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Open AccessPolar Bloch points in strained ferroelectric films
Topological domain structures have drawn great attention as they have potential applications in future electronic devices. As an important concept linking the quantum and classical magnetism, a magnetic Bloch ...
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Open AccessCrack mechanism and experimental verification on straightening of AZ31B magnesium alloy plate
When plates with edge cracks in the rolling process is straightened by cyclic tensile and compressive stress, the tip of edge crack always accompanied by stress concentration, which leads to crack propagation....
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Open AccessAuthor Correction: Global patterns of climate change impacts on desert bird communities
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Open AccessGlobal patterns of climate change impacts on desert bird communities
The world’s warm deserts are predicted to experience disproportionately large temperature increases due to climate change, yet the impacts on global desert biodiversity remain poorly understood. Because specie...
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Open AccessCollateral sensitivity to pleuromutilins in vancomycin-resistant Enterococcus faecium
The acquisition of resistance to one antibiotic sometimes leads to collateral sensitivity to a second antibiotic. Here, we show that vancomycin resistance in Enterococcus faecium is associated with a remarkable i...
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Open AccessTopological charge-entropy scaling in kagome Chern magnet TbMn6Sn6
In ordinary materials, electrons conduct both electricity and heat, where their charge-entropy relations observe the Mott formula and the Wiedemann-Franz law. In topological quantum materials, the transverse m...
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Layer Hall effect in a 2D topological axion antiferromagnet
Whereas ferromagnets have been known and used for millennia, antiferromagnets were only discovered in the 1930s1. At large scale, because of the absence of global magnetization, antiferromagnets may seem to behav...
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Open AccessPRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome
The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27 di-methylation (H3K27me2) and H3K27 tri-methylation (H3K27...
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Open AccessThe Prognostic Value of Deficient Mismatch Repair in Stage II–IVa Nasopharyngeal Carcinoma in the Era of IMRT
In the era of intensity-modulated radiotherapy (IMRT), it is important to analyse the prognostic value of deficient mismatch repair (dMMR) in nasopharyngeal carcinoma (NPC). In this study, in pretreatment biop...
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Open AccessPolymorphic cobalt diselenide as extremely stable electrocatalyst in acidic media via a phase-mixing strategy
Many platinum group metal-free inorganic catalysts have demonstrated high intrinsic activity for diverse important electrode reactions, but their practical use often suffers from undesirable structural degrada...
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Open AccessBerberine inhibits adipocyte differentiation, proliferation and adiposity through down-regulating galectin-3
This study is designed to investigate the effects of berberine (BBR) on galectin-3 (Gal-3) and the relationships to its suppressive activities on adipocyte differentiation, proliferation and adiposity. Our res...
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Open AccessIdentification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan
Early detection and accurate monitoring of chronic kidney disease (CKD) could improve care and retard progression to end-stage renal disease. Here, using untargeted metabolomics in 2155 participants including ...
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Open AccessAlterations of Sphingolipid Metabolism in Different Types of Polycystic Ovary Syndrome
The roles of sphingolipids in polycystic ovary syndrome (PCOS) are still unknown. This study aimed to investigate the sphingolipid characteristics for different types of PCOS using liquid chromatography-mass s...
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Observation of the nonlinear Hall effect under time-reversal-symmetric conditions
The electrical Hall effect is the production, upon the application of an electric field, of a transverse voltage under an out-of-plane magnetic field. Studies of the Hall effect have led to important breakthro...
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Open AccessRing synthetic chromosome V SCRaMbLE
Structural variations (SVs) exert important functional impacts on biological phenotypic diversity. Here we show a ring synthetic yeast chromosome V (ring_synV) can be used to continuously generate complex geno...
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Open AccessComparative metabolomics study on therapeutic mechanism of electro-acupuncture and moxibustion on rats with chronic atrophic gastritis (CAG)
Some studies have proved that both acupuncture and moxibustion are very effective for the treatment of CAG. However, little is known about therapeutic mechanism of electro-acupuncture and moxibustion on CAG as...
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Open AccessClinicopathological and molecular characteristics of synchronous gastric adenocarcinoma and gastrointestinal stromal tumors
Synchronous gastric tumors that consist of both gastrointestinal stromal tumor (GIST) and adenocarcinoma are rare. We studied the clinicopathological and molecular characteristics of six cases containing both ...
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Open AccessDecision-making in primary onset middle-age type 2 diabetes mellitus: a BOLD-fMRI study
Although type 2 diabetes mellitus (T2DM) is a well-recognized risk factor for dementia, the neural mechanisms that underlying cognitive impairment in T2DM remain unclear. We used functional magnetic resonance ...
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Open AccessHarvesting more grain zinc of wheat for human health
Increasing grain zinc (Zn) concentration of cereals for minimizing Zn malnutrition in two billion people represents an important global humanitarian challenge. Grain Zn in field-grown wheat at the global scale...
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Open AccessActivated hepatic stellate cells secrete periostin to induce stem cell-like phenotype of residual hepatocellular carcinoma cells after heat treatment
Some evidences show that residual tumor after thermal ablation will progress rapidly. However, its mechanisms remain unclear. Here, we assessed whether activated HSCs could regulate stem cell-like property of ...