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Article
Comparative efficacies of two fungal insecticides in field control of cereal aphids heavily infesting winter wheat
Sustainable control of cereal aphids during late spring and early summer requires alternatives to mitigate increasing resistance to chemical insecticides. Emulsifiable oil-formulated Beauveria bassiana ZJU435 (Bb...
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Article
Open AccessSilicon photocathode functionalized with osmium complex catalyst for selective catalytic conversion of CO2 to methane
Solar-driven CO2 reduction to yield high-value chemicals presents an appealing avenue for combating climate change, yet achieving selective production of specific products remains a significant challenge. We show...
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Article
Mass spectrometry-based proteomic landscape of rice reveals a post-transcriptional regulatory role of N6-methyladenosine
Rice is one of the most important staple food and model species in plant biology, yet its quantitative proteomes are largely uncharacterized. Here we quantify the relative protein levels of over 15,000 genes a...
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Article
Enantioselective alkyl–alkyl coupling by Ni-catalysed asymmetric cross-hydrodimerization of alkenes
Saturated tertiary stereogenic carbon centres are common in small molecules and organic materials. Transition-metal-catalysed asymmetric alkyl–alkyl bond formation processes represent contemporary techniques f...
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Article
Open AccessCorrection: ABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies
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Article
Open AccessHealth and wellbeing of staff working at higher education institutions globally during the post-COVID-19 pandemic period: evidence from a cross-sectional study
The ongoing global crisis of Higher Education (HE) institutions during the post-COVID-19 pandemic period has increased the likelihood of enduring psychological stressors for staff. This study aimed to identify...
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Article
Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics
The Internet Data Center (IDC) is one of the most important infrastructures in the field of information technology. The cooling system for heat dissipation of IDC is indispensable due to it generates a large a...
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Article
Enhancement of dissolution and oral bioavailability by adjusting microenvironment pH in crocetin ternary solid dispersions: Optimization, characterization, in vitro evaluation, and pharmacokinetics
The most promising active ingredient of Crocus sativus L., crocetin (CCT), has been demonstrated to possess many biological activities. However, only a few studies have been conducted on CCT formulation, especial...
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Article
Open AccessHER2-targeting antibody drug conjugate FS-1502 in HER2-expressing metastatic breast cancer: a phase 1a/1b trial
Currently approved HER2-targeting antibody-drug conjugates (ADCs) for HER2-positive breast cancer (BC) are associated with safety concerns. In this multicenter, single-arm, dose-escalation (phase 1a) and dose-...
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Article
Open AccessProstaglandin I2 signaling prevents angiotensin II-induced atrial remodeling and vulnerability to atrial fibrillation in mice
Atrial fibrillation (AF) is the most common arrhythmia, and atrial fibrosis is a pathological hallmark of structural remodeling in AF. Prostaglandin I2 (PGI2) can prevent the process of fibrosis in various tissue...
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Article
Vitamin consumption and the ontogenesis of cathepsins and antioxidant capacity in develo** embryos of turbot, Scophthalmus maximus
During embryonic development, vitamins are involved in energy metabolism and protein synthesis, while cathepsins and antioxidant defense play key roles in yolk degradation and protecting fish embryos from oxid...
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Article
Correction: Nomogram based on pretreatment hepatic and renal function indicators for survival prediction of locally advanced esophageal squamous cell carcinoma with treatment of neoadjuvant chemoradiotherapy plus surgery
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Article
Discovery of a novel BTK inhibitor S-016 and identification of a new strategy for the treatment of lymphomas including BTK inhibitor-resistant lymphomas
Bruton’s tyrosine kinase (BTK) has emerged as a therapeutic target for B-cell malignancies, which is substantiated by the efficacy of various irreversible or reversible BTK inhibitors. However, on-target BTK m...
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Article
Open AccessThe clinical practice and dosimetric outcome of the manual adaptive planning during definitive radiotherapy for cervical cancer
To evaluate the advantage of the manual adaptive plans comparing to the scheduled plans, and explored clinical factors predicting patients suitable for adaptive strategy.
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Article
Recent progress and strategies of cathodes toward polysulfides shuttle restriction for lithium-sulfur batteries
Lithium-sulfur batteries (LSBs) have already developed into one of the most promising new-generation high-energy density electrochemical energy storage systems with outstanding features including high-energy d...
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Article
Open AccessABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies
Numerous studies have been conducted to investigate the relationship between ABO and Rhesus (Rh) blood groups and various health outcomes. However, a comprehensive evaluation of the robustness of these associa...
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Article
Open AccessRetinoic acid mitigates the NSC319726-induced spermatogenesis dysfunction through cuproptosis-independent mechanisms
Copper ionophore NSC319726 has attracted researchers' attention in treating diseases, particularly cancers. However, its potential effects on male reproduction during medication are unclear. This study aimed t...
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Article
Microneedle assisted delivery of epidermal and dermal stem cells to promote hair growth
Advances in effective treatment options for hair loss hold paramount importance for individuals on both psychological and physical levels. Cell-based therapies for hair loss hold great promise due to their pot...
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Article
Recent Frontiers in Anisotropic Wet Chemical Etching Techniques for Precision Surface Modification of Industrial-Grade Bulk Crystalline Silicon Wafers: Enhancing Performance in Photovoltaics and MEMS Devices
Surface treatment is a pivotal technique for enhancing the properties of industrial-grade bulk c-silicon wafers, revolutionizing their applicability in both PV and MEMS applications. In this paper we presents ...
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Article
Open AccessANKFY1 bridges ATG2A-mediated lipid transfer from endosomes to phagophores
Macroautophagy is a process that cells engulf cytosolic materials by autophagosomes and deliver them to lysosomes for degradation. The biogenesis of autophagosomes requires ATG2 as a lipid transfer protein to ...
