18 Result(s)
within
**gyou Yu
Life Sciences
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Article
Open AccessBiofilm-producing ability of methicillin-resistant Staphylococcus aureus clinically isolated in China
Staphylococcus aureus, a commensal bacterium, colonizes the skin and mucous membranes of approximately 30% of the human population. Apart from conventional resistance mechanisms, one of the pathogenic features of...
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Article
Open AccessYoung SINEs in pig genomes impact gene regulation, genetic diversity, and complex traits
Transposable elements (TEs) are a major source of genetic polymorphisms and play a role in chromatin architecture, gene regulatory networks, and genomic evolution. However, their functional role in pigs and co...
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Open AccessCirculating expression and clinical significance of LncRNA ANRIL in diabetic kidney disease
Long noncoding RNA ANRIL has been found to be involved in the pathogenesis of diabetic kidney disease (DKD) and is expected to be a new target for prevention of DKD. However, the circulating expression and cli...
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Open AccessDietary supplementation of Macleaya cordata extract and Bacillus in combination improve laying performance by regulating reproductive hormones, intestinal microbiota and barrier function of laying hens
This study aimed to investigate whether the combination of Macleaya cordata extract (MCE) and Bacillus could improve the laying performance and health of laying hens better.
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Open AccessmRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant
The SARS-CoV-2 Omicron variant evades vaccine-induced immunity. While a booster dose of ancestral mRNA vaccines effectively elicits neutralizing antibodies against variants, its efficacy against Omicron in old...
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Effects of High-Dose of Copper Amino Acid Complex on Laying Performance, Hematological and Biochemical Parameters, Organ Index, and Histopathology in Laying Hens
The objective of the study was to evaluate the maximum tolerance limit of amino acid copper complex (Cu-Lys-Glu) for laying hens by measuring their laying performance, hematological and serum biochemical param...
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Open AccessDistribution of fluoroquinolone resistance determinants in Carbapenem-resistant Klebsiella pneumoniae clinical isolates associated with bloodstream infections in China
The rate of fluoroquinolone (FQ) resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) is high. The present study aimed to investigate the distribution of fluoroquinolone resistance determinants in c...
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Open AccessThe small molecule ZY-214-4 may reduce the virulence of Staphylococcus aureus by inhibiting pigment production
In recent years, clinical Staphylococcus aureus isolates have become highly resistant to antibiotics, which has raised concerns about the ability to control infections by these organisms. The aim of this study wa...
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Open AccessResveratrol enhances the antimicrobial effect of polymyxin B on Klebsiella pneumoniae and Escherichia coli isolates with polymyxin B resistance
Multidrug resistant (MDR) Gram-negative bacterial infections are a serious threat to human health due to the lack of effective treatments. In this study, we selected 50 Gram-negative bacterial strains, includi...
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Open AccessOptimal dietary copper requirements and relative bioavailability for weanling pigs fed either copper proteinate or tribasic copper chloride
The objective of this study was to determine the effects of supplementing Cu on growth performance, Cu metabolism and Cu-related enzyme activities of weanling pigs fed diets with two different Cu sources, and ...
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Open AccessAntimicrobial susceptibility, virulence determinants profiles and molecular characteristics of Staphylococcus epidermidis isolates in Wenzhou, eastern China
Staphylococcus epidermidis has emerged as an often encountered pathogen responsible for hospital-acquired infections. The aim of present study is to investigate the microbiological characteristic of S. epidermidi...
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Open AccessRegulation of the small GTPase Rab1 function by a bacterial glucosyltransferase
Posttranslational modification of key host proteins by virulence factors is an important theme in bacterial pathogenesis. A remarkable example is the reversible modifications of the small GTPase Rab1 by multip...
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Open AccessCharacteristic of Enterococcus faecium clinical isolates with quinupristin/dalfopristin resistance in China
Quinupristin/dalfopristin (Q/D) is a valuable alternative antibiotic to vancomycin for the treatment of multi-drug resistant Enterococcus faecium infections. However, resistance to Q/D in E. faecium clinical isol...
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Effects of Replacing of Inorganic Trace Minerals by Organically Bound Trace Minerals on Growth Performance, Tissue Mineral Status, and Fecal Mineral Excretion in Commercial Grower-Finisher Pigs
A total of 180 crossbred pigs (Duroc × Landrace × Large White; BW = 47.1 ± 4.8 kg) were used to investigate the effects of totally replacing inorganic trace minerals (ITMs) by organically bound trace minerals ...
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Open AccessDissemination of fusidic acid resistance among Staphylococcus aureus clinical isolates
A significant trend towards increased fusidic acid (FA) resistance among Staphylococcus aureus with increased duration of use is of concern. The aim of the present study is to investigate the dissemination of fus...
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Open AccessFirst identification of coexistence of blaNDM-1 and blaCMY-42among Escherichia coli ST167 clinical isolates
Emergence of multidrug resistance in Enterobacteriaceae limits the selection of antimicrobials for treatment of infectious diseases. Identification of NDM-1 makes more difficulty in treating multidrug-resistant E...
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Open AccessRole of the SaeRS two-component regulatory system in Staphylococcus epidermidisautolysis and biofilm formation
Staphylococcus epidermidis (SE) has emerged as one of the most important causes of nosocomial infections. The SaeRS two-component signal transduction system (TCS) influences virulence and biofilm formation in Sta...
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Open AccessImpact of the Staphylococcus epidermidis LytSR two-component regulatory system on murein hydrolase activity, pyruvate utilization and global transcriptional profile
Staphylococcus epidermidis has emerged as one of the most important nosocomial pathogens, mainly because of its ability to colonize implanted biomaterials by forming a biofilm. Extensive studies are focused on th...
