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Chapter and Conference Paper
The Intellectual Structure of Business Analytics: 2002–2019
This paper identifies the intellectual structure of business analytics using document co-citation analysis and author co-citation analysis. A total of 333 research documents and 17,917 references from the Web ...
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Article
Pten loss results in inappropriate excitatory connectivity
Pten mutations are associated with autism spectrum disorder. Pten loss of function in neurons increases excitatory synaptic connectivity, contributing to an imbalance between excitation and inhibition. We aime...
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Article
Open AccessSetd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice
SETD5, a gene linked to intellectual disability (ID) and autism spectrum disorder (ASD), is a member of the SET-domain family and encodes a putative histone methyltransferase (HMT). To date, the mechanism by whic...
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Chapter and Conference Paper
Discovering Platform Government Research Trends Using Topic Modeling
Platform government is a key trend in the 4th industrial revolution. This paper presents an empirical analysis of 5810 articles in the Science Direct Database yielded by a search for the keyword ‘platform govern...
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Chapter and Conference Paper
Anatomy Builder VR: Applying a Constructive Learning Method in the Virtual Reality Canine Skeletal System
We present Anatomy Builder VR that examines how a virtual reality (VR) system can support embodied learning in anatomy education. The backbone of the project is to pursue an alternative constructivist pedagogi...
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Article
Open AccessGrowth Associated Protein 43 (GAP-43) as a Novel Target for the Diagnosis, Treatment and Prevention of Epileptogenesis
We previously showed increased growth associated protein 43 (GAP-43) expression in brain samples resected from patients with cortical dysplasia (CD), which was correlated with duration of epilepsy. Here, we us...
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Article
Open AccessRegional-specific effect of fluoxetine on rapidly dividing progenitors along the dorsoventral axis of the hippocampus
Hippocampus-dependent cognitive and emotional function appears to be regionally dissociated along the dorsoventral (DV) axis of the hippocampus. Recent observations that adult hippocampal neurogenesis plays a ...
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Article
Open AccessThe effect of service innovation on R&D activities and government support systems: the moderating role of government support systems in Korea
This study analyzes the effects of R&D activities and government support programs for the product innovation of service industry. With the advent of the knowledge based society, the technology innovation of th...
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Article
Monosynaptic inputs to new neurons in the dentate gyrus
Adult hippocampal neurogenesis is considered important for cognition. The integration of newborn dentate gyrus granule cells into the existing network is regulated by afferent neuronal activity of unspecified ...
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Article
Open AccessA survey of putative secreted and transmembrane proteins encoded in the C. elegans genome
Almost half of the Caenorhabditis elegans genome encodes proteins with either a signal peptide or a transmembrane domain. Therefore a substantial fraction of the proteins are localized to membranes, reside in the...
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Article
BRCA1 tumour suppression occurs via heterochromatin-mediated silencing
Mutations in the tumour suppressor gene BRCA1 lead to breast and/or ovarian cancer. Here we show that loss of Brca1 in mice results in transcriptional de-repression of the tandemly repeated satellite DNA. Brca1 d...
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Article
Erratum to: Induction of G1/S Phase Arrest and Apoptosis by Quercetin in Human Osteosarcoma Cells
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Article
Induction of G1/S phase arrest and apoptosis by quercetin in human osteosarcoma cells
Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is a polyphenolic flavonoid compound and is found in a variety of plants. Potential biological activities including antioxidant and anticarcinogenesis have been repo...
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Article
Notch keeps ependymal cells in line
The ependymal cells lining the lateral ventricles are not stem cells, but a study now shows that they can be activated to generate neuroblasts in a stroke model, and mature olfactory bulb neurons when Notch si...
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Chapter
Role of PITX2 in the Pituitary Gland
The pituitary gland is a neuroendocrine organ composed of specialized peptide hormone-producing cells that control many bodily functions. Pituitary development depends on the combined activity of extrinsic sig...
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Chapter
Application of Tissue Engineering to Cartilage Repair
Once damaged, articular cartilage very rarely undergoes spontaneous healing, primarily because of the avascular nature of the tissue (Hunter 1743; Campbell 1969; Mankin 1982). Although many repair techniques h...
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Chapter
Potential Applications of Gene Therapy to the Treatment of Spinal Disorders
Spinal disorders remain a formidable problem in orthopaedics and sports medicine. The scope of clinical diagnoses ranges from acute traumatic injuries (e.g., fractures and subluxations) to more chronic degener...
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Article
The bicoid-related Pitx gene family in development
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Article
Mechanical stimulation of cartilage, ligment and tendon
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Chapter and Conference Paper
A Finite Element Formulation for Soft Hydrated Tissues
The function of the normal articulating joint or soft tissue component of the human body is a complex three dimensional problem often involving materials which undergo significant nonlinear behavior and multi-...
