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Article
Open AccessTherapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitis
Mucus injury associated with goblet cell (GC) depletion constitutes an early event in inflammatory bowel disease (IBD). Using single-cell sequencing to detect critical events in mucus dysfunction, we discover ...
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Article
A Multi-objective Apple Leaf Disease Detection Algorithm Based on Improved TPH-YOLOV5
To address the challenge of apple leaf disease target recognition in complex environments, we proposed an improved apple leaf disease detection algorithm based on TPH-YOLOV5. We filtered, supplemented, and enh...
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Article
Hyperspectral classification employing spatial–spectral low rank representation in hidden fields
This paper presents a novel classification method based on spatial–spectral low-rank representation in the hidden field under a Bayesian framework for hyperspectral imagery. The key idea of the method is to si...
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Article
Open AccessCharacterizing immune variation and diagnostic indicators of preeclampsia by single-cell RNA sequencing and machine learning
Preeclampsia is a multifactorial and heterogeneous complication of pregnancy. Here, we utilize single-cell RNA sequencing to dissect the involvement of circulating immune cells in preeclampsia. Our findings re...
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Article
Multi-granularity feature utilization network for cross-modality visible-infrared person re-identification
Cross-modality visible-infrared person re-identification (VI-ReID) aims to recognize images with the same identity between visible modality and infrared modality, which is a very challenging task because it no...
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Article
Free radicals induced ultra-rapid synthesis of N-doped carbon sphere catalyst with boosted pyrrolic N active sites for efficient acetylene hydrochlorination
Activated carbon-supported HgCl2 catalysts have seriously impeded the development of the polyvinyl chloride (PVC) industry due to the sublimation of Hg species and environmental pollution problems. Herein, the te...
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Article
Open AccessTranscriptional expression of CXCL10 and STAT1 in lupus nephritis and the intervention effect of triptolide
This study screened out the key genes associated with the occurrence and development of lupus nephritis (LN) using bioinformatics methods, and then explored the expression of key genes in LN and the inhibitory...
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Chapter and Conference Paper
Research on the Design of Digital Experience of Sichuan Opera Face-Changing Based on Flow Theory
Face-changing is a traditional performance form of Sichuan Opera in which the performer can switch between multiple faces in a short time. Special costumes and props are required for the performance, and the a...
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Chapter and Conference Paper
Develop Cognitive Games for Older People Based on Dynamic Difficulty Adjustment to Motivate Them to Train
The declining cognitive abilities of older adults as they age can affect their quality of life levels. Video games have been shown to have a positive effect on improving the cognitive abilities of older adults...
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Article
Open AccessEfficacy of generic teriparatide and alendronate in Chinese postmenopausal women with osteoporosis: a prospective study
The efficacy of generic teriparatide in improving BMD at lumbar spine in patients with osteoporosis was similar to that of alendronate. It provided a new choice for osteoporosis treatment in Chinese population.
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Article
Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus
Membrane protein efflux pumps confer antibiotic resistance by extruding structurally distinct compounds and lowering their intracellular concentration. Yet, there are no clinically approved drugs to inhibit ef...
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Article
Open AccessKnockdown of PAR2 alleviates cancer-induced bone pain by inhibiting the activation of astrocytes and the ERK pathway
Cancer-induced bone pain (CIBP) is a kind of pain with complex pathophysiology. Proteinase-activated receptor 2 (PAR-2) is involved in CIBP. This study explored the effects of PAR-2 on CIBP rats.
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Article
Fluorescence Determination of Ni2+ Ions Based on a Novel Nano-Platform Derived from Silicon Quantum Dots
Quantum dots generate unique luminescent and chemical properties due to the ultra-small particle sizes. In this contribution, a novel silicon nanoparticles (Si-NPs)-based platform has been established via (3-a...
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Article
Ultra-compact photonic crystal couplers for optical switches based on band-edge resonance
Optical couplers play an important role in optical switches to split or combine light power in a predictable way. We proposed a novel scheme of photonic crystal (PhC) couplers relying on the unique characteris...
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Article
Open AccessThe cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors
Staphylococcus aureus bi-component pore-forming leukocidins are secreted toxins that directly target and lyse immune cells. Intriguingly, one of the leukocidins, Leukocidin AB (LukAB), is found associated with th...
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Article
Stepwise Assembly Protocols for the Rational Design of Lanthanide Functionalized Carbon Dots-Hydrogel and its Sensing Evaluation
Inorganic-organic optical probe based on lanthanide emission will provide a new way for specific applications. In this work, sarcosine and urea are selected as raw materials to synthesize carbon dots with cyan...
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Article
Cross-view kernel collaborative representation classification for person re-identification
Currently, person re-identification (re-ID) has been applied in many public security applications. Yet owing to the big visual appearance changes of the same identity under different views, re-ID still faces m...
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Article
Surface modification via 2-thenoyltrifluoroacetone and the photophysical studies
The precise control of phosphors with well-defined features remains a challenging issue since its property has been closely related to the shape, surface modification and particle size. The studies to develop ...
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Chapter and Conference Paper
Cascaded Convolutional Neural Network for Image Super-Resolution
Image super resolution is an important field of computer research. The current mainstream image super-resolution technology is to use deep learning to mine the deeper features of the image, and then use it for...
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Chapter and Conference Paper
Influence of Big Data Development on Regional Rural Economic Growth
With the help of big data concept and related technology and operation mode, we can further improve the operation efficiency of multiple links such as arable land, sowing, fertilization, harvesting, storage, a...
