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35th Annual Meeting of the European Association for the Study of Diabetes
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Chemical probing reveals insights into the signaling mechanism of inflammasome activation
Caspase-1-mediated IL-1β production is generally controlled by two pathways. Toll-like receptors (TLRs) recognize pathogen-derived products and induce NF-κB-dependent pro-IL-1β transcription; NOD-like receptor...
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Open AccessCloning and expression profiling of the VLDLR gene associated with egg performance in duck (Anas platyrhynchos)
The very low density lipoprotein receptor gene (VLDLR), a member of the low density lipoprotein receptor (LDLR) gene family, plays a crucial role in the synthesis of yolk protein precursors in oviparous species. ...
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Pharmacological mechanisms underlying the antinociceptive and tolerance effects of the 6,14-bridged oripavine compound 030418
To investigate possible pharmacological mechanisms underlying the antinociceptive effect of and tolerance to N-methyl-7α-[(R)-1-hydroxy-1-methyl-3-(thien-3-yl)-propyl]-6,14-endo-ethanotetrahydronororipavine (0304...
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Open AccessPoly (ADP-Ribose) Transferase/Polymerase-1-Deficient Mice Resistant to Age-Dependent Decrease in β-Cell Proliferation
Basal and adaptive β-cell regeneration capacity declines with old age, but the underlying molecular mechanisms remain incompletely understood. Poly (adenosine diphosphate [ADP]-ribose) polymerase 1 (PARP-1) is...
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Open AccessNitrilases in nitrile biocatalysis: recent progress and forthcoming research
Over the past decades, nitrilases have drawn considerable attention because of their application in nitrile degradation as prominent biocatalysts. Nitrilases are derived from bacteria, filamentous fungi, yeast...
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Open AccessPrevalence of metabolic syndrome among urban community residents in China
Metabolic risk factors and abnormalities such as obesity and hypertension are rapidly rising among the Chinese population following China’s tremendous economic growth and widespread westernization of lifestyle...
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Open AccessHigh admission glucose levels increase Fas apoptosis and mortality in patients with acute ST-elevation myocardial infarction: a prospective cohort study
The presence of diabetes and plasma glucose concentration on admission are associated with adverse outcomes after an acute myocardial infarction (AMI), as high glucose can induce vascular endothelial cell apop...
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An investigation into the deformation, movement and coalescence characteristics of water-in-oil droplets in an AC electric field
Drop-drop coalescence is important in electric dehydrators used for oil-water separation in the oil industry. The deformation degree, angle between the electric field and the center line of two drops, effects ...
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Restoration of autophagic flux in myocardial tissues is required for cardioprotection of sevoflurane postconditioning in rats
Sevoflurane postconditioning (SpostC) has been shown to protect the heart from ischemia-reperfusion (I/R) injury. In this study, we examined whether SpostC affected autophagic flux in myocardial tissues that c...
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Brucine suppresses ethanol intake and preference in alcohol-preferring Fawn-Hooded rats
Brucine (BRU) extracted from the seeds of Strychnos nux-vomica L is glycine receptor antagonist. We hypothesize that BRU may modify alcohol consumption by acting at glycine receptors, and evaluated the pharmacody...
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Open AccessmiR-10b is overexpressed in hepatocellular carcinoma and promotes cell proliferation, migration and invasion through RhoC, uPAR and MMPs
Recently, miR-10b is identified as a miRNA highly expressed in many human cancers, promoting cell migration and invasion. However, the specific function of miR-10b in hepatocellular carcinoma (HCC) is unclear ...
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Open AccessDriving ferromagnetic resonance frequency of FeCoB/PZN-PT multiferroic heterostructures to Ku-band via two-step climbing: composition gradient sputtering and magnetoelectric coupling
RF/microwave soft magnetic films (SMFs) are key materials for miniaturization and multifunctionalization of monolithic microwave integrated circuits (MMICs) and their components, which demand that the SMFs sho...
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Open AccessBetter short-term efficacy of treating severe flail chest with internal fixation surgery compared with conservative treatments
The objective of the study is to provide evidence for selecting the best treatment approach for severe flail chest by comparing surgical and conservative treatments.
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Open AccessRegulation of T cell function by microRNA-720
Chronic hepatitis B virus (HBV) infection is a major global health burden. Functional exhaustion and numerical reduction of HBV-specific cytotoxic T lymphocytes (CTLs) in the liver and peripheral blood limit a...
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Open AccessChlamydia gallinacea, not C. psittaci, is the endemic chlamydial species in chicken (Gallus gallus)
To investigate the prevalence and diversity of Chlamydia spp. in domestic birds in China, oral and cloacal swabs of healthy chickens, ducks, geese and pigeons were collected nationwide from live-animal markets an...
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Open AccessSOX7 co-regulates Wnt/β-catenin signaling with Axin-2: both expressed at low levels in breast cancer
SOX7 as a tumor suppressor belongs to the SOX F gene subfamily and is associated with a variety of human cancers, including breast cancer, but the mechanisms involved are largely unclear. In the current study,...
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Open AccessPliocene-Quaternary crustal melting in central and northern Tibet and insights into crustal flow
There is considerable controversy over the nature of geophysically recognized low-velocity–high-conductivity zones (LV–HCZs) within the Tibetan crust, and their role in models for the development of the Tibeta...
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Open Access31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
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Erratum to: A metagenomics study for the identification of respiratory viruses in mixed clinical specimens: an application of the iterative map** approach
