58 Result(s)

Article

Computed tomography-guided permanent brachytherapy for locoregional recurrent gastric cancer

Locoregional recurrence is the typical pattern of recurrence in gastric cancer, and cannot be removed by surgery in most of the patients. We aimed to evaluate the feasibility and efficacy of computed tomograph...

Liangrong Shi, Chang** Wu, Jun Wu, Wenjie Zhou, Mei Ji… in Radiation Oncology (2012)

Article

Cytokine-induced killer cells promote antitumor immunity

The number of immune cells, especially dendritic cells and cytotoxic tumor infiltrating lymphocytes (TIL), particularly Th1 cells, CD8 T cells, and NK cells is associated with increased survival of cancer pati...

**gting Jiang, Chang** Wu, Binfeng Lu in Journal of Translational Medicine (2013)

Article

Serum microRNAs profile from genome-wide serves as a fingerprint for diagnosis of acute myocardial infarction and angina pectoris

In order to identify miRNAs expression profiling from genome-wide screen for diagnosis of acute myocardial infarction (AMI) and angina pectoris (AP), we investigated the altered profile of serum microRNAs in A...

Chunjian Li, Zhijuan Fang, Ting Jiang, Qiu Zhang, Chao Liu… in BMC Medical Genomics (2013)

Article

RETRACTED ARTICLE: Up-regulated miR-199a-5p in gastric cancer functions as an oncogene and targets klotho

Recent studies have shown that miR-199a-5p plays opposite roles in cancer initiation and progression of different cancer types, acting as oncogene for some cancer types but as tumor suppressor gene for others....

Xu-Jun He, Ying-Yu Ma, Sheng Yu, **ao-Ting Jiang, Yi-Ding Lu, Liang Tao… in BMC Cancer (2014)

Article

Evaluation of tumor response to cytokine-induced killer cells therapy in malignant solid tumors

CIK cells therapy has been evaluated as an adoptive cell immunotherapy for cancer patients, but there still have not been any standardized systems for evaluating the antitumor efficacy yet. The WHO and RECIST ...

**ao-Dong Li, Mei Ji, **ao Zheng, Zhong-Hua Ning… in Journal of Translational Medicine (2014)

Article

MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells

The mitogen-activated protein kinase kinase/extracellular-signal-regulated kinase (MEK/ERK) signaling pathway is involved in viral life cycle. However, the effect of MEK/ERK pathway in enterovirus 71(EV71)-inf...

Weifeng Shi, Xueling Hou, Hongjun Peng, Li Zhang, Yuanyuan Li… in Virology Journal (2014)

Article

PD-1/PD-L1 pathway in non-small-cell lung cancer and its relation with EGFR mutation

Immunotherapy has become a crucial modality for non-small-cell lung cancer treatment. Recently, two immune checkpoints, PD-1 and PD-L1, have emerged as important targets for immunotherapy. Their antitumor effi...

Mei Ji, Yan Liu, Qing Li, **ao-Dong Li, Wei-Qing Zhao… in Journal of Translational Medicine (2015)

Article

DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

Although the etiology of primary biliary cirrhosis (PBC) remains enigmatic, there are several pieces of data supporting the thesis that a strong genetic predisposition and environmental factors interact to pro...

Ana Lleo, Weici Zhang, Ming Zhao, Yixin Tan, Francesca Bernuzzi… in Clinical Epigenetics (2015)

Article

Lack of association between bovine leukemia virus and breast cancer in Chinese patients

Rong Zhang, **gting Jiang, Weihong Sun, Jilei Zhang, Ke Huang… in Breast Cancer Research (2016)

Article

A prediction model for lymph node metastases using pathologic features in patients intraoperatively diagnosed as stage I non-small cell lung cancer

There is little information on which pattern should be chosen to perform lymph node dissection for stage I non-small-cell lung cancer. This study aimed to develop a model for predicting lymph node metastasis u...

Fei Zhao, Yue Zhou, Peng-Fei Ge, Chen-Jun Huang, Yue Yu, Jun Li, Yun-Gang Sun… in BMC Cancer (2017)

Article

Mosaic UPD(7q)mat in a patient with silver Russell syndrome

Silver-Russell syndrome (SRS) is one of the imprinting disorders characterized by prenatal and postnatal growth restriction, relative macrocephaly, body asymmetry and characteristic facial features. ~ 10% of S...

Jiasun Su, ** Wang, **n Fan, Chunyun Fu, ShuJie Zhang, Yue Zhang… in Molecular Cytogenetics (2017)

Article

MicroRNA-296: a promising target in the pathogenesis of atherosclerosis?

Atherosclerosis has been recognized as an inflammatory disease involving the vascular wall. MicroRNAs are a group of small noncoding RNAs to regulate gene expression at the transcriptional level through mRNA d...

Heng Li, **n-** Ouyang, Ting Jiang, **-Long Zheng, **-** He… in Molecular Medicine (2018)

Article

CTHRC1 induces non-small cell lung cancer (NSCLC) invasion through upregulating MMP-7/MMP-9

The strong invasive and metastatic nature of non-small cell lung cancer (NSCLC) leads to poor prognosis. Collagen triple helix repeat containing 1 (CTHRC1) is involved in cell migration, motility and invasion....

Weiling He, Hui Zhang, Yuefeng Wang, Yanbin Zhou, Yifeng Luo, Yongmei Cui… in BMC Cancer (2018)

Article

Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significance

Recent studies have suggested that B7-H6, a new member of the B7 family of ligands, not only is a crucial regulator of NK cell-mediated immune responses but also has important clinical implications due to its ...

Lujun Chen, Jun Feng, Bin Xu, You Zhou, … in Cancer Cell International (2018)

Article

Correction to: Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significance

Following publication of the original article [1], the authors reported a ty** mistake in the title. In this Correction the incorrect and correct titles are shown.

Lujun Chen, Jun Feng, Bin Xu, You Zhou, … in Cancer Cell International (2018)

Article

Decreased RIG-I expression is associated with poor prognosis and promotes cell invasion in human gastric cancer

Retinoic acid-induced protein I (RIG-I), known as a cytoplastic pattern recognition receptor, can recognize exogenous viral RNAs, and then initiate immune response. Recently, numerous studies also showed that ...

Lujun Chen, Jun Feng, Shaoxian Wu, Bin Xu, You Zhou… in Cancer Cell International (2018)

Article

Neutrophil-to-Lymphocyte Ratio Is an Independent Predictor of 30-Day Mortality of Intracerebral Hemorrhage Patients: a Validation Cohort Study

In a previous study in patients with intracranial hemorrhage (ICH), we found an association between high neutrophil-to-lymphocyte ratio (NLR) with poor short-term mortality. In the current study, this prelimin...

Fei Wang, Li Wang, Ting-ting Jiang, Jian-jun **a, Feng Xu… in Neurotoxicity Research (2018)

Article

Circulating tumor cells with karyoty** as a novel biomarker for diagnosis and treatment of nasopharyngeal carcinoma

Circulating tumor cells (CTCs) have been considered great clinical significance in various cancers. However, it remains unknown that how is the role of CTCs in patients with nasopharyngeal carcinoma (NPC). We ...

**g Zhang, Huashan Shi, Tingting Jiang, Zhe Liu, Peter P. Lin, Nianyong Chen in BMC Cancer (2018)

Article

Three-dimensional nanostructured substrates enable dynamic detection of ALK-rearrangement in circulating tumor cells from treatment-naive patients with stage III/IV lung adenocarcinoma

Circulating tumor cells (CTC) shows great prospect to realize precision medicine in cancer patients.

Weiling He, Di Xu, Zhuo Wang, Hui Wu, **anhong **ang… in Journal of Translational Medicine (2019)

Article

Aberrant fatty acid profile and FFAR4 signaling confer endocrine resistance in breast cancer

Evidence suggests that fatty acid receptor FFAR4 plays a tumor-promoting role in adipose tissue-adjacent malignancies, but its clinical relevance remains unexplored. Here, we investigated the clinical signific...

**ao Chu, Qi Zhou, Yingchun Xu… in Journal of Experimental & Clinical Cancer … (2019)