3 Result(s)

Article

Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease

Interleukin 27 (IL-27), a heterodimeric cytokine composed of Epstein-Barr virus-induced 3 and p28, is a pleiotropic cytokine with both pro-and anti-inflammatory properties. However, the precise role of IL-27 i...

Huanle Gong, Shoubao Ma, Jia Chen, Bingyu Yang… in Signal Transduction and Targeted Therapy (2022)

Article

IL-39 promotes chronic graft-versus-host disease by increasing T and B Cell pathogenicity

Chronic graft-versus-host disease (cGVHD) remains a major complication during the late phase of allogeneic hematopoietic stem cell transplantation (allo-HSCT). IL-39, a newly described pro-inflammatory cytokin...

Kangkang Lv, Bo Hu, Mingzhu Xu, Li Wan, Ziqi **… in Experimental Hematology & Oncology (2022)

Article

High stearic acid diet modulates gut microbiota and aggravates acute graft-versus-host disease

Bingyu Yang, **anfeng Zhang, Huanle Gong… in Signal Transduction and Targeted Therapy (2021)