68 Result(s)

Article

Global variability in atmospheric new particle formation mechanisms

A key challenge in aerosol pollution studies and climate change assessment is to understand how atmospheric aerosol particles are initially formed^1,2. Although new particle formation (NPF) mechanisms have been de...

Bin Zhao, Neil M. Donahue, Kai Zhang, Lizhuo Mao, Manish Shrivastava, Po-Lun Ma… in Nature (2024)

Article

HBV promotes its replication by up-regulating RAD51C gene expression

Chronic hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC), pegylated-interferon-α(PEG-IFNα) and long-term nucleos(t)ide analogs (NUCs) are mainly drugs used to treat HBV infe...

Ting-wei Peng, Qing-feng Ma, Jie Li, Xue Wang, Cong-hui Zhang… in Scientific Reports (2024)

Article

Temporally-coordinated bivalent histone modifications of BCG1 enable fungal invasion and immune evasion

Bivalent histone modifications, including functionally opposite H3K4me3 and H3K27me3 marks simultaneously on the same nucleosome, control various cellular processes by fine-tuning the gene expression in eukary...

**aozhen Zhao, Yiming Wang, Bingqin Yuan, Hanxi Zhao, Yujie Wang… in Nature Communications (2024)

Article

Proteomic characterization of epithelial ovarian cancer delineates molecular signatures and therapeutic targets in distinct histological subtypes

Clear cell carcinoma (CCC), endometrioid carcinoma (EC), and serous carcinoma (SC) are the major histological subtypes of epithelial ovarian cancer (EOC), whose differences in carcinogenesis are still unclear....

Ting-Ting Gong, Shuang Guo, Fang-Hua Liu, Yun-Long Huo, Meng Zhang… in Nature Communications (2023)

Article

Key role of e_g^* band broadening in nickel-based oxyhydroxides on coupled oxygen evolution mechanism

A coupled oxygen evolution mechanism (COM) during oxygen evolution reaction (OER) has been reported in nickel oxyhydroxides (NiOOH)-based materials by realizing e_g^* band (3d electron states with e_g symmetry) broa...

Haoyin Zhong, Qi Zhang, Junchen Yu, **n Zhang, Chao Wu, Hang An… in Nature Communications (2023)

Article

GDF11 slows excitatory neuronal senescence and brain ageing by repressing p21

As a major neuron type in the brain, the excitatory neuron (EN) regulates the lifespan in C. elegans. How the EN acquires senescence, however, is unknown. Here, we show that growth differentiation factor 11 (G...

Di-**an Wang, Zhao-Jun Dong, Sui-**n Deng, Ying-Ming Tian… in Nature Communications (2023)

Article

Retraction Note: Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression

Gui-fang Zhu, Yang-wei Xu, Jian Li, Hui-lin Niu, Wen-xia Ma… in Nature Communications (2023)

Article

R-loop-dependent promoter-proximal termination ensures genome stability

The proper regulation of transcription is essential for maintaining genome integrity and executing other downstream cellular functions^1,2. Here we identify a stable association between the genome-stability regula...

Congling Xu, Chengyu Li, Jiwei Chen, Yan **ong, Zhibin Qiao, Pengyu Fan… in Nature (2023)

Article

Regio- and enantioselective CuH-catalyzed 1,2- and 1,4-hydrosilylation of 1,3-enynes

We report a copper-catalyzed ligand-controlled selective 1,2- and 1,4-hydrosilylation of 1,3-enynes, which furnishes enantiomerically enriched propargyl- and 1,2-allenylsilane products in high yields with exce...

Zi-Lu Wang, Qi Li, Meng-Wei Yang, Zhao-**n Song, Zhen-Yu **ao… in Nature Communications (2023)

Article

Evaluation of product conceptual design based on Pythagorean fuzzy set under big data environment

The concept design evaluation phase of the new product launch is extremely important. However, current evaluation information relies mainly on the a priori knowledge of decision makers and is subjective and am...

Lian-Dan Ma, Wei-**ng Wang, **g-Wen **e, Ning Zhang, Ning-Feng Hu… in Scientific Reports (2022)

Article

Engineered helicase replaces thermocycler in DNA amplification while retaining desired PCR characteristics

Polymerase Chain Reaction (PCR) is an essential method in molecular diagnostics and life sciences. PCR requires thermal cycling for heating the DNA for strand separation and cooling it for replication. The pro...

Momčilo Gavrilov, Joshua Y. C. Yang, Roger S. Zou, Wen Ma… in Nature Communications (2022)

Article

Flavin-enabled reductive and oxidative epoxide ring opening reactions

Epoxide ring opening reactions are common and important in both biological processes and synthetic applications and can be catalyzed in a non-redox manner by epoxide hydrolases or reductively by oxidoreductase...

Bidhan Chandra De, Wenjun Zhang, Chunfang Yang, Attila Mándi… in Nature Communications (2022)

Article

Inhibition of myeloid-derived suppressor cell arginase-1 production enhances T-cell-based immunotherapy against Cryptococcus neoformans infection

Cryptococcosis is a potentially lethal disease that is primarily caused by the fungus Cryptococcus neoformans, treatment options for cryptococcosis are limited. Here, we show glucuronoxylomannan, the major polysa...

Ya-Nan Li, Zhong-Wei Wang, Fan Li, Ling-Hong Zhou, Yan-Shan Jiang… in Nature Communications (2022)

Article

Structural insights into dsRNA processing by Drosophila Dicer-2–Loqs-PD

Small interfering RNAs (siRNAs) are the key components for RNA interference (RNAi), a conserved RNA-silencing mechanism in many eukaryotes^1,2. In Drosophila, an RNase III enzyme Dicer-2 (Dcr-2), aided by its cofa...

Shichen Su, Jia Wang, Ting Deng, Xun Yuan, **qiu He, Nan Liu, **aomin Li… in Nature (2022)

Article

Anomalous thermo-osmotic conversion performance of ionic covalent-organic-framework membranes in response to charge variations

Increasing the charge density of ionic membranes is believed to be beneficial for generating high output osmotic energy. Herein, we systematically investigated how the membrane charge populations affect permse...

Weipeng **an, **uhui Zuo, Changjia Zhu, Qing Guo, Qing-Wei Meng… in Nature Communications (2022)

Article

Gut microbiota-bile acid crosstalk contributes to the rebound weight gain after calorie restriction in mice

Calorie restriction (CR) and fasting are common approaches to weight reduction, but the maintenance is difficult after resuming food consumption. Meanwhile, the gut microbiome associated with energy harvest al...

Mengci Li, Shouli Wang, Yitao Li, Mingliang Zhao, Junliang Kuang… in Nature Communications (2022)

Article

A Chinese tale of three regions: a century of China in thousands of films

Over the past 70 years, because of their different historical and social contexts, the film industries of China’s three regions, namely mainland China, Taiwan, and the Hong Kong Special Administrative Region (...

Zhuo Chen, Wen Ma, Wei Guo, Yunsong Chen in Humanities and Social Sciences Communications (2022)

Article

Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing

The age-dependent decline in remyelination potential of the central nervous system during ageing is associated with a declined differentiation capacity of oligodendrocyte progenitor cells (OPCs). The molecular...

**ao-Ru Ma, Xudong Zhu, Yujie **ao, Hui-Min Gu… in Nature Communications (2022)