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Article
DKK3 promotes oxidative stress injury and fibrosis in HK-2 cells by activating NOX4 via β-catenin/TCF4 signaling
Oxidative stress and fibrosis may accelerate the progression of chronic kidney disease (CKD). DKK3 is related to regulating renal fibrosis and CKD. However, the molecular mechanism of DKK3 in regulating oxidat...
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Article
Titanium Dioxide Nanoparticles Induce Cell Cycle Arrest and Apoptosis through Inhibiting PI3K/AKT/mTOR Pathway in Spermatogonia
Titanium dioxide nanoparticles (TiO2 NPs) can result in the reduction of sperm numbers, but the mechanisms have not been well elucidated. The purpose of this study was to investigate the effects of TiO2 NPs on ce...
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Article
Moraxella nasibovis sp. nov., Isolated from a Cow with Respiratory Disease
Strain ZY190618T, isolated from the nasal cavity of a cow with respiratory disease, was subjected to taxonomic characterization. Cells of the strain were Gram-stain-negative, aerobic and coccus-shaped. Phylogenet...
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Article
Moraxella nasicaprae sp. nov., Isolated from a Goat with Respiratory Disease
A novel Gram-stain-negative, aerobic, irregular coccus designated as ZY201224T, was isolated from the nasal cavity of a goat with respiratory disease in a goat farm, located at Jianshui, Yunnan Province, PR China...
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Article
Nanosized Titanium Dioxide Induced Apoptosis and Abnormal Expression of Blood-Testis Barrier Junction Proteins Through JNK Signaling Pathway in TM4 Cells
Nanosized titanium dioxide (nano-TiO2) has been widely used in consumer products. It can cross the blood-testis barrier (BTB), and it has adverse effects on the male reproductive system. However, the specific mec...
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Article
Open AccessResponse and Adaptation of Single-Crop** Rice Growth Periods to Sowing Date, Cultivar Shift and Extreme Temperatures in China from 1981 to 2010
Crop growth period responses to climate change directly affect yield and quality; these changes have been investigated, but few studies have researched the quantitative effects of the sowing date (SD), cultiva...
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Article
Lycopene Alleviates Titanium Dioxide Nanoparticle-Induced Testicular Toxicity by Inhibiting Oxidative Stress and Apoptosis in Mice
The research was carried out to investigate the possible ameliorative effect of lycopene on TiO2 NPs-induced male reproductive toxicity and explore the possible mechanism.
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Article
Open AccessTargeted P2X7/NLRP3 signaling pathway against inflammation, apoptosis, and pyroptosis of retinal endothelial cells in diabetic retinopathy
Retinal endothelial cells (RECs) are the primary target cells for diabetes-induced vascular damage. The P2X7/NLRP3 pathway plays an essential role in amplifying inflammation via an ATP feedback loop, promoting...
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Article
Open AccessPhysiological responses and transcriptomic changes reveal the mechanisms underlying adaptation of Stylosanthes guianensis to phosphorus deficiency
Phosphorus (P) is an essential macronutrient for plant growth that participates in a series of biological processes. Thus, P deficiency limits crop growth and yield. Although Stylosanthes guianensis (stylo) is an...
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Article
Effect of Nano-Titanium Dioxide on Blood-Testis Barrier and MAPK Signaling Pathway in Male Mice
Some studies have found that nano-sized titanium dioxide (nano-TiO2) has adverse effects on the male reproductive system. Blood-testis barrier (BTB), as one of the tightest blood-tissue restriction, is crucial to...
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Article
Genotoxicity Evaluation of Titanium Dioxide Nanoparticles In Vitro: a Systematic Review of the Literature and Meta-analysis
With the wide use of titanium dioxide nanoparticles (TiO2-NPs), the genotoxicity of TiO2-NPs, which is a factor for safety assessment, has attracted people’s attention. However, their genotoxic effects in vitro r...
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Article
Open AccessNew approach to calculating tree height at the regional scale
Determining the spatial distribution of tree heights at the regional area scale is significant when performing forest above-ground biomass estimates in forest resource management research. The geometric-optica...
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Article
Seasonal Dynamics of Copper Deficiency in Wumeng Semi-Fine Wool Sheep
A study of the seasonal dynamics of copper (Cu) deficiency and its effects on the antioxidant system in Wumeng semi-fine wool sheep in Weining county was conducted. In addition, the concentrations of mineral e...
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Article
The Variable Regulatory Effect of Arsenic on Nrf2 Signaling Pathway in Mouse: a Systematic Review and Meta-analysis
Arsenic is known to cause oxidative damage. Nuclear factor E2-relate factor-2 (Nrf2) can resist this toxicity. Scholars demonstrated that Nrf2 pathway was activated by arsenic. In contrast, other articles esta...
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Article
Alleviation of Arsenic-Induced Pulmonary Oxidative Damage by GSPE as Shown during In vivo and In vitro Experiments
A long-term exposure to arsenic may lead to lung damage due to oxidative stress. In this context, GSPE can play a major role as a strong antioxidant. Our study attempted to reveal the connection between arseni...
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Article
Characterization of a protocatechuate catabolic gene cluster in Rhodococcus ruber OA1 involved in naphthalene degradation
In this study, we investigated a protocatechuate catabolic gene cluster involved in naphthalene degradation in Rhodococcus ruber OA1. Rhodococcus ruber OA1 was isolated from the pharmaceutical wastewater treatmen...
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Article
Effects of rosiglitazone on proliferation and differentiation of duck preadipocytes
Rosiglitazone (RSG), one member of the thiazolidinediones (TZDs), is a type of anti-diabetic drug in diabetic humans and animal models, whose function remains unknown in waterfowl. In this study, effects of RS...
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Article
Open AccessEffects of CuO nanoparticles on Lemna minor
Copper dioxide nanoparticles (NPs), which is a kind of important and widely used metal oxide NP, eventually reaches a water body through wastewater and urban runoff. Ecotoxicological studies of this kind of NP...
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Open AccessCrystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14
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Fauna characteristics and ecological distribution of Carnivora and Artiodactyla in Niubeiliang National Nature Reserve, China
Niubeiliang National Nature Reserve (NNR, 108°45′–109°04′E, 33°47′–33°56′N) is located on the eastern range of the Qinling Mountains in Shaanxi Province, China and spans the southern and northern slopes of Mt....