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  1. Article

    Open Access

    Cholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma

    Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell lymphoma (DLBCL). However, its efficacy in treating primary ref...

    Zi-Xun Yan, Yan Dong, Niu Qiao, Yi-Lun Zhang, Wen Wu, Yue Zhu in Nature Communications (2024)

  2. Article

    Open Access

    DGPRI, a new liver fibrosis assessment index, predicts recurrence of AFP-negative hepatocellular carcinoma after hepatic resection: a single-center retrospective study

    Although patients with alpha-fetoprotein-negative hepatocellular carcinoma (AFPNHCC) have a favorable prognosis, a high risk of postoperative recurrence remains. We developed and validated a novel liver fibros...

    Bolun Zhang, Junshuai Xue, Bowen Xu, Jian** Chang, **n Li in Scientific Reports (2024)

  3. Article

    Open Access

    The effects of probiotics supplementation on Helicobacter pylori standard treatment: an umbrella review of systematic reviews with meta-analyses

    Helicobacter pylori infection, a worldwide health issue, is typically treated with standard antibiotic therapies. However, these treatments often face resistance and non-compliance due to side effects. In this um...

    Zihan Yang, Yueyang Zhou, Ziying Han, Kun He, Yuelun Zhang, Dong Wu in Scientific Reports (2024)

  4. Article

    Open Access

    Strong linkage between benthic oxygen uptake and bacterial tetraether lipids in deep-sea trench regions

    Oxygen in marine sediments regulates many key biogeochemical processes, playing a crucial role in sha** Earth’s climate and benthic ecosystems. In this context, branched glycerol dialkyl glycerol tetraethers...

    Wenjie **ao, Yun** Xu, Donald E. Canfield, Frank Wenzhöfer in Nature Communications (2024)

  5. Article

    Open Access

    Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis

    Oxidative stress-induced lipid accumulation is mediated by lipid droplets (LDs) homeostasis, which sequester vulnerable unsaturated triglycerides into LDs to prevent further peroxidation. Here we identify the ...

    Qilun Zhang, Xuting Shen, **n Yuan, **g Huang, Yaling Zhu in Nature Communications (2024)

  6. Article

    Open Access

    Low thermal contact resistance boron nitride nanosheets composites enabled by interfacial arc-like phonon bridge

    Two-dimensional materials with ultrahigh in-plane thermal conductivity are ideal for heat spreader applications but cause significant thermal contact resistance in complex interfaces, limiting their use as the...

    Ke Zhan, Yucong Chen, Zhiyuan **ong, Yulun Zhang, Siyuan Ding in Nature Communications (2024)

  7. Article

    Open Access

    Predicting nodal influence via local iterative metrics

    Nodal spreading influence is the capability of a node to activate the rest of the network when it is the seed of spreading. Combining nodal properties (centrality metrics) derived from local and global topolog...

    Shilun Zhang, Alan Hanjalic, Huijuan Wang in Scientific Reports (2024)

  8. Article

    Open Access

    Numerical simulation of autoclaved aerated concrete masonry wall subjected to close-in explosion and the structural damage assessment

    In this study, we investigated the destructive effect of autoclaved aerated concrete (AAC) masonry walls subjected to close-in explosions. First, full-size refined finite-element models of the AAC masonry wall...

    Sheng Liu, **angyun Xu, Yilun Zhang, Bukui Zhou, Kezhi Yang in Scientific Reports (2024)

  9. Article

    Open Access

    Ground-state electron transfer in all-polymer donor:acceptor blends enables aqueous processing of water-insoluble conjugated polymers

    Water-based conductive inks are vital for the sustainable manufacturing and widespread adoption of organic electronic devices. Traditional methods to produce waterborne conductive polymers involve modifying th...

    Tiefeng Liu, Johanna Heimonen, Qilun Zhang, Chi-Yuan Yang in Nature Communications (2023)

  10. Article

    Open Access

    Publisher Correction: Size-fractionated microbiome observed during an eight-month long sampling in Jiaozhou Bay and the Yellow Sea

    Jianchang Tao, Wenxiu Wang, JL Weissman, Yongyu Zhang, Songze Chen in Scientific Data (2022)

  11. Article

    Open Access

    Size-fractionated microbiome observed during an eight-month long sampling in Jiaozhou Bay and the Yellow Sea

    Jiaozhou Bay is a typical semi-enclosed bay with a temperate climate imposed by strong anthropogenic influence. To investigate microbial biodiversity and ecosystem services in this highly dynamic coastal envir...

    Jianchang Tao, Wenxiu Wang, JL Weissman, Yongyu Zhang, Songze Chen in Scientific Data (2022)

  12. Article

    Open Access

    An ultrasound-induced wireless power supply based on AlN piezoelectric micromachined ultrasonic transducers

    Wireless power transfer is one of the enabling technologies for powering implantable biomedical devices. Biocompatibility and CMOS compatibility of wireless power transfer devices are highly desired due to saf...

    Zhicong Rong, Menglun Zhang, Yuan Ning, Wei Pang in Scientific Reports (2022)

  13. Article

    Open Access

    Deep learning to diagnose Hashimoto’s thyroiditis from sonographic images

    Hashimoto’s thyroiditis (HT) is the main cause of hypothyroidism. We develop a deep learning model called HTNet for diagnosis of HT by training on 106,513 thyroid ultrasound images from 17,934 patients and tes...

    Qiang Zhang, Sheng Zhang, Yi Pan, Lin Sun, Jianxin Li, Yu Qiao in Nature Communications (2022)

  14. Article

    Open Access

    Map** the energy level alignment at donor/acceptor interfaces in non-fullerene organic solar cells

    Energy level alignment (ELA) at donor (D) -acceptor (A) heterojunctions is essential for understanding the charge generation and recombination process in organic photovoltaic devices. However, the ELA at the D...

    **an’e Li, Qilun Zhang, Jianwei Yu, Ye Xu, Rui Zhang in Nature Communications (2022)

  15. Article

    Open Access

    Author Correction: Anatomically revealed morphological patterns of pyramidal neurons in layer 5 of the motor cortex

    Siqi Jiang, Yue Guan, Shangbin Chen, Xueyan Jia, Hong Ni, Yalun Zhang in Scientific Reports (2022)

  16. Article

    Open Access

    A holistic genome dataset of bacteria, archaea and viruses of the Pearl River estuary

    Estuaries are one of the most important coastal ecosystems. While microbiomes and viromes have been separately investigated in some estuaries, few studies holistically deciphered the genomes and connections of...

    Bu Xu, Fuyan Li, Lanlan Cai, Rui Zhang, Lu Fan, Chuanlun Zhang in Scientific Data (2022)

  17. Article

    Open Access

    Author Correction: Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Yamilé López-Hernández, Joel Monárrez-Espino in Scientific Reports (2022)

  18. Article

    Open Access

    Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19

    Research exploring the development and outcome of COVID-19 infections has led to the need to find better diagnostic and prognostic biomarkers. This cross-sectional study used targeted metabolomics to identify ...

    Yamilé López-Hernández, Joel Monárrez-Espino in Scientific Reports (2021)

  19. Article

    Open Access

    Proteome and transcriptome analyses of wheat near isogenic lines identifies key proteins and genes of wheat bread quality

    The regulation of wheat protein quality is a highly complex biological process involving multiple metabolic pathways. To reveal new insights into the regulatory pathways of wheat glutenin synthesis, we used th...

    Liangjie Lv, Aiju Zhao, Yelun Zhang, Hui Li, **yong Chen in Scientific Reports (2021)

  20. Article

    Open Access

    HMGR overexpression and interference affect the expression of steroidogenic genes and cholesterol content in bovine intramuscular adipocytes

    Previously, we found that mevalonic acid stimulates 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGR) expression in bovine intramuscular adipocytes to influence adipocyte differentiation. However, any di...

    Haichao Lin, Chen Wei, **anglun Zhang, Wei You, Qing **, **uwen Tan in Scientific Reports (2020)

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