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Article
Di-caffeoylquinic acid: a potential inhibitor for amyloid-beta aggregation
Alzheimer's disease (AD) remains a challenging neurodegenerative disorder with limited therapeutic success. Traditional Chinese Medicine (TCM), as a promising new source for AD, still requires further explorat...
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Article
Open AccessObservation of structural and vascular features of retina and choroid in myopia using ultra-widefield SS-OCTA
To find the relationship between the changes of retinal and choriodal structure/ vascular densities (VD) and the myopia progress.
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Article
DKK3 promotes oxidative stress injury and fibrosis in HK-2 cells by activating NOX4 via β-catenin/TCF4 signaling
Oxidative stress and fibrosis may accelerate the progression of chronic kidney disease (CKD). DKK3 is related to regulating renal fibrosis and CKD. However, the molecular mechanism of DKK3 in regulating oxidat...
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Article
Wnt/β-catenin Pathway Aggravates Renal Fibrosis by Activating PUM2 Transcription to Repress YME1L-mediated Mitochondrial Homeostasis
Chronic kidney disease (CKD) affects more than 10% of people worldwide and is a leading cause of death. However, the pathogenesis of CKD remains elusive. The oxidative stress and mitochondrial membrane potenti...
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Article
Tumor and metastatic lymph nodes metabolic activity on 18F-FDG-PET/CT to predict progression-free survival in locally advanced cervical cancer
The present study investigated the predictive diseases progression value of preoperative fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in patients with local advanced cervi...
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Article
Wet activation and electrochemical performance of the residual carbon from coal gasification fine slag
With the rapid development of coal chemical industries, the production of solid waste gasification slag is increasing year by year. How to efficiently utilize gasification slag has become an urgent problem to ...
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Chapter and Conference Paper
Design and Verification of Variable Camber Wing Based on Cellular Structure
Cellular structure is an ideal way to realize adaptive flexible deformation of wings due to its lightweight, high stiffness, high building speed and reusable characteristics. On the one hand, the cellular stru...
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Chapter and Conference Paper
Flexible Sensor Array and Newton Interpolation Algorithm for Molded Dichromatic Sole by Operating Robot
Based on the principle of system engineering and optimization method, the multi-color soles mold operation robot was constructed instead of manual operation, and the double-layer quality inspection standard of...
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Article
A method for predicting water quality of river basin based on OVMD-GAT-GRU
Water pollution has serious consequences for human health and water ecosystems, and accurate forecasting of water quality changes can aid in the early detection and treatment of such pollution. To better simul...
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Article
Open AccessAnti-VEGFR2 F(ab′)2 drug conjugate promotes renal accumulation and glomerular repair in diabetic nephropathy
Poor renal distribution of antibody-based drugs is the key factor contributing to low treatment efficiency for renal diseases and side effects. Here, we prepare F(ab′)2 fragmented vascular endothelial growth fact...
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Article
Titanium Dioxide Nanoparticles Induce Cell Cycle Arrest and Apoptosis through Inhibiting PI3K/AKT/mTOR Pathway in Spermatogonia
Titanium dioxide nanoparticles (TiO2 NPs) can result in the reduction of sperm numbers, but the mechanisms have not been well elucidated. The purpose of this study was to investigate the effects of TiO2 NPs on ce...
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Article
Open AccessLipIDens: simulation assisted interpretation of lipid densities in cryo-EM structures of membrane proteins
Cryo-electron microscopy (cryo-EM) enables the determination of membrane protein structures in native-like environments. Characterising how membrane proteins interact with the surrounding membrane lipid enviro...
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Article
Open AccessCapturing nascent extracellular vesicles by metabolic glycan labeling-assisted microfluidics
Extracellular vesicle (EV) secretion is a dynamic process crucial to cellular communication. Temporally sorting EVs, i.e., separating the newly-produced ones from the pre-existing, can allow not only deep unde...
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Article
Microstructure and Mechanical Property of Copper–Steel Dissimilar Friction Stir Weld Fabricated by Presetting an Integrated Aluminum Barrier Layer
The conventional friction stir welding (FSW) of dissimilar materials with high melting points, such as copper and steel, is prone to involve harmful intermetallic compounds (IMCs), large welding forces and the...
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Article
Open AccessAssociation of nocturia of self-report with estimated glomerular filtration rate: a cross-sectional study from the NHANES 2005–2018
Nocturia is a manifestation of systemic diseases, in which chronic kidney disease (CKD) is an independent predictor of nocturia due to its osmotic diuretic mechanism. However, to our knowledge, previous studie...
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Article
Moraxella nasibovis sp. nov., Isolated from a Cow with Respiratory Disease
Strain ZY190618T, isolated from the nasal cavity of a cow with respiratory disease, was subjected to taxonomic characterization. Cells of the strain were Gram-stain-negative, aerobic and coccus-shaped. Phylogenet...
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Article
Dual Interface Synergistic Catalysis: The Selective Hydrogenation of Crotonaldehyde Over Pt/Co3O4@PDA
Selective hydrogenation of crotonaldehyde to crotyl alcohol over PDA (polydopamine) modified Co3O4 supported Pt catalysts was investigated in liquid phase. The catalysts which contain PDA and Co3O4 lead to the fo...
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Article
An integrated evaluation of climatic suitability for summer peanut at county level by coupling drought-waterlogging risk with potential productivity: a case study in Henan province, China
Develo** a reasonable crop planting layout under climate change is critical for improving peanut yield and alleviating the contradiction of edible oil in China. Henan province is strengthening summer peanut ...
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Article
Moraxella nasicaprae sp. nov., Isolated from a Goat with Respiratory Disease
A novel Gram-stain-negative, aerobic, irregular coccus designated as ZY201224T, was isolated from the nasal cavity of a goat with respiratory disease in a goat farm, located at Jianshui, Yunnan Province, PR China...
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Article
The suitability for potato production in the north single crop** region in China: an integrated evaluation based on yield variability
China is strengthening potato production and cultivation. Develo** a reasonable potato planting layout under climate change is critical for making decisions to sustainably improve potato yield. Here we evalu...
