effects of ginseng stem and leaf saponins (GSLS) on antioxidant capability, immunity, and disease resistance of crucian carp. Seven hundred fifty crucian carps (...
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Article
Open AccessStructural insights of the elongation factor EF-Tu complexes in protein translation of Mycobacterium tuberculosis
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is the second-deadliest infectious disease worldwide. Emerging evidence shows that the elongation factor EF-Tu could be an excellent target for treatin...
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Article
CHANGE-seq reveals genetic and epigenetic effects on CRISPR–Cas9 genome-wide activity
Current methods can illuminate the genome-wide activity of CRISPR–Cas9 nucleases, but are not easily scalable to the throughput needed to fully understand the principles that govern Cas9 specificity. Here we d...
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Article
Nitrogen and phosphorus co-addition stimulates soil respiration in a subtropical evergreen broad-leaved forest
Nutrient availability is a key regulator of soil respiration. Anthropogenic activities have dramatically accelerated the inputs of reactive nitrogen (N) and phosphorous (P) and increased the availability of N ...
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Article
CaMKK1 from Chenopodium album positively regulates salt and drought tolerance in transgenic tobacco
Plants encounter various abiotic stresses during the whole life cycle. The mitogen-activated protein kinase kinase (MAPKK) acts as the convergent point of MAPK cascade in stress signaling pathway, which has no...
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Article
Growth differentiation factor 9 of Megalobrama amblycephala: molecular characterization and expression analysis during the development of early embryos and growing ovaries
Growth differentiation factor 9 (GDF9) is a member of the transforming growth factorβ superfamily and plays an essential role during follicle maturation in mammals. In the present study, the full-length comple...
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Article
Role of alternative sigma factor 54 (RpoN) from Vibrio anguillarum M3 in protease secretion, exopolysaccharide production, biofilm formation, and virulence
The sigma factor σ54 (RpoN) is an important regulator of bacterial response to environmental stresses. Here, we demonstrate the roles of RpoN in Vibrio anguillarum M3 by comparative investigation of physiological...
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Article
Conformational study of protein in some species ofFusarium by FT-IR spectroscopy
A novel method of estimating conformation of protein secondary structure withinFusarium cells under the influence of growth cultures and bodies was studies by Fourier-Transform Infrared (FT-IR) spectroscopy combi...
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Article
Enhanced radioimmunotherapeutic efficacy of a monoclonal antibody cocktail against SMMC-7721 human hepatocellular carcinoma
The improved tumoricidal effect of the radioantibody mixture (“cocktail”) has been reported recently for the treatment of colon tumor. In the present study, we demonstrated the enhanced radioimmunotherapeutic ...
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Article
Regional variation of cancer mortality incidence and its relation to selenium levels in China
The epidemiological relationship between selenium level and age-adjusted human cancer mortality (incidence) was studied in 24 regions located in eight provinces of China. Statistically significant inverse corr...