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Article
Open AccessHLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in mice
T cell receptor (TCR)-engineered T cell therapy is a promising potential treatment for solid tumors, with preliminary efficacy demonstrated in clinical trials. However, obtaining clinically effective TCR molec...
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Article
Open AccessSoft three-dimensional network materials with rational bio-mimetic designs
Many biological tissues offer J-shaped stress–strain responses, since their microstructures exhibit a three-dimensional (3D) network construction of curvy filamentary structures that lead to a bending-to-stret...
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Article
Open AccessSimulating the hydrologic cycle in coal mining subsidence areas with a distributed hydrologic model
Large-scale ground subsidence caused by coal mining and subsequent water-filling leads to serious environmental problems and economic losses, especially in plains with a high phreatic water level. Clarifying t...