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  1. No Access

    Article

    Putative role of uncoupling proteins in mitochondria-nucleus communications and DNA damage response

    Mitochondria-nucleus communications and DNA damage response (DDR) play roles in cellular stress and closely associate with a range of diseases. Mitochondrial uncoupling proteins (UCPs) are capable of uncouplin...

    Yahan Niu, Chang Liu, Rui Zhang, Ying **g, Donghai Li in Journal of Biosciences (2021)

  2. Article

    Open Access

    Allogeneic vs. autologous mesenchymal stem/stromal cells in their medication practice

    Mesenchymal stem/stromal cell (MSC)-based therapeutics is already available for treatment of a range of diseases or medical conditions. Autologous or allogeneic MSCs obtained from self or donors have their own...

    Chenghai Li, Hua Zhao, Linna Cheng, Bin Wang in Cell & Bioscience (2021)

  3. No Access

    Article

    Introduction of heterologous transcription factors and their target genes into Penicillium oxalicum leads to increased lignocellulolytic enzyme production

    Genetic engineering of transcription factors is an efficient strategy to improve lignocellulolytic enzyme production in fungi. In this study, the xylanase transcriptional regulators of Trichoderma reesei (Xyr1) a...

    Chengqiang **a, Zhonghai Li, Yanning Xu in Applied Microbiology and Biotechnology (2019)

  4. Article

    Open Access

    Cow manure as a lignocellulosic substrate for fungal cellulase expression and bioethanol production

    Conversion of various lignocellulosic materials into bioethanol is growing in demand but greatly depends on feedstock availability. Dairy cow manure is an agricultural waste widely distributed worldwide. This ...

    Qin Yan, **nli Liu, Yanan Wang, Hongxing Li, Zhigang Li, Lin Zhou, Yinbo Qu in AMB Express (2018)

  5. No Access

    Article

    Large-scale cultivation of Spirulina in a floating horizontal photobioreactor without aeration or an agitation device

    A low-cost floating photobioreactor (PBR) without the use of aeration and/or an agitation device, in which carbon was supplied in the form of bicarbonate and only wave energy was utilized for mixing, was devel...

    Chenba Zhu, **aoqian Zhai, **ghan Wang in Applied Microbiology and Biotechnology (2018)

  6. No Access

    Article

    Cellodextrin transporters play important roles in cellulase induction in the cellulolytic fungus Penicillium oxalicum

    Cellodextrin transporters (cellodextrin permeases) have been identified in fungi in recent years. However, the functions of these transporters in cellulose utilization and cellulase expression have not been we...

    Jie Li, Guodong Liu, Mei Chen, Zhonghai Li in Applied Microbiology and Biotechnology (2013)

  7. No Access

    Article

    Construction of engineered Arthrobacter simplex with improved performance for cortisone acetate biotransformation

    Arthrobacter simplex 156 is a microorganism that is used for steroid drug biotransformation of cortisone acetate (CA) to prednisone acetate (PA). The enzyme 3-ketosteroid-△1-dehydrogenase encoded...

    Huitu Zhang, Yao Tian, Jianling Wang, Yonghai Li in Applied Microbiology and Biotechnology (2013)

  8. No Access

    Article

    Microbial diversity in the snow, a moraine lake and a stream in Himalayan glacier

    The microbial diversity and abundance in surface snow at different altitudes (5300 and 5504 m above sea level), a moraine lake and a glacial stream in the Yala Glacier on the southern slope of the Himalayas we...

    Yongqin Liu, Tandong Yao, Nianzhi Jiao, Lide Tian, Anyi Hu, Wusheng Yu in Extremophiles (2011)

  9. Article

    7-O-descarbamoyl-7-hydroxygeldanamycin, a minor component from the gdmN disruption mutant of Streptomyces hygroscopicus 17997

    Siyang Ni, Linzhuan Wu, Hongyuan Wang, Yiguang Wang in The Journal of Antibiotics (2010)

  10. Article

    A New Post-PKS Modification Process in the Carbamoyltransferase Gene Inactivation Strain of Streptomyces hygroscopicus 17997

    Genetic manipulation of geldanamycin (GDM) producer Streptomyces species is a rational approach to understand biosynthesis processes and create new analogues. In this study, the carbamoyltransferase gene gdmN was...

    Yonghai Li, Weiqing He, Yucheng Wang, Yiguang Wang in The Journal of Antibiotics (2008)