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Article
Open AccessCombining manipulation of transcription factors and overexpression of the target genes to enhance lignocellulolytic enzyme production in Penicillium oxalicum
Lignocellulolytic enzymes are the main enzymes to saccharify lignocellulose from renewable plant biomass in the bio-based economy. The production of these enzymes is transcriptionally regulated by multiple tra...
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Article
Open AccessProduction of a high-efficiency cellulase complex via β-glucosidase engineering in Penicillium oxalicum
Trichoderma reesei is a widely used model cellulolytic fungus, supplying a highly effective cellulase production system. Recently, the biofuel industry discovered filamentous fungi fro...
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Article
Open AccessRedesigning the regulatory pathway to enhance cellulase production in Penicillium oxalicum
In cellulolytic fungi, induction and repression mechanisms synchronously regulate the synthesis of cellulolytic enzymes for accurate responses to carbon sources in the environment. Many proteins, particularly ...