15 Result(s)
within
**gying Huang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessEffect of different shapes of steel fibers and palygorskite-nanofibers on performance of ultra-high-performance concrete
Herein, a practical ultra-high-performance concrete (UHPC) was created by adding two different shapes of steel fibers and curing them at ambient temperature using palygorskite-nanofiber (PN) as the modifier. T...
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Open AccessMED19 encodes two unique protein isoforms that confer prostate cancer growth under low androgen through distinct gene expression programs
MED19, a component of the mediator complex and a co-regulator of the androgen receptor (AR), is pivotal in prostate cancer cell proliferation. MED19 has two isoforms: a full-length “canonical” and a shorter “a...
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Open AccessTAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition
The histone acetyltransferase p300/CBP is composed of several conserved domains, among which, the TAZ2 domain is known as a protein-protein interaction domain that binds to E1A and various transcription factor...
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Open AccessA diagnostic model of autoimmune hepatitis in unknown liver injury based on noninvasive clinical data
All the diagnostic criteria of autoimmune hepatitis (AIH) include histopathology. However, some patients may delay getting this examination due to concerns about the risks of liver biopsy. Therefore, we aimed ...
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Open AccessWhole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets
Alpha-fetoprotein producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of gastric cancer. However, little is known about the genomic features of this disease. We perform whole-exome sequencing ...
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Open AccessGlycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides
Both of O-glycosides and nucleosides are important biomolecules with crucial rules in numerous biological processes. Chemical synthesis is an efficient and scalable method to produce well-defined and pure carbohy...
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Open AccessRoom temperature electrofreezing of water yields a missing dense ice phase in the phase diagram
Water can freeze into diverse ice polymorphs depending on the external conditions such as temperature (T) and pressure (P). Herein, molecular dynamics simulations show evidence of a high-density orthorhombic phas...
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Open AccessRadiopaque Fully Degradable Nanocomposites for Coronary Stents
Bioresorbable scaffolds (BRS) were introduced to overcome limitations of current metallic drug-eluting stents and poly-L-lactide (PLLA) has been used in the fabrication of BRS due to its biodegradability and b...
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Open AccessBufalin suppresses hepatocarcinogenesis by targeting β-catenin/TCF signaling via cell cycle-related kinase
Hepatocellular carcinoma (HCC) is one of the most aggressive malignant tumors, of which treatment options are limited especially in advanced stage. Bufalin, the major digoxin-like component of the traditional ...
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Open AccessFusions of Tumor-derived Endothelial Cells with Dendritic Cells Induces Antitumor Immunity
To explore dendritic cells/tumor-derived endothelial cells (DC/EC) fusion cells are potent stimulators of T cells to impact tumor progression. ECs were isolated from mice hepatoma cell line (H22) Xenograft, an...
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Open AccessMeta-analysis of optical low-coherence reflectometry versus partial coherence interferometry biometry
A meta-analysis to compare ocular biometry measured by optical low-coherence reflectometry (Lenstar LS900; Haag Streit) and partial coherence interferometry (the IOLMaster optical biometer; Carl Zeiss Meditec)...
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Open AccesscAMP-PKA-CaMKII signaling pathway is involved in aggravated cardiotoxicity during Fuzi and Beimu Combination Treatment of Experimental Pulmonary Hypertension
Aconiti Lateralis Radix Praeparata (Fuzi) and Fritillariae Thunbergii bulbus (Beimu) have been widely used clinically to treat cardiopulmonary related diseases in China. However, according to the classic rules of...
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Article
Open AccessCXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylation
T-cell development in the thymus is largely controlled by an epigenetic program, involving in both DNA methylation and histone modifications. Previous studies have identified Cxxc1 as a regulator of both cytos...
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Article
Open AccessHigh expression of microRNA-183/182/96 cluster as a prognostic biomarker for breast cancer
More sensitive and effective diagnostic markers for the detection of breast cancer are urgently needed. The microRNA-183/182/96 cluster has been reported to be involved in tumorigenesis and progression in a va...
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Open AccessCoral reef ecosystems in the South China Sea as a source of atmospheric CO2 in summer
Field measurements of air-sea CO2 exchange in three coral reef areas of the South China Sea (i.e. the Yongshu Reef atoll of the Nansha Islands, southern South China Sea (SCS); Yongxing Island of **sha Islands, no...
