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Open AccessCholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell lymphoma (DLBCL). However, its efficacy in treating primary ref...
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Open AccessDGPRI, a new liver fibrosis assessment index, predicts recurrence of AFP-negative hepatocellular carcinoma after hepatic resection: a single-center retrospective study
Although patients with alpha-fetoprotein-negative hepatocellular carcinoma (AFPNHCC) have a favorable prognosis, a high risk of postoperative recurrence remains. We developed and validated a novel liver fibros...
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Open AccessThe effects of probiotics supplementation on Helicobacter pylori standard treatment: an umbrella review of systematic reviews with meta-analyses
Helicobacter pylori infection, a worldwide health issue, is typically treated with standard antibiotic therapies. However, these treatments often face resistance and non-compliance due to side effects. In this um...
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Open AccessStrong linkage between benthic oxygen uptake and bacterial tetraether lipids in deep-sea trench regions
Oxygen in marine sediments regulates many key biogeochemical processes, playing a crucial role in sha** Earth’s climate and benthic ecosystems. In this context, branched glycerol dialkyl glycerol tetraethers...
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Open AccessLipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis
Oxidative stress-induced lipid accumulation is mediated by lipid droplets (LDs) homeostasis, which sequester vulnerable unsaturated triglycerides into LDs to prevent further peroxidation. Here we identify the ...
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Open AccessLow thermal contact resistance boron nitride nanosheets composites enabled by interfacial arc-like phonon bridge
Two-dimensional materials with ultrahigh in-plane thermal conductivity are ideal for heat spreader applications but cause significant thermal contact resistance in complex interfaces, limiting their use as the...
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Open AccessPredicting nodal influence via local iterative metrics
Nodal spreading influence is the capability of a node to activate the rest of the network when it is the seed of spreading. Combining nodal properties (centrality metrics) derived from local and global topolog...
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Open AccessNumerical simulation of autoclaved aerated concrete masonry wall subjected to close-in explosion and the structural damage assessment
In this study, we investigated the destructive effect of autoclaved aerated concrete (AAC) masonry walls subjected to close-in explosions. First, full-size refined finite-element models of the AAC masonry wall...
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Open AccessGround-state electron transfer in all-polymer donor:acceptor blends enables aqueous processing of water-insoluble conjugated polymers
Water-based conductive inks are vital for the sustainable manufacturing and widespread adoption of organic electronic devices. Traditional methods to produce waterborne conductive polymers involve modifying th...
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Open AccessPublisher Correction: Size-fractionated microbiome observed during an eight-month long sampling in Jiaozhou Bay and the Yellow Sea
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Open AccessSize-fractionated microbiome observed during an eight-month long sampling in Jiaozhou Bay and the Yellow Sea
Jiaozhou Bay is a typical semi-enclosed bay with a temperate climate imposed by strong anthropogenic influence. To investigate microbial biodiversity and ecosystem services in this highly dynamic coastal envir...
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Open AccessAn ultrasound-induced wireless power supply based on AlN piezoelectric micromachined ultrasonic transducers
Wireless power transfer is one of the enabling technologies for powering implantable biomedical devices. Biocompatibility and CMOS compatibility of wireless power transfer devices are highly desired due to saf...
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Open AccessDeep learning to diagnose Hashimoto’s thyroiditis from sonographic images
Hashimoto’s thyroiditis (HT) is the main cause of hypothyroidism. We develop a deep learning model called HTNet for diagnosis of HT by training on 106,513 thyroid ultrasound images from 17,934 patients and tes...
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Open AccessMap** the energy level alignment at donor/acceptor interfaces in non-fullerene organic solar cells
Energy level alignment (ELA) at donor (D) -acceptor (A) heterojunctions is essential for understanding the charge generation and recombination process in organic photovoltaic devices. However, the ELA at the D...
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Open AccessAuthor Correction: Anatomically revealed morphological patterns of pyramidal neurons in layer 5 of the motor cortex
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Open AccessA holistic genome dataset of bacteria, archaea and viruses of the Pearl River estuary
Estuaries are one of the most important coastal ecosystems. While microbiomes and viromes have been separately investigated in some estuaries, few studies holistically deciphered the genomes and connections of...
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Open AccessAuthor Correction: Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessTargeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19
Research exploring the development and outcome of COVID-19 infections has led to the need to find better diagnostic and prognostic biomarkers. This cross-sectional study used targeted metabolomics to identify ...
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Open AccessProteome and transcriptome analyses of wheat near isogenic lines identifies key proteins and genes of wheat bread quality
The regulation of wheat protein quality is a highly complex biological process involving multiple metabolic pathways. To reveal new insights into the regulatory pathways of wheat glutenin synthesis, we used th...
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Open AccessHMGR overexpression and interference affect the expression of steroidogenic genes and cholesterol content in bovine intramuscular adipocytes
Previously, we found that mevalonic acid stimulates 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGR) expression in bovine intramuscular adipocytes to influence adipocyte differentiation. However, any di...