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  1. Article

    Open Access

    Improve the efficiency and accuracy of ophthalmologists’ clinical decision-making based on AI technology

    As global aging intensifies, the prevalence of ocular fundus diseases continues to rise. In China, the tense doctor-patient ratio poses numerous challenges for the early diagnosis and treatment of ocular fundu...

    Yingxuan Guo, Changke Huang, Yaying Sheng in BMC Medical Informatics and Decision Making (2024)

  2. Article

    Open Access

    Application of 3D bioprinting technology apply to assessing Dangguiniantongtang (DGNT) decoctions in arthritis

    The aim of this study was to develop a three-dimensional (3D) cell model in order to evaluate the effectiveness of a traditional Chinese medicine decoction in the treatment of arthritis. Chondrocytes (ATDC5) a...

    Zhichao Liang, Yunxi Han, Tao Chen, **wu Wang, Kaili Lin, Luying Yuan in Chinese Medicine (2024)

  3. Article

    Open Access

    Deciphering glutamine metabolism patterns for malignancy and tumor microenvironment in clear cell renal cell carcinoma

    Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer characterized by metabolic reprogramming. Glutamine metabolism is pivotal in metabolic reprogramming, contributing to the sig...

    Gengrun Wu, Teng Li, Yuanbiao Chen, Shiqi Ye in Clinical and Experimental Medicine (2024)

  4. No Access

    Article

    Temporal relationship between hepatic steatosis and blood pressure elevation and the mediation effect in the development of cardiovascular disease

    The temporal relationship between non-alcoholic fatty liver disease (NAFLD) and hypertension remains highly controversial, with ongoing debates on whether NAFLD induces hypertension or vice versa. We employed ...

    Yifan Hu, Wenge Tang, Yujie Liu, Ning Zhang, **ngren Zhu, Dan Tang in Hypertension Research (2024)

  5. No Access

    Article

    Ventriculoperitoneal shunting obstruction: a multicentre clinical audit for cerebrospinal fluid parameters and its prediction role

    Shunt obstruction is a type of ventriculoperitoneal shunt (VPS) failure. Whether changes in cerebrospinal fluid (CSF) parameters can influence shunt outcomes or not is debatable.

    Hao Xu, Jiawei He, Shouren Chen, Caiquan Huang, Kai Zhao in Neurological Sciences (2024)

  6. Article

    Open Access

    Association of total sleep duration variability with risk of new stroke in the middle-aged and elderly Chinese population

    To investigate the association between total sleep duration variability and stroke in the middle-aged and elderly population in China.

    Jiang** Ma, Nuo Ma, Lu Zhang, Linghao Xu, Xueyuan Liu, Guilin Meng in BMC Neurology (2024)

  7. Article

    Open Access

    Causal associations between gut microbiota and chronic prostatitis/chronic pelvic pain syndrome: a two-sample Mendelian randomization study

    Recent researches have increasingly indicated a strong correlation between the gut microbiota and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Nevertheless, the impact of gut microbiota on CP/CP...

    Hao Xu, Yu Zhang, Yinglang Zhang, Chong Shen in Egyptian Journal of Medical Human Genetics (2024)

  8. Article

    Open Access

    Prognostic biomarker tumor-infiltrating lymphocytes failed to serve as a predictive biomarker for postoperative radiotherapy in completely resected pN2 non-small cell lung cancer: a retrospective analysis

    Evidence suggests that radiotherapy is a potent immunomodulator in non-small cell lung cancer (NSCLC). Conversely, it has rarely been demonstrated if immune infiltration can influence radiotherapy efficacy. He...

    Jiaran Li, Li Li, **g**g Wang, Ning Liu, Haixin Liu, Fuhao Xu in Respiratory Research (2024)

  9. Article

    Open Access

    Identification of novel risk factors for postoperative severe hypocalcemia in patients with primary hyperparathyroidism undergoing parathyroidectomy: a case control study

    Patients with primary hyperparathyroidism (PHPT) are at risk for severe hypocalcemia (SH) following parathyroidectomy (PTX), but limited data exist on the predictors of SH. We aimed to identify risk factors fo...

    Jiahao Xu, Na Kong, Nan Bai, Ziqin Zhang, Aimin Cui, Shen Tan in BMC Endocrine Disorders (2024)

  10. Article

    Open Access

    Correction: Anti-lymphangiogenesis for boosting drug accumulation in tumors

    Chunling Wang, Junchao Xu, **aoyu Cheng, Ge Sun in Signal Transduction and Targeted Therapy (2024)

  11. Article

    Open Access

    Changes in the combination of the triglyceride-glucose index and obesity indicators estimate the risk of cardiovascular disease

    Cardiovascular disease (CVD) is closely associated with the triglyceride glucose (TyG) index and its related indicators, particularly its combination with obesity indices. However, there is limited research on...

    **aoqing Zhu, Weihao Xu, Tingting Song, **nyan Wang in Cardiovascular Diabetology (2024)

  12. Article

    Open Access

    Trends in prevalence of arthritis by race among adults in the United States, 2011–2018

    There is currently a lack of comprehensive prevalence information on arthritis and its various classifications among adults in the U.S., particularly given the notable absence of detailed data regarding the As...

    Shenghao Xu, **anyue Shen, Bo Chen, Yingqiao Sun, **ongfeng Tang in BMC Public Health (2024)

  13. No Access

    Article

    Haplotype analysis on association between C-reactive protein gene and susceptibility to type 2 diabetes mellitus in Chinese Han population

    We aimed to evaluate the impact of C-reactive protein (CRP) gene polymorphism, additional gene–gene interaction, and haplotypes on susceptibility to type 2 diabetes mellitus (T2DM).

    Wen-Shu Luo, De-Ren Qiang, Wen-Rong Zhu, **ao-Ling Kong, Wen-Chao Xu in Acta Diabetologica (2024)

  14. Article

    Correction to: Semi-automatic proximal humeral trabecular bone density assessment tool: technique application and clinical validation

    De-Ming Guo, Yuan-Zhi Weng, Ze-Hao Yu, Shi-Huai Li in Osteoporosis International (2024)

  15. No Access

    Article

    Semi-automatic proximal humeral trabecular bone density assessment tool: technique application and clinical validation

    This study aimed to apply a newly developed semi-automatic phantom-less QCT (PL-QCT) to measure proximal humerus trabecular bone density based on chest CT and verify its accuracy and precision.

    De-Ming Guo, Yuan-Zhi Weng, Ze-Hao Yu, Shi-Huai Li in Osteoporosis International (2024)

  16. No Access

    Article

    Development and Validation of a Prognostic Model for Postoperative Anastomotic Recurrence in Siewert II or III Adenocarcinomas Without Neoadjuvant Therapy in an East Asian Population

    Anastomotic recurrence leads to poor prognosis in patients with Siewert II or III adenocarcinoma who undergo radical gastrectomy and do not receive neoadjuvant therapy. We aimed to establish a prognostic model...

    Ming-bin Huang, Chao Xu, Hong Chen, Jian-xian Lin in Journal of Gastrointestinal Cancer (2024)

  17. No Access

    Article

    Mediation effect of antithrombin III between chronic renal insufficiency and chronic coronary artery disease in T2DM patients

    The study aimed to investigate the potential effect of Antithrombin III (ATIII) between chronic renal insufficiency and chronic coronary artery disease (chronic CAD) in type 2 diabetes mellitus (T2DM) patients.

    Ruoyu Sun, Jianhong Jia, Shaohua Wang, Zheng Wang, Chenchen Wang, Yanchao Xu in Endocrine (2024)

  18. No Access

    Article

    Association between elevated preoperative red cell distribution width and mortality after brain tumor craniotomy

    Background: Red cell distribution width (RDW) has been recognized as a potential inflammatory biomarker, with elevated levels associated with adverse outcomes in various diseases. However, its role in predicti...

    Peng Wang, Yu Zhang, Wenhao Xu, Yuxin Zheng, Lu Jia, Jialing He in Neurosurgical Review (2024)

  19. Article

    Open Access

    An-Gong-Niu-Huang-Wan (AGNHW) regulates cerebral blood flow by improving hypoperfusion, cerebrovascular reactivity and microcirculation disturbances after stroke

    The restoration of cerebrovascular regulation and improvement of cerebral blood flow in ischaemic regions are crucial for improving the clinical prognosis after stroke. An-Gong-Niu-Huang-Wan (AGNHW) is a famou...

    **ao Zhang, Jiamin Pei, Lu** Xue, Zhe Zhao, Renhao Xu, Cong Zhang in Chinese Medicine (2024)

  20. Article

    Open Access

    Association Between Vitamin D Level and Clinical Outcomes of Assisted Reproductive Treatment: A Systematic Review and Dose-Response Meta-Analysis

    The investigation about association between vitamin D level and clinical outcomes of assisted reproductive treatment showed various outcomes. This study aimed to review the correlation between vitamin D and ou...

    Chenhao Xu, **nqi An, **umei Tang, Yunxiao Yang, Qi Deng in Reproductive Sciences (2024)

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