-
Article
Myocardial perfusion improvement and mechanism after percutaneous intramyocardial septal radiofrequency ablation in obstructive hypertrophic cardiomyopathy: a study of myocardial contrast echocardiography
The data on myocardial perfusion of the percutaneous intramyocardial septal radiofrequency ablation (PIMSRA) for obstructive hypertrophic cardiomyopathy (HOCM) are still lacking, although PIMSRA have been prov...
-
Article
Relationship between perceived social support and postgraduate students’ general self-efficacy: a mediated model with moderation
Perceived social support is an essential factor influencing the mental health of individuals. To investigate the mechanisms of social support and general self-efficacy, this study investigated 485 graduate stu...
-
Article
CRL2APPBP2-mediated TSPYL2 degradation counteracts human mesenchymal stem cell senescence
Cullin-RING E3 ubiquitin ligases (CRLs), the largest family of multi-subunit E3 ubiquitin ligases in eukaryotic cells, represent core cellular machinery for executing protein degradation and maintaining proteo...
-
Article
Underwater acoustic target recognition based on knowledge distillation under working conditions mismatching
In marine economics and military activities, the timely recognition of underwater acoustic targets in complex environments is particularly important. The conditions of ship navigation can greatly affect the ra...
-
Article
Open AccessEstimating hourly surface shortwave radiation over northeast of the Tibetan Plateau by assimilating Himawari-8 cloud optical thickness
To reduce the uncertainty estimation of clouds and improve the forecast of surface shortwave radiation (SSR) over the Tibetan Plateau, a new cloud assimilation system is proposed which is the first attempt to ...
-
Article
CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord
Ageing is a critical factor in spinal-cord-associated disorders1, yet the ageing-specific mechanisms underlying this relationship remain poorly understood. Here, to address this knowledge gap, we combined single-...
-
Article
SIRT2 counteracts primate cardiac aging via deacetylation of STAT3 that silences CDKN2B
Aging is a major risk factor contributing to pathophysiological changes in the heart, yet its intrinsic mechanisms have been largely unexplored in primates. In this study, we investigated the hypertrophic and ...
-
Article
Open AccessSnow depth and snow cover over the Tibetan Plateau observed from space in against ERA5: matters of scale
There has been a statement that the satellite and reanalyses significantly overestimate snow depths (SDs) as compared with in-situ observations over the Tibetan Plateau (TP). The inconsistency may be partly du...
-
Article
Dynamics of the gold–silicon eutectic reaction studied at limited length scales using in situ TEM and STEM
The dynamics of the gold–silicon eutectic reaction in limited dimensions were studied using in situ transmission electron microscopy and scanning transmission electron microscopy heating experiments. The phase...
-
Article
Open AccessExosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis
-
Article
Open AccessCross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor
Regenerative capacity declines throughout evolution and with age. In this study, we asked whether metabolic programs underlying regenerative capability might be conserved across species, and if so, whether suc...
-
Article
Open AccessPatterns of yeast diversity distribution and its drivers in rhizosphere soil of Hami melon orchards in different regions of **njiang
The unique climatic conditions of the **njiang region nurture rich melon and fruit resources, the melon and fruit sugar sources provide sufficient nutrients for the survival of yeast, and the diverse habitats ...
-
Article
Open AccessFOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction
-
Article
Open AccessPredictors of cardiac involvement and survival in patients with primary systemic light-chain amyloidosis: roles of the clinical, chemical, and 3-D speckle tracking echocardiography parameters
Light-chain (AL) amyloidosis is the most common type of systemic amyloidosis with poor prognosis. Currently, the predictors of cardiac involvement and prognostic staging systems are primarily based on conventi...
-
Article
Open AccessReactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer
Anlotinib (AL3818), a novel multi-targeted receptor tyrosine kinase inhibitor, has recently been proven to be an antitumour drug. This study aimed to explore the antitumour effect of anlotinib and its underlyi...
-
Article
Reply to: How much does corrosion of nuclear waste matrices matter
-
Article
A site-selective amination catalyst discriminates between nearly identical C–H bonds of unsymmetrical disubstituted alkenes
C–H activation reactions enable chemists to unveil new retrosynthetic disconnections and streamline conventional synthetic approaches. A long-standing challenge in C–H activation is the inability to distinguis...
-
Article
Open AccessCorrosion interactions between stainless steel and lead vanado-iodoapatite nuclear waste form part II
This paper studied the release of iodine from lead vanado-iodoapatite (I-APT, Pb9.85(VO4)6I1.7), a potential nuclear waste form for the radioactive waste element of I-129, which can be enhanced when crevice corro...
-
Article
A review of the estimation of downward surface shortwave radiation based on satellite data: Methods, progress and problems
The estimation of downward surface shortwave radiation (DSSR) is important for the Earth’s energy budget and climate change studies. This review was organised from the perspectives of satellite sensors, algori...
-
Article
Open AccessA single-cell transcriptomic landscape of primate arterial aging
Our understanding of how aging affects the cellular and molecular components of the vasculature and contributes to cardiovascular diseases is still limited. Here we report a single-cell transcriptomic survey o...
