10,048 Result(s)
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Article
Characteristics and risk factors of axillary lymph node metastasis of microinvasive breast cancer
To select patients who would benefit most from sentinel lymph node biopsy (SLNB) by investigating the characteristics and risk factors of axillary lymph node metastasis (ALNM) in microinvasive breast cancer (M...
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Article
Geometric mean optimizer for achieving efficiency in truss structural design
The objective of this study is to utilize the geometric mean optimizer (GMO) for mass optimization of structural trusses. By harnessing the GMO’s mutation mechanism rooted in a Gaussian framework, the model ef...
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Article
Comparative study on a deactivation kinetic model based on fractional conversion of solid in fluid/solid heterogeneous processes
In this work, the definition of deactivation kinetic model (DKM) has been given under some assumptions and its features were illustrated through comparison with prior kinetic models such as DM (deactivation mo...
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Article
Achieving improved performance in construction projects: advanced time and cost optimization framework
The management of construction projects has long emphasized the delicate balance between time and cost, as these factors play a critical role in achieving optimal project outcomes. To address this challenge, s...
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Article
Open AccessBridging the Gap: Comparing Patient-Clinician Views on Treatment Goals and Communication in the Management of Atopic Dermatitis Within the Asia–Pacific Region
It remains unclear how patients with atopic dermatitis (AD) and clinicians perceive the level of patient–clinician communication and if there could be potential lapses. This cross-sectional study aims to compa...
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Article
Open AccessNilotinib treatment outcomes in autosomal dominant spinocerebellar ataxia over one year
We evaluated the efficacy and safety of 1-year treatment with nilotinib (Tasigna®) in patients with autosomal dominant spinocerebellar ataxia (ADSCA) and the factors associated with responsiveness. From an instit...
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Advancing Cancer Immune Cell Therapies via Engineered iPSC-Based Strategies
Current immunotherapies for cancer treatment face significant challenges, including a low clinical response rate, limited cellular materials for initiation, high costs, and intricate large-scale manufacturing ...
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Article
Modifications of surgical techniques in laparoscopic percutaneous extraperitoneal closure of inguinal ring for childhood inguinal hernia to achieve zero recurrence and zero subcutaneous stitch granuloma
To present our technical modifications of single incision laparoscopic percutaneous extraperitoneal closure (SILPEC) of the internal inguinal ring (IIR) for pediatric inguinal hernia (PIH).
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Effects of dioxin exposure on reproductive and thyroid hormone levels and male sexual function in airbase military workers in Vietnam
Dioxins are endocrine disruptors that may disturb male sexual and reproductive function. Studies on human populations are limited, and their results are controversial. This study evaluated the impact of dioxin...
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Article
Differences in severity of chemotherapy-induced nausea and vomiting between neoadjuvant and adjuvant chemotherapy in patients with breast cancer: analysis of data from two prospective observational studies
We assessed the differences in chemotherapy-induced nausea and vomiting (CINV) severity in patients with breast cancer, receiving neoadjuvant chemotherapy (NAC) and adjuvant chemotherapy (AC).
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Article
Open AccessInter-zonal epithelial thickness differences for early keratoconus detection using optical coherence tomography
To develop and test a parameter for early keratoconus screening by quantifying the localized epithelial thickness differences in keratoconic eyes.
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Article
Open AccessUniversal hydrogel adhesives with robust chain entanglement for bridging soft electronic materials
Ensuring stable integration of diverse soft electronic components for reliable operation under dynamic conditions is crucial. However, integrating soft electronics, comprising various materials like polymers, ...
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Open AccessMultiparametric MRI–based radiomic models for early prediction of response to neoadjuvant systemic therapy in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is often treated with neoadjuvant systemic therapy (NAST). We investigated if radiomic models based on multiparametric Magnetic Resonance Imaging (MRI) obtained early durin...
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Article
Open AccessTwist angle-dependent transport properties of twisted bilayer graphene
Twisted bilayer graphene (tBLG) with small twist angles has attracted significant attention because of its unique electronic properties arising from the formation of a moiré superlattice. In this study, we sys...
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Article
Open AccessClip** the Positive Lymph Node in Patients with Clinically Node Positive Breast Cancer Treated with Neoadjuvant Chemotherapy: Impact on Axillary Surgery in the ISPY-2 Clinical Trial
For patients with clinically node-positive (cN+) breast cancer undergoing neoadjuvant chemotherapy (NAC), retrieving previously clipped, biopsy-proven positive lymph nodes during sentinel lymph node biopsy [i....
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Article
Open AccessA double CYP27A1 gene mutation in spinal cerebrotendinous xanthomatosis in a patient presenting with spastic gait: a case report
Cerebrotendinous xanthomatosis (CTX, OMIM #213700) is a rare inherited metabolic disease caused by the mutation in the CYP27A1 gene. Spinal CTX is a rare clinical subgroup of CTX which lacks typical symptoms seen...
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Article
Simultaneous determination of paracetamol and codeine phosphate in combined tablets by an electrochemical method using TiO2/rGO modified glassy carbon electrode
In the present paper, a nanocomposite of rGO and TiO2 nanoparticles (TiO2/rGO) was prepared by a facile synthesis method with peroxo titanium complexes as TiO2 precursor. The morphology and structure of TiO2/rGO ...
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Article
The quassinoids bruceines A–M: pharmacology, mechanism of action, synthetic advance, and pharmacokinetics—a review
Bruceines A–L are among the quassinoid representatives found in the medicinal plant Brucea javanica (L.). An overview of their pharmacological activities is still unknown. The given research deals with highlights...
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Article
Detection of Fe3+ ions using carbon dots derived from Gac fruit (Momordica cochinchinensis Spreng)
In this paper, a one-step hydrothermal treatment was employed for the synthesis of fluorescent carbon dots (CDs) via Gac fruit. According to the results of the analysis, the average diameter of CDs was 3.5 ± 1...
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Article
Internal Mammary Lymphadenopathy Does Not Impact Oncologic Outcomes in Patients Treated with Neoadjuvant Chemotherapy: Results from the I-SPY2 Clinical Trial
Internal mammary lymphadenopathy (IML) plays a role in breast cancer stage and prognosis. We aimed to evaluate method of IML detection, how IML impacts response to neoadjuvant chemotherapy (NAC), and oncologic...