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Article
Open AccessGenome-wide identification of WRKY transcription factors in Casuarina equisetifolia and the function analysis of CeqWRKY11 in response to NaCl/NaHCO3 stresses
Casuarina equisetifolia (C. equisetifolia) is a woody species with many excellent features. It has natural resistance against drought, salt and saline-alkali stresses. WRKY transcription factors (TFs) play signif...
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Article
Open AccessStructural characteristics of gut microbiota in longevity from Changshou town, Hubei, China
The gut microbiota (GM) and its potential functions play a crucial role in maintaining host health and longevity. The aim of this study was to investigate the potential relationship between GM and longevity. W...
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Article
Vitamin D inhibits ferroptosis and mitigates the kidney injury of prediabetic mice by activating the Klotho/p53 signaling pathway
Diabetic nephropathy (DN) is a serious public health problem worldwide, and ferroptosis is deeply involved in the pathogenesis of DN. Prediabetes is a critical period in the prevention and control of diabetes ...
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Article
Open AccessIdentification of CXCL16 as a diagnostic biomarker for obesity and intervertebral disc degeneration based on machine learning
Intervertebral disc degeneration (IDD) is the primary cause of neck and back pain. Obesity has been established as a significant risk factor for IDD. The objective of this study was to explore the molecular me...
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Article
Open AccessQTG-Miner aids rapid dissection of the genetic base of tassel branch number in maize
Genetic dissection of agronomic traits is important for crop improvement and global food security. Phenotypic variation of tassel branch number (TBN), a major breeding target, is controlled by many quantitativ...
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Article
Study on Influence of Shallow Buried Tunnel Excavation on Adjacent Bridge Piles
The influence of metro tunnel excavation on the surrounding existing structures should not be ignored. According to the characteristics of the tunnel side passing through the Beiyuan viaduct pile of **an Metr...
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Article
Transcriptomic analysis the mechanisms of anti-osteoporosis of desert-living Cistanche herb in ovariectomized rats of postmenopausal osteoporosis
Desert-living Cistanche herb (DC), as a traditional Chinese medicine for tonifying kidney yang, is often used to treat postmenopausal osteoporosis (PMOP). Total phenylethanoid glycosides are instruction ingred...
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Article
Open AccessA translatome-transcriptome multi-omics gene regulatory network reveals the complicated functional landscape of maize
Maize (Zea mays L.) is one of the most important crops worldwide. Although sophisticated maize gene regulatory networks (GRNs) have been constructed for functional genomics and phenotypic dissection, a multi-omic...
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Article
Open AccessMiRNA-363-3p/DUSP10/JNK axis mediates chemoresistance by enhancing DNA damage repair in diffuse large B-cell lymphoma
Anthracycline-based chemotherapy resistance represents a major challenge in diffuse large B-cell lymphoma (DLBCL). MiRNA and gene expression profiles (n = 47) were determined to uncover potential chemoresistance ...
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Article
Open AccessThe two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context
Activating transcription factor-2 (ATF2) is a member of the basic leucine zipper family of DNA-binding proteins, which exhibits both oncogenic and tumor suppression activity in different tumors. However, the m...
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Article
Open AccessHOXC10 promotes growth and migration of melanoma by regulating Slug to activate the YAP/TAZ signaling pathway
Homeobox C10 (HOXC10) has been reported to participate in various cancers. However, the involvement of HOXC10 in melanoma is still unknown. Here, we attempted to determine whether HOXC10 can affect the develop...
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Article
Open AccessGenome-wide association and transcriptome studies identify candidate genes and pathways for feed conversion ratio in pigs
The feed conversion ratio (FCR) is an important productive trait that greatly affects profits in the pig industry. Elucidating the genetic mechanisms underpinning FCR may promote more efficient improvement of ...
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Chapter and Conference Paper
Markov Chain-Based Statistical Model of Three-State SIMO Land Mobile Satellite Channel
In order to analyze the applicability of single-input multiple-out (SIMO) technology in land mobile satellite system, this paper establishes a three-state SIMO-LMS channel statistical model based on Markov cha...
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Chapter and Conference Paper
Co-channel Interference Between Satellite and 5G System in C Band
The 2019 World Radio Conference proposed to add 11 candidate frequency bands for the 5G system. Some of the C-bands are frequencies currently operated by the fixed-satellite service. When the 5G system and the...
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Chapter and Conference Paper
Interference Analysis Between Satellite and 5G Network
As the development of 5G technology gradually matures, the integration of satellites and 5G cellular networks has gradually become the focus of industry attention. In particular, the current scarcity of spectr...
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Article
Open AccessCharacterization of a novel STAT 2 knock-out hamster model of Crimean-Congo hemorrhagic fever virus pathogenesis
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen causing a febrile illness in humans, which can progress to hemorrhagic manifestations, multi-organ failure, and death. Current mouse model...
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Article
Open AccessReal-time manipulation of intestinal peristalsis by enteric-encapsulated magnetic nanoparticles & wearable 3D-printed devices
The present study introduced a new biomedical engineering concept to realize the real-time adjustment of nutrient absorption. With the aid of a 3D-printed wearable external magnet device, both the location and...
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Protocol
Production of Genetically Engineered Porcine Embryos by Handmade Cloning
Genetic engineering is essential to realize the full potentials of pigs both as livestock and as animal models of human disease. With the development of new genetic engineering technologies, such as the cluste...
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Chapter
Nanotheranostics-Based Imaging for Cancer Treatment Monitoring
The rapidly develo** field of cancer treatment requires versatile strategies for controlled drug delivery and diagnostics. Molecular imaging technology has gained attraction in cancer diagnosis and therapy, ...
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Article
Open AccessProteomic analysis indicates that mitochondrial energy metabolism in skeletal muscle tissue is negatively correlated with feed efficiency in pigs
Feed efficiency (FE) is a highly important economic trait in pig production. Investigating the molecular mechanisms of FE is essential for trait improvement. In this study, the skeletal muscle proteome of high...
