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  1. No Access

    Article

    Therapeutic Effect of a Novel Nano-Drug Delivery System on Membranous Glomerulonephritis Rat Model Induced by Cationic Bovine Serum

    In order to explore a novel high efficacy drug delivery system for membranous glomerulonephritis (MGN), a complex chronic inflammation, methylprednisolone bovine serum albumin nanoparticles (ME BSA NPs) were d...

    **umei Gai, Zhujun Jiang, Mengqi Liu, Qi Li, Shu Wang, Ting Li in AAPS PharmSciTech (2018)

  2. No Access

    Article

    In vitro and In vivo Studies on a Novel Bioadhesive Colloidal System: Cationic Liposomes of Ibuprofen

    The objective of this study was to develop an ocular drug delivery system built on the cationic liposomes, a novel bioadhesive colloidal system, which could enhance the precorneal residence time, ocular permea...

    **umei Gai, Lizhen Cheng, Ting Li, Dandan Liu, Yanyan Wang in AAPS PharmSciTech (2018)

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    Article

    Aqueous Polymer Dispersion Coating Used for Osmotic Pump Tablets: Membrane Property Investigation and IVIVC Evaluation

    The objective of this study was to investigate the fundamental properties of propranolol hydrochloride osmotic pump tablets coated by aqueous polymer dispersion, simultaneously exploring the in vitro and in vivo ...

    Lizhen Cheng, **umei Gai, Haoyang Wen, Dandan Liu, **n Tang in AAPS PharmSciTech (2018)

  4. No Access

    Article

    Design of a Time-Controlled Pulsatile Release System for Propranolol Using the Dry-Coated Method: In Vitro and In Vivo Evaluation

    The objective of this study was to design a time-controlled pulsatile release (TCPR) system containing propranolol (PNH) as an active pharmaceutical ingredient. Here, the developed dosage forms were coated wit...

    Kai Chen, Yanyan Wang, **umei Gai, Haiying Wang, Yuenan Li in AAPS PharmSciTech (2017)

  5. Article

    Open Access

    A novel pH-sensitive carrier for the delivery of antitumor drugs: histidine-modified auricularia auricular polysaccharide nano-micelles

    The study was aimed to design a novel pH-sensitive carrier to deliver antitumor drugs to increase treatment efficiency. Histidine (His)was used to modify auricularia auricular polysaccharide (AAP) by esterific...

    Yingying Wang, **fei Li, Fen Chen, Lianqun Jia, Qihao Xu in Scientific Reports (2017)