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626 Result(s)
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Article
Synchronization and complex dynamics in locally active threshold memristive neurons with chemical synapses
Memristor has been extensively employed to emulate neuron/synapse-inspired behaviors and to characterize the electromagnetic induction generated by ionic flowing. A link between memristive features and neural ...
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Open AccessInhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice
Kidney fibrosis is considered to be the ultimate aggregation pathway of chronic kidney disease (CKD), but its underlying mechanism remains elusive. Protein kinase C-delta (PKC-δ) plays critical roles in the co...
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Article
Too great to be more prosocial: the relationship between collective narcissism and humanitarian aid in the Chinese context
Collective narcissism, as a belief about the in-group’s exceptionality, is broadly studied in general inter-group relationships. While collective narcissism is gaining more and more attention, little research ...
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Open AccessDeep learning image reconstruction generates thinner slice iodine maps with improved image quality to increase diagnostic acceptance and lesion conspicuity: a prospective study on abdominal dual-energy CT
To assess the improvement of image quality and diagnostic acceptance of thinner slice iodine maps enabled by deep learning image reconstruction (DLIR) in abdominal dual-energy CT (DECT).
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Open AccessFunctional genetic variants of GEN1 predict overall survival of Chinese epithelial ovarian cancer patients
Inherited variations in DNA double-strand break (DSB) repair pathway are known to influence ovarian cancer occurrence, progression and treatment response. Despite its significance, survival-associated genetic ...
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Open AccessRetraction Note: LncRNA PCAT6 regulates the progression of pituitary adenomas by regulating the miR-139-3p/BRD4 axis
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Linkage of intellectual humility and identification with all humanity among Chinese adolescents: the role of openness to diversity and intergroup contact
The peaceful and stable development of the world has always been an essential issue of common concern for humanity. In recent years, abundant studies have found that identification with all humanity (IWAH) is ...
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Article
Competitive sorption of arsenic and antimony onto synthetic ferrous sulfide
The competitive sorption of arsenite, As(III), and antimonite, Sb(III) on mackinawite (FeS) was investigated, so as to better understand the influence between As(III) and Sb(III) in anaerobic water, soil, or s...
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Article
Enzymatic C1 reduction using hydrogen in cofactor regeneration
Carbon dioxide fixation presents a potential solution for mitigating the greenhouse gas issue. During carbon dioxide fixation, C1 compound reduction requires a high energy supply. Thermodynamic calculations su...
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Open AccessNatural evidence of coronaviral 2′-O-methyltransferase activity affecting viral pathogenesis via improved substrate RNA binding
Previous studies through targeted mutagenesis of K-D-K-E motif have demonstrated that 2′-O-MTase activity is essential for efficient viral replication and immune evasion. However, the K-D-K-E catalytic motif o...
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Open AccessThe relationship between oxidative balance scores and chronic diarrhea and constipation: a population-based study
Oxidative stress is closely related to gut health. Exposures to oxidative stress in one’s diet and lifestyle can be evaluated by the oxidative balance score (OBS). However, the relationship between OBS and int...
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Article
Predictive modeling of diverse factors impacting regional soil erosion degree with machine learning
Soil erosion is an obstacle in the process of maintaining and restoring the ecological environment in desert steppe landforms. We studied soil erosion in typical desert steppe landform areas in the northern fo...
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Article
Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1
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Open AccessUnraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states
This study aims to elucidate the transcriptomic signatures and dysregulated pathways in patients with Systemic Lupus Erythematosus (SLE), with a particular focus on those persisting during disease remission.
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Prespecified-time control of switched neural networks: novel Lyapunov approach of prespecified-time stability
This article is concerned with the prespecified-time stability problem for a type of non-linear system with discontinuity. Based on arctangent function and exponential function, several novel prespecified-time...
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Article
Open AccessTumour-selective activity of RAS-GTP inhibition in pancreatic cancer
Broad-spectrum RAS inhibition has the potential to benefit roughly a quarter of human patients with cancer whose tumours are driven by RAS mutations1,2. RMC-7977 is a highly selective inhibitor of the active GTP-...
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Open AccessConcurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy
RAS oncogenes (collectively NRAS, HRAS and especially KRAS) are among the most frequently mutated genes in cancer, with common driver mutations occurring at codons 12, 13 and 611. Small molecule inhibitors of the...
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Article
Open AccessImprovement of roughness in ultrasonic assisted magnetorheological finishing of small titanium alloy nuts by orthogonal test method
Titanium alloy with high corrosion resistance, high strength-to-density ratio, and excellent biocompatibility has a wide range of applications in the field of biomedical implants. Polishing experiments of tita...
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Article
Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3
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Article
The Longitudinal Associations Between Parental Autonomy Support, Autonomy and Peer Resistance
Adolescents’ autonomy is considered to be shaped within family and peer contexts. However, the specific dynamics of the within-person associations between parental autonomy support, adolescents’ general autono...