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9 Result(s)

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  1. Article

    Open Access

    Vascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia

    Vascular smooth muscle cell (VSMC) proliferation is the leading cause of vascular stenosis or restenosis. Therefore, investigating the molecular mechanisms and pivotal regulators of the proliferative VSMC phen...

    Chao Su, Mingxia Liu, Xuyang Yao, Wei Hao… in Cellular and Molecular Life Sciences (2024)

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  2. Article

    Open Access

    A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation

    Multiple tumors are synergistically promoted by c-Met and TRK, and blocking their cross-signalling pathway may give better effects. In this study, we developed a tyrosine kinase inhibitor 1D228, which exhibite...

    Baijiao An, Wenyan Nie, **hui Hu, Yangyang Fan, Haoran Nie… in Cell Death & Disease (2023)

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  3. Article

    Open Access

    Arginase: shedding light on the mechanisms and opportunities in cardiovascular diseases

    Arginase, a binuclear manganese metalloenzyme in the urea, catalyzes the hydrolysis of L-arginine to urea and L-ornithine. Both isoforms, arginase 1 and arginase 2 perform significant roles in the regulation o...

    Zhuozhuo Li, Liwei Wang, Yuanyuan Ren, Yaoyao Huang, Wenxuan Liu… in Cell Death Discovery (2022)

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  4. No Access

    Article

    Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress

    Herein, Tudor-SN was identified as a DNA damage response (DDR)-related protein that plays important roles in the early stage of DDR. X-ray or laser irradiation could evoke the accumulation of Tudor-SN to DNA d...

    **ao Fu, Chunyan Zhang, Hao Meng, Kai Zhang, Lei Shi… in Cell Death & Differentiation (2018)

  5. No Access

    Article

    Calcium regulates glutamate dehydrogenase and poly-γ-glutamic acid synthesis in Bacillus natto

    To study the effect of Ca2+ on glutamate dehydrogenase (GDH) and its role in poly-γ-glutamic acid (γ-PGA) synthesis in Bacillus natto HSF 1410.

    Yonghong Meng, Guiru Dong, Chen Zhang, Yuanyuan Ren, Yuling Qu… in Biotechnology Letters (2016)

  6. No Access

    Article

    Metabolic and phylogenetic analyses based on nitrogen in a new poly-γ-glutamic acid-producing strain of Bacillus subtilis

    Nitrogen metabolism was investigated during poly-γ-glutamic acid (γ-PGA) synthesis and phylogenetic analyses was used to explore glutamate dependency in Bacillus subtilis HSF1410.

    Yuanyuan Ren, Baiqi Huang, Yonghong Meng, Lina Wei, Chen Zhang in Biotechnology Letters (2015)

  7. No Access

    Article

    Differential profiling analysis of miRNAs reveals a regulatory role in low N stress response of Populus

    Nitrogen (N) is an essential mineral element for plant growth processes, and its availability severely affects the productivity of plants, especially trees. MicroRNAs (miRNAs) are a class of non-coding RNAs ap...

    Yuanyuan Ren, Fengshuo Sun, Jia Hou, Lei Chen… in Functional & Integrative Genomics (2015)

  8. No Access

    Article

    Identification of novel and conserved Populus tomentosa microRNA as components of a response to water stress

    MicroRNAs (miRNAs) are a class of small, non-coding RNAs that play important downregulation roles in plants growth, development, and stress responses. To better identify Populus tomentosa miRNAs and understand th...

    Yuanyuan Ren, Lei Chen, Yiyun Zhang, **angyang Kang… in Functional & Integrative Genomics (2012)

  9. No Access

    Article

    Thermostable esterase from Thermoanaerobacter tengcongensis: high-level expression, purification and characterization

    The lipA gene encoding a thermostable esterase was cloned from Thermoanaerobacter tengcongensis and overexpressed in Escherichia coli. The recombinant esterase, with a molecular mass of approx. 43 kDa determined ...

    Jian Zhang, **gfang Liu, Jian Zhou, Yuanyuan Ren, **uyu Dai… in Biotechnology Letters (2003)